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Imanuel Setiawan, Stefanus
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Health Professions Medicine & Pharmacology Public Health

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Pilihan Tatalaksana Penyakit Perlemakan Hati Non-Alkohol (Non-Alcoholic Fatty Liver Disease/ NAFLD) Imanuel Setiawan, Stefanus; Kurniawan, Juferdy
Cermin Dunia Kedokteran Vol 48, No 3 (2021): Obstetri dan Ginekologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (95.345 KB) | DOI: 10.55175/cdk.v48i3.1336

Abstract

Penyakit perlemakan hati non-alkohol (Non-alcoholic fatty liver disease/ NAFLD) merupakan kondisi adanya steatosis hepatik, inflamasi, dan kerusakan hepatosit (ballooning degeneration). NAFLD tidak hanya dianggap penyakit hati primer, tetapi juga merupakan bagian dari sindrom metabolik atau kondisi resistensi insulin dan penyakit terkait gaya hidup seperti diabetes, dislipidemia, dan hipertensi. Strategi tatalaksana NAFLD dimulai dari modifikasi gaya hidup, dapat dilanjutkan dengan terapi komponen sindrom metabolik, farmakoterapi, hingga penatalaksanaan sirosis.Non-alcoholic fatty liver disease refers to a steatosis in liver, associated with inflammation and destruction of hepatocyte (ballooning degeneration). NAFLD is considered as primary liver disease, but also as a component of metabolic syndrome related to insulin resistance and other life-style-related diseases i.e diabetes mellitus, dyslipidemia, and hypertension. Strategies in NAFLD management start with life-style modification, continued with pharmacological approaches targeting metabolic syndrome and complications related to cirrhosis.
Co-Authors Juferdy Kurniawan