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Immunoinformatics Analysis of SARS-CoV-2 Isolated from Karst of Bats in Malang, Indonesia Moch Irfan Hadi; Aditya Sukma Prawira; Khuliyah Candraning Diyanah; Dedy Suprayogi; Soedjajadi Keman; Yudied Agung Mirasa; M Yusuf Alamudi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14805

Abstract

In December 2019, cases of mysterious pneumonia were first reported in Wuhan, Initially, the diseasewas temporarily named as 2019 novel coronavirus (2019-nCoV), then WHO announced a new name onFebruary 11, 2020, namely Coronavirus Disease (COVID-19) which is caused by a virus Severe AcuteRespiratory Syndrome Coronavirus-2 (SARS-CoV-2). This virus can be transmitted from person toperson and has spread widely in China and more than 190 other countries and territories. Meanwhile inIndonesia, up to September 2020, 203 thousand cases of COVID-19 were found and 8336 deaths. Batsact as important disease reservoirs for various etiologic agents of disease that can be transmitted betweenspecies, infecting humans and mammals, both domestic and wild. The purpose of this study was to analyzeSARS-CoV-2 immunoinformatics in bats in Karst Malang Indonesia as the basis for making SARS-CoV-2vaccines. This research method is SARS-CoV-2 amino acid bats in Karst Malang, Indonesia analyzed byimmunoinformatics. From the research results, it was found that SARS-CoV-2 protein from Malang Karstbats were antigen, non-allergen and non-toxin, so that they could be used as vaccine candidates, diagnostickits and immunotherapy.
The Effectiveness Of Techniques Of Cradle Hold And Football Hold Lowing On The Event Of Labet Milk Clothing In The Principal Mother Year 2023 Rut Kowi; Eko Winarti; Yudied Agung Mirasa
Student Scientific Journal Vol 1 No 2 (2023): Juli
Publisher : Universitas Dehasen Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (298.567 KB)

Abstract

Breastfeeding is the most ideal nutrition for the growth and development of infants. But usually there is a problem when mothers breastfeed their babies, which is related to improper breastfeeding techniques, which can cause blisters on the nipple. Researchers aim to find out the difference in effectiveness of thetechniques breastfeeding cradle hold and football hold on the incidence of blisters on post partum mothers at BPM Naomi In kertomananggal village, gayungan district, wonokromo district.Design of this study is the correlation with theapproach causal design.The population in this study amounted to 36 respondents with a sample size of 36 respondents. Sampling of this study uses total sampling, data collection using observation sheets. The results showed there were differences in the effectiveness of the Credle Hold technique on the incidence of blisters on nipple mothers. The majority (77.8%) of respondents withBreastfeeding Techniques Cradle Hold Against the Occurrence of Blisters on Postpartum Mothers, and a small portion (22.2%) of respondents with theBreastfeeding Technique of Football Hold Blisters.test results Chi square Breastfeeding Technique Cradle Hold Against the Occurrence of Blisters on the Mother obtained p value = 0.047 (<0.05), correlation coefficient 0.479 which means H1 is accepted or there is a relationship, while theBreastfeeding Technique Football Hold Against the Occurrence of Blisters on the Mother is obtained p value = 0.294 (> 0.05) which means there is no relationship. The conclusion of the Cradle Holdbreastfeeding technique research is more effective on the incidence of blisters on post partum mothers at BPM Sri Ani Pelem Village, Campurdarat District, Tulungagung Regency, For this reason, it is expected that postpartum mothers should use the Cradle Hold technique while breastfeeding.
The Effectiveness Of Techniques Of Cradle Hold And Football Hold Lowing On The Event Of Labet Milk Clothing In The Principal Mother Year 2023 Mariance Aiba; Eko Winarti; Yudied Agung Mirasa
Student Scientific Journal Vol 1 No 2 (2023): Juli
Publisher : Universitas Dehasen Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.361 KB)

Abstract

Background: Hormonal contraceptives are the type that is more widely used because of how it works, it is effective, practical, the price is relatively cheap and practical. However, long-term use of injectable contraceptives can cause changes in serum lipids, cause vaginal dryness, decrease libido, emotional disturbances, headaches, acne and can reduce bone density. Research Objectives: To describe what factors influence mothers in choosing injectable contraception. Methods: This type of research is a descriptive study with a cross sectional approach that provides an overview of the factors that influence mothers in choosing injectable contraception. The population in this study were all users of injectable contraceptives at the Amban Health Center in January - April 2020 using the Sampling Technique. Data analysis using the Proportion formula. Results: Age factor < 35 years was 30 (93.75%), experience with past contraceptives was 22 (68.75%), health status without a medical history was 19 (59.38%), side effects experienced side effects amounted to 28 (87.5%). Conclusion: The dominant factor influencing mothers to use injectable family planning is the age factor.
Relationship Between Adherences of Antiretroviral (ARV) Consumption with Viral Load in HIV/AIDS Indah Jayani; Susmiati Susmiati; Yudied Agung Mirasa; Khusnul Khotimah
Journal for Quality in Public Health Vol. 5 No. 1 (2021): Journal for Quality in Public Health
Publisher : Master of Public Health Program Institut Ilmu Kesehatan STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/jqph.v5i1.255

Abstract

Viral load testing is an informative and sensitive method for successful HIV / AIDS therapy. This study aims to determine the relationship between adherence to viral antiretroviral consumption and viral load in people with HIV/AIDS. This research is a correlational analytic study using a cross-sectional approach. The population in this study was 34 people and, the number of samples was 32 using the purposive sampling technique. The research sample in this study was 32 respondents. The test results using the Spearman Rank obtained p-value 0,00 > 0,05. It was concluded that there was a relationship between adherence to antiretroviral drugs and viral load. Advice for people with HIV / AIDS is expected to increase adherence to ARV consumption so that viral load is low and undetectable so that CD4 cell count increases and disease prognosis improves.