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All Journal JURNAL WIDYA MEDIKA Health Notions AKSONA
Devi Ariani Sudibyo
Departemen Neurologi Fakultas Kedokteran Universitas Airlangga
Dentistry Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Evaluasi Status Fungsional Pasien Stroke Iskemik Di Ruang Rawat Inap Saraf RSUD Dr. Soetomo Menggunakan Instrumen Functional Independence Measure (FIM) Inez Anabela Suprijadi Suprijadi; Florentina Sustini; I Putu Alit Pawana; Devi Ariani Sudibyo
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (589.6 KB) | DOI: 10.33508/jwm.v5i1.1994

Abstract

Introduction: Stroke is a sudden and acute functional focal and global brain disorder that lasts more than 24 hours due to brain blood circulation disorders. Strokes can influence several aspects of life including ADL. Aim: To analyze the patients with ischemic stroke in Neurology Department of RSUD Dr. Soetomo by Functional Independence Measure (FIM) scale at the times of admission to hospital, discharge, and one month after follow-up. Methods: The design of study was cohort. Sample was 60 patients that suitable with the inclusion criteria and was selected by consecutive sampling. Patient’s age, sex, length of stay, nutritional intake, compliance of drugs intake, and the ability of physical activity were recorded. After that, motor assessment and daily activities skills were evaluated by FIM scale. Data was collected by interview and examination for 5 months. Data was analyzed by t-test. Results: A sum of 60 patients are studied. Most frequent genders are male (53,3%), age ranging from 60-69 years old (36,7%), length of stay mostly less than a week (88,3%), nutritional intake is mostly balanced (31,7%), most of the patients take their drugs regularly (66,7%), and most of the patients are only need supervision (45%). The FIM score at admission ranged between 54-71 (40%), at discharged ranged between 72-89 (46,7%), and after one month follow-up ranged between 72-89 (48,3%). There were significant change at p=0,001 between FIM Score at discharged and admission and also between FIM score after one month follow-up and discharged. Conclusion: All patients’ FIM scores were improved. There was a correlation between patient’s length of stay and FIM score at admission and also the ability of physical activity. Significant correlation was found between patient’s age and the ability of physical activity with the FIM score at discharge. Patient’s age, length of stay, and the ability of physical activity have significant correlation with The FIM score after one month follow-up.
The Profile of Pharmacological Treatment in Trigeminal Neuralgia Patients in The Period of January 2018-December 2018 Marlon Yutimma Roestam Moenaf; Maftuchah Rochmanti; Devi Ariani Sudibyo
Health Notions Vol 4, No 9 (2020): September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn40905

Abstract

Trigeminal neuralgia is a condition that affects the trigeminal nerve, that manifests in a series of stabbing like pain, and often described like electricity. Its treatment guideline is to prioritize pharmacotherapy until patient is well. The gold standard treatment for trigeminal neuralgia is pharmacotherapy of Carbamazepine. However, carbamazepine is proven to cause allergic reaction to some patients. This research aims to describe the pharmacotherapy that is given to patients. The regiments of pharmacotherapy in trigeminal neuralgia shows that CBZ is the main pharmacotherapy given, as it is the gold standard treatment. GBP is the is the second most pharmacotherapy given and a concoction medication of Paracetamol, Diazepam and Amitriptyline being the third most favored therapy. Neurotropic B Vitamins plays a big role, as a support in the therapy to maintain the health of the overall nervous system. The pain scale data shows that almost all patients have significant pain relieve. The therapy of trigeminal neuralgia in this study shows that CBZ is most favored as it is the gold standard, however not all AEDs are accessible. Almost all patients have significant pain relieve eventhough not using gold standard treatment. Keywords: trigeminal neuralgia; pharmacotherapy
Injeksi Cairan Dekstrosa Hipertonik (Proloterapi) pada Osteoarthritis Lutut Kronis Muhammad Reza Fathoni; Devi Ariani Sudibyo
AKSONA Vol. 1 No. 2 (2021): JULY 2021
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.762 KB) | DOI: 10.20473/aksona.v1i2.143

Abstract

Pendahuluan: Proloterapi juga dikenal sebagai terapi injeksi regeneratif atau skleroterapi adalah terapi yang menggunakan zat kimia atau biologi untuk kondisi nyeri muskuloskeletal kronis, termasuk osteoartritis lutut. Osteoartritis(OA) lutut adalah bentuk paling umum dari osteoarthritis kronis di seluruh dunia serta merupakan penyebab utama nyeri dan kecacatan dalam beberapa tahun terakhir, hasilbeberapa uji klinis yang dipublikasikan telah menunjukkan efek positif proloterapi pada osteoartritis lutut. Kasus: Wanita,51 tahun dengan nyeri lutut kanan sejak 1 tahun lalu, semakin memberat dalam 3 bulan. Numeric Rating Scale (NRS) adalah 7. Didapatkan tenderness, krepitasi, dan range of movement (ROM) normal tanpa adanya deformitaslutut kanan. Dari pemeriksaan radiologis didapatkan osteoarthritis femorotibial joint grade 1 dan osteoarthritis femoropatellar joint kanan. Injeksi dekstrosa hipertonik 25% dilakukan setiap 2 minggu. Sebelumnya pasien mendapat injeksi steroid intraartikuler (triamsinolon) namun nyeri kembali muncul setelah tiga minggu. Nilai Numeric Rating Scale (NRS) menurun menjadi 4 setelah dilakukan injeksi dekstrosa hipertonik yang keempat. Kesimpulan: Injeksi dekstrosa hipertonik (proloterapi) dapat dijadikan sebagai modalitas terapi alternatif yang menghasilkan perubahan klinis pada osteoarthritis lutut dengan resiko minimal, biaya terjangkau dan penggunaan yang mudah.  
Azathioptrine in Refractory Tolosa-Hunt Syndrome: Two Case Report Devi Ariani Sudibyo; Mohammad Saiful Ardhi
AKSONA Vol. 2 No. 1 (2022): JANUARY 2022
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (266.809 KB) | DOI: 10.20473/aksona.v2i1.186

Abstract

Introduction: Tolosa-Hunt syndrome (THS) is an inflammatory disease with painful ophthalmoplegia and unilateral periorbital headache as detailed by the International Classification of Headache Disorders, 3rd edition (ICHD-3). Azathioprine has been suggested as a second-line treatment in refractory THS when oral corticosteroid only gives a partial response. Case: Two cases of THS, 45-year-old and 41-year-old women with unilateral headache, drooping of the left upper eyelid, and diplopia. They presented with complete ophthalmoplegia and ophthalmic division of trigeminal nerve disturbance. Magnetic resonance imaging (MRI) showed thickening of the left cavernous sinus, suggesting THS, while the other was normal. Corticosteroid (prednisone 1-1,5 mg/day) was given orally for the first two weeks, and according to the Numeric Pain Rating Scale (NPRS), pain intensity was reduced from severe to moderate. As a second-line treatment, azathioprine (2 mg/kg/day) was given afterward, with a significant reduction in pain intensity and remission of ophthalmoplegia within seven days. Azathioprine was used as an immunosuppressive agent and was continued for another three months without any deterioration in neurological deficits. The levels of complement 3, 4 (C3, C4), and C-reactive protein (CRP) were normal in both patients, with a slight increase in erythrocyte sedimentation rate (ESR) and equivocal values on antinuclear antibody (ANA) results. Other differentials of THS were eliminated from history-taking, physical examination, and proper investigations. Conclusion: Azathioprine as a second-line treatment can be used instead of an oral corticosteroid for refractory cases of THS with fewer side effects. Complete remission of ophthalmoplegia and a significant reduction in pain intensity was obtained.
Co-Authors Florentina Sustini Inez Anabela Suprijadi Suprijadi Maftuchah Rochmanti Marlon Yutimma Roestam Moenaf Mohammad Saiful Ardhi Muhammad Reza Fathoni Pawana, I Putu Alit