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Adi Heru Husodo
Universitas Gadjah Mada
Health Professions

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Determinants Levels of Urinary 8-Hydroxydeoxyguanosine among Chromium Electroplating Workers Yuliani Setyaningsih; Indwiani Astuti; Adi Heru Husodo
International Journal of Public Health Science (IJPHS) Vol 5, No 4: December 2016
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.261 KB) | DOI: 10.11591/ijphs.v5i4.4845

Abstract

Electroplating workers were exposed by particulate and fog of chromium from electrolysis process during work. Chromium is highly carcinogenic when inhaled.  Chromium can be reduced in the cells in the body. This process may generate Reactive Oxygen Species (ROS) causing lipid peroxidation and oxidative DNA damage. This research was aimed to analyse the influence of chromium to the levels of urinary 8-OHdG as an indicator to support early diagnosis of occupational disease. 66 electroplating workers in Tegal District were taken purposively as samples for this research. There were association between chromium level in urine, malondialdehyde (MDA) level, Body Mass Index, smoking habit, alcohol and supplement drink consumption and urinary 8-OHdG (p<0.05). There was not association between BMI and urinary 8-OHdG (p>0.05). Multivariate analysis using logistic regression showed the alcohol consumption had the most powerful influence to the level of urinary 8-OHdG. The levels of urinary 8-OHdG could be used as an indicator of oxidative DNA damage and early diagnosis of occupational disease among electroplating workers who were exposed by chromium.
Risk Factors of the Incidence of Pulmonary Tuberculosis in Banjarmasin City, Kalimantan, Indonesia Farida Heriyani; Adi Heru Husodo; Yusrizal Djam′an Saleh
International Journal of Public Health Science (IJPHS) Vol 2, No 1: March 2013
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.707 KB)

Abstract

Pulmonary tuberculosis remains a major cause of morbidity and mortality in the world, including Indonesia. In South Kalimantan, an increasing incidence of tuberculosis up to the year 2010 which were taken using a smear-positive reached 3,237 cases, the largest was in Banjarmasin City which reached 642 cases and the detection rate still low, which is 52, 1%. To investigate the relationship among environmental risk factors of the house (residential density, the air temperature, humidity, ventilation, and natural lighting), smoking behavior and alcohol consumption among tuberculosis patients with the incidence of pulmonary tuberculosis in Banjarmasin City. This study was an analytic observational with case control study. The subjects were tuberculosis patients with smear-positive as a case group and smear-negative as a control group. Residential density, the air temperature, ventilation, natural lighting, smoking behavior and alcohol consumption significantly associated with the incidence of pulmonary tuberculosis in Banjarmasin City. While the humidity was not significantly associated. The most dominant risk factors in the incidence of pulmonary tuberculosis in Banjarmasin City were inappropriate of the air temperature in subjects with a history of household contact with tuberculosis patient, natural lighting, and house ventilation.DOI: http://dx.doi.org/10.11591/ijphs.v2i1.1483
Effects of the Occupational Physical Environmental Conditions and the Individual Characteristics of the Workers on Occupational Stress and Fatigue Birowo Herusasongko; Adi Heru Husodo; H A Sudibyakto
International Journal of Public Health Science (IJPHS) Vol 1, No 2: December 2012
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (215.287 KB)

Abstract

This research was conducted to study the effects of environmental factors i.e. heat stress, thermal comfort, and occupational noise and individual factors of the workers i.e. age, work duration (expressed in months), and nutrition status on occupational fatigue and stress. Occupational fatigue was measured using Reaction Timer L-77 Lakassidaya. Occupational stress was measured using questionnaire adapted from Wambrauw (2010). Heat stress and thermal comfort were measured using Questemp 34 Thermal Environment Meter and Lutron AM-4200 Anemometer. Occupational noise level was measured using Lutron SL-4022 Sound Level Meter. Nutrition status was measured using microtoise and body weight scale. Age and work duration was obtained using a personal profile form filled in by each worker. This research employed Structural Equation Modelling (SEM) consisted of direct and indirect effects of exogenous and endogenous variables on endogenous variables. Data analysis was conducted using AMOS 19 software. Data analysis showed that (1) different level of fatigue was indicated on workers working in different work shifts, (2) there was no direct effects of heat stress and  thermal comfort on occupational fatigue, (3) there was a positive direct effect of occupational noise on workers stress but there was no indication that the stress itself has a direct effect on occupational fatigue, thus preventing the indirect effect of occupational noise on occupational fatigue, (4) there was no direct effect of the age of the workers on occupational fatigue, (5) there was a positive direct effect of the workers age on work duration, but the work duration itself did not exhibit any effect on occupational fatigue so therefore no indirect effect of workers age on occupational fatigue was found in this research, (6) and finally, there was a positive direct effect of nutrition status on occupational fatigue.DOI: http://dx.doi.org/10.11591/ijphs.v1i2.1251
Co-Authors Birowo Herusasongko Farida Heriyani H A Sudibyakto Indwiani Astuti Yuliani Setyaningsih Yusrizal Djam′an Saleh