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All Journal International Journal Of Science, Technology & Management (IJSTM) FORTE JOURNAL
Pangondian Harahap, Aswan
Universitas Haji Sumatera Utara
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Standarisasi Dan Perbandingan Uji Aktivitas Antioksidan Dari Ekstrak Etanol Dan Dekok Daun Senggani ( Melastoma malabathricum L.) Dengan Menggunakan metode DPPH: STANDARISASI DAN PERBANDINGAN EFEKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAN DEKOK DAUN SENGGANI (Melastoma malabathricum L.) DENGAN METODE DPPH Aswan Pangondian Harahap; Robiatun Rambe; Ratih Paramitha; Yulanda Yulanda
FORTE JOURNAL Vol 2 No 1 (2022): Vol. 2 No. 1 (2022) : Edisi Januari
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/fj.v2i1.191

Abstract

Senggani (Melastoma malabathricum L.) banyak mengandung senyawa kimia  seperti alkaloid, flavonid, tanin, saponin dan steroid . Penelitian ini bertujuan untuk mengetahui efektivitas  antioksidan ekstrak etanol dan dekok daun senggani (Melastoma malabathricum L.) serta perbandingan nilai IC50 dari ekstrak etanol dan dekok daun senggani (Melastoma malabathricum L.). Metode Ekstraksi pada penelitian ini adalah maserasi menggunakan pelarut etanol 70% . dan dekok pelarut air pada suhu 90o  selama 30 menit.  Pengujian aktivitas antioksidan menggunakan metode peredaman peradaman radikal bebas DPPH. Hasil ekstrak dari hasil ekstraksi daun senggani menggunakan pelarut etanol  70% sebanyak 110,2 gram dengan persen rendemen sebesar 22,04 %. Hasil Dekok daun senggani pada  pelarut air sebanyak 49,90 gram rendemen ekstrak sebesar 24,95%. Dari Hasil Pengukuran Efektivitas antioksidan dengan nilai  IC50 ekstrak daun senggani (Melastoma malabathricum L.) sebesar 19,206 ppm, dan dekok daun senggani (Melastoma malabathricum L.) sebesar 17,140 ppm. Kesimpulan bahwa efektivitas antioksidan Ekstrak dan Dekok daun senggani (Melastoma malabathricum L.) diperoleh melalui metode pengujian dengan DPPH pada nilai IC50 ekstrak etanol daun senggani sebesar 19,206 ppm dan dekok daun senggani sebesar17.140 ppm dimana efektivitas antioksidan termasuk dalam kategori sangat kuat  , kedua sempel mempunyai efektivitas antioksidan tergolong sangat kuat tetapi Nilai IC50 dekok daun senggani (Melastoma malabathricum L.) lebih baik dibanding kan ekstrak daun senggani Melastoma malabathricum L.).
Formulation And Evaluation Of Hand Sanitizer Gel From Clove Flower Extract (Eugenia aromatica L.) Robiatun Rambe Robiatun; Aswan Pangondian; Ratih Paramitha; Zulmai Rani; Evi Depiana Gultom
International Journal of Science, Technology & Management Vol. 3 No. 2 (2022): March 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i2.472

Abstract

Clove flower (Eugenia aromatica L.) is a plant from the Myrtaceae family, the compounds contained in clove flowers are flavonoids, tannins, alkaloids, and saponins that can function as antibacterial. In addition, clove flowers also function as analgesic, anti-inflammatory, antimicrobial, antiviral, antifungal, antiseptic, antispasmodic, antiemetic, stimulant, and local anesthetic. The purpose of this study was to determine does clove flower extract (Eugenia aromatica L.) could be used as a hand sanitizer gel preparation. Clove flower simplicia powder was extracted with ethanol 96% by maceration. The extract obtained was then screened for phytochemicals, then formulated in the form of a hand sanitizer gel, by adding clove flower extract to each formula with different concentrations. The clove flower extract concentrations used were 5%, 10%, and 15%. After the hand sanitizer gel preparation was formed, the clove flower extract was then tested for the stability of the gel preparation. The clove flower extract obtained was 116.4 grams of thick extract. The results of phytochemical screening of clove flower extract showed the presence of secondary metabolites, namely flavonoids, alkaloids, saponins and tannins. Based on the evaluation of the hand sanitizer gel preparation, clove extract showed that it was physically stable during storage. Based on the acceptability or liking test conducted on 20 respondents using a questionnaire sheet, the results showed that the respondents really liked the aroma of formula F3.
Co-Authors Anisa Safira Sitorus Athaillah Athaillah Evi Depiana Gultom Putra Chandra Ratih Paramitha Ratih Paramitha Robiatun Rambe Yulanda Yulanda Zulmai Rani