Article Per Year (5 Year)
p-Index From 2019 - 2024
0.408
P-Index
This Author published in this journals
All Journal Jurnal Prima Medika Sains
Marfitania, Taranipa
Unknown Affiliation
Health Professions Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Formulation and evaluation of red ginger extract tablet (Zingiber officinale var. rubrum) as lozenges Paramitha, Ratih; Marfitania, Taranipa; Januarti, Ria; Hanief, Said; Tambunan, Pravil Mistryanto
Jurnal Prima Medika Sains Vol. 6 No. 1 (2024): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i1.5256

Abstract

Red ginger (Zingiber officinale var. rubrum) with a high content of phenols (e.g. gingerol, shogaol, etc.) has potential effects against throat inflammation such as cold, sore throat, tonsilitis, etc. This research aims to determine the formulation of lozenge tablets using red ginger extracts. Lozenges tablets are made from dry ginger extract using a wet granulation method prepared by various concentrations of pregelatinized cassava starch 1 % w/v (F0); 2 % w/v (F1) and 5 % w/v (F2) as a binder and HPMC 2 % w/v (F3) as a comparative binder. Red ginger extract was prepared by maceration method using 96% ethanol solvent which is then evaporated using a rotary evaporator to obtain a thick extract. Thick red ginger extract is formulated into lozenges with various formulations F0, F1, F2, and F3. Physical characteristics evaluation of lozenge tablets includes physical appearance, weight uniformity, hardness, and disintegration time. The physical appearance of the tablet is round in shape and bright yellow in color. Based on the evaluation of all the formulas made, F2 has good criteria as a red ginger extract lozenge which has a hardness of 6 kg and disintegration time of 5 minutes 4 seconds.
Antibacterial activity of palm leaf extract against Propionibacterium acnes and Staphylococcus aureus Harmileni, Harmileni; Hidayani, Tengku Rachmi; Chiuman, Linda; Marfitania, Taranipa
Jurnal Prima Medika Sains Vol. 6 No. 1 (2024): June
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v6i1.5258

Abstract

Acne vulgaris is the most common skin disorder in adults and young adults. The growth of acne is caused by many factors, including excess sebum secretion and changes in microbial flora, mainly the colonization of Propionibacterium acnes and Staphylococcus aureus. This study aimed to determine the anti-bacterial activity of palm leaf extract against Propionibacterium acnes and Staphylococcus aureus. The research procedure includes palm leaf extraction and anti-bacterial tests. Palm leaf extraction was carried out using ultrasonication, while the anti-bacterial test was carried out using disc diffusion. The palm leaf extract obtained was diluted to 10, 20, 30, 50, and 50%, and each variation of this concentration was tested for anti-bacterial activity. The results of the anti-bacterial test showed that all palm leaf extract samples from 10% to 50% concentration could inhibit the growth of P. acnes and S. aureus bacteria. The 50% extract of ultrasonicated palm leaves had the largest inhibition zone diameter of 13.8 mm for P. acnes bacteria and 10.1 for S. aureus bacteria. From the results of this study, palm leaf extract has the potential to be used as a product for the prevention or treatment of acne vulgaris.
Co-Authors Chiuman, Linda Hanief, Said Harmileni, Harmileni Januarti, Ria Paramitha, Ratih Tambunan, Pravil Mistryanto Tengku Rachmi Hidayani, Tengku Rachmi