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All Journal International Journal of Public Health Science (IJPHS) Farmasains : Jurnal Ilmiah Ilmu Kefarmasian JCPS (Journal of Current Pharmaceutical Sciences)
Sabtanti Harimurti
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Health Professions Medicine & Pharmacology

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A Review of The Anti-diabetic Activity of Andrographis paniculata (Burm. f.) Nees based in-vivo Study Titi Komalasari; Sabtanti Harimurti
International Journal of Public Health Science (IJPHS) Vol 4, No 4: December 2015
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (235.666 KB) | DOI: 10.11591/ijphs.v4i4.4743

Abstract

Diabetes mellitus (DM) is ricing nowadays. DM is a metabolic deasease characterized by increasing of glucose blood level for prolonged time. Patient with DM must take medicine for lowering glucose levels in whole life. Synthetic anti-diabetic agent is commonly used and significantly able to maintain the glucose blood levels. However, many side effects will occur during the treatment. Further, people is trying to find an alternative medicine for DM treatment. This paper will discuss about an alternative medicine for anti-diabetic agent that is called Andrographis paniculata (Burm. f.) Nees based in-vivo study. Search data obtained from PubMed, PMC (PubMed Central), International Food and Research Journal, and Google search engine. Inclution and exclution criteria were used for selection of journals. Inclution criteria were taken is in-vivo study of Andrographis paniculata as anti-diabetic, published in 2000-2014, and free full text journal or PubReader (full text journal in PubMed Central) in English or Indonesian language. Base on reviewed journals that was conducted, anti-diabetic agent of Andrographis paniculata was found in extract, in fractional coumpund (i.e. andrographolide or its analogue AL-1: andrographolide-lipoic acid), and in combination with synthetic drug or other herbal. Therefore, Andrographis paniculata is potentially developed as an alternative anti-diabetic agent.
Analisis Kualitatif dan Kuantitatif Kandungan Boraks Pada Bakso Tusuk di Wilayah Kabupaten Gunungkidul Provinsi Daerah Istimewa Yogyakarta Sabtanti Harimurti; Asep Setiyawan
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 6 No. 2 (2019)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (586.281 KB) | DOI: 10.22236/farmasains.v6i2.2855

Abstract

Makanan adalah salah satu sumber energi bagi tubuh manusia. Makanan yang baik adalah makanan yang memiliki tingkat gizi yang tinggi sehingga berpengaruh pada kualitas kesehatan manusia. Salah satu makanan yang sedang digemari dan sering ditambahkan zat berbahaya adalah bakso tusuk. Penelitian ini dilakukan untuk mengetahui seberapa lama bakso tusuk dapat dikonsumsi dan disimpan pada suhu ruang dan mengetahui ada tidaknya kandungan boraks pada bakso tusuk serta mengukur kadar boraks pada bakso tusuk di wilayah Kabupaten Gunungkidul, Provinsi Daerah Istimewa Yogyakarta. Jenis penelitian yang digunakan adalah deskriptif laboratorik dengan pemeriksaan laboratorium secara kualitatif dengan metode pembusukan, uji warna kertas tumerik dan nyala api sedangkan secara kuantitatif dengan metode titrasi asam basa. Teknik pengambilan sampel pada penelitian ini adalah cluster sampling. Hasil analisis kualitatif dan kuantitatif menunjukan seluruh sampel bakso tusuk di Kabupaten Gunungkidul Provinsi Daerah Istimewa Yogyakarta, positif mengandung boraks. Kadar boraks berkisar antara 0,34%–3,41%.
PENINGKATAN KEMAMPUAN ANTIOKSIDAN PADA KRIM KULIT JERUK NIPIS (Citrus aurantifolia S) MENGGUNAKAN VCO DENGAN METODE DPPH Dyani Primasari Sukamdi; Sabtanti Harimurti; Kunniya Amany; Vella Lailli Damarwati
JCPS (Journal of Current Pharmaceutical Sciences) Vol 7 No 2 (2024): March 2024
Publisher : LPPM - Universitas Muhammadiyah Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Lime peel (Citrus aurantifolia S.) is rich in flavonoids, tannins, and coumarins so that it can act as an antioxidant. It can be formulated with Virgin Coconut Oil (VCO) into a cream to protect the skin and prevent aging. This study aims to determine the antioxidant activity of cream preparations containing lime peel extract with DPPH method and to determine whether the concentration of VCO can affect the physical evaluation and antioxidant activity of cream preparations. Lime peel was extracted by maceration method using 96% ethanol and cream were made using various VCO concentrations (30%, 35% and 40%). The three formulas were physically tested to determine the effect of adding VCO concentration to the physical quality of the cream. Data analysis was carried out using the One-Way Anova method and the results of the adhesive power test, dispersion and pH concluded that the significance was, therefore the addition of VCO concentration does not affect the value on adhesion, spread ability and pH. The IC50 results obtained for formulas I, II and III are 31.78 ppm, respectively; 29.64 ppm ; 26.95 ppm. Data was statistically tested using One-Way Anova, the results showed that lime peel extract cream with the addition of VCO affected antioxidant activity in cream preparations. Where the greater the concentration of VCO used in lime peel cream, the greater the antioxidant activity. Keywords : Lime peel, cream, extract, VCO, antioxidants
Co-Authors Asep Setiyawan Dyani Primasari Sukamdi Kunniya Amany Titi Komalasari Vella Lailli Damarwati