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Lisna Astuti
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Health Professions Medicine & Pharmacology

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RADIONUCLIDE SCANNING WITH I-123 IN GRAVES DISEASE Putu Diah Vedayanti; Lisna Astuti; Elisanti Dwi Martadiani
E-Jurnal Medika Udayana vol 3 no 1 (2014):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Graves’ disease is the most common form of thyrotoxicosis which caused byautoimmune that attacks the thyroid gland. This disease will lead such followingsyndromes: thyrotoxicosis, goiter, ophthalmopathy, dermopathy. The sensitive TSHassay is the single best screening test for hyperthyroidism, and in most outpatientclinical situations. But when there is a doubt to distinguish diffuse toxic goiter (Graves’disease) from autonomous toxic nodule (Plummer’s disease), radioinuclide scanning canbe performed. I-123 is one of the preferable radiosisotope because it can produce clearimage and short enough half-life, although the price is expensive. 
18F-FLOURODEOXYGLUCOSE (18FDG) POSITRON-EMISSION TOMOGRAPHY (PET) AS IMAGING MODALITIES ON THYROID CANCER MANAGEMENT I Putu Ary Wismayana; Elysanti Dwi Martadiani; Lisna Astuti
E-Jurnal Medika Udayana vol 2 no 7 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Thyroid cancer prevalence tend to increase, by 2008 there are 37.340 cases with mortality rate reached 1.590. Traditionally USG and scintigraphy are major imaging modality to diagnose or predict the prognosis of thyroid cancer. On special case, ultrasonography or scintigraphy cannot be use due to anatomical change after surgical procedure or low iodine uptake. Positron-Emission Tomography (PET) is noninvasive, three-dimensional, nuclear imaging technique. PET can evaluate both anatomical and functional. 18F-Flourodeoxyglucose PET can evaluate function and abnormality of thyroid which cannot be evaluated using another imaging modalities. PET can detect papillary and follicular thyroid cancer relaps with negative increasing thyroglobuline and radioiodine scanning negative, instead of detects medularry thyroid cancer earlier. Benefits of PET limited due to cost and technology.
AKURASI ULTRASONOGRAFI DALAM MENDIAGNOSIS KANKER PAYUDARA DI RSUP SANGLAH DENPASAR Ruthie Aviana; Lisna Astuti; I Gst Agung Gd Mahendra Wijaya
E-Jurnal Medika Udayana Vol 8 No 9 (2019): Vol 8 No 9 (2019): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

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Abstract

Kanker payudara merupakan jenis kanker yang paling mematikan bagi wanita usia 20-59 tahun di seluruh dunia menurut World Health Organization (WHO). Di Indonesia, prevalensipenderita kanker payudara pada tahun 2013 adalah sebesar 0,5%. Pemeriksaan penunjangawal yang dapat dilakukan untuk membantu mengakkan diagnosis adalah ultrasonografi(USG) karena USG merupakan alat imaging yang aman, simple, bersifat noninvasif, danbanyak tersedia di rumah sakit. Penelitian ini bertujuan untuk mengetahui nilai diagnostikUSG dibandingkan dengan biopsi patologi anatomi dalam mendiagnosis kanker payudara diRSUP Sanglah Denpasar pada April 2016 – Februari 2017. Metode penelitian yang digunakanadalah uji diagnostik untuk menganalisa nilai sensitivitas dan spesifisitas alat USG denganmenggunakan consecutive sampling. Dari 66 sampel yang diperiksa pada pemeriksaan USG,93,94% sampel merupakan kanker payudara dan 6,06% sampel bukan kanker payudara.Sementara, didapatkan 93,94% sampel kanker payudara dan 6,06% sampel bukan kankerpayudara melalui pemeriksaan biopsi patologi anatomi. Berdasarkan hasil penelitian,didapatkan nilai sensitifitas USG sebesar 96,77%, spesifisitas sebesar 50,00%, nilai prediksipositif sebesar 96,77%, nilai prediksi negatif sebesar 50%, dan nilai akurasi sebesar 93,93%. Kata kunci: uji diagnostik, ultrasonografi, kanker payudara
Co-Authors Elysanti Dwi Martadiani I Gusti Agung Gede Mahendra Wijaya I Putu Ary Wismayana Putu Diah Vedayanti Ruthie Aviana