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All Journal Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi JCES (Journal of Character Education Society) ad-Dawaa : Journal of Pharmaceutical Sciences
Ahmad Najib
Fakultas Farmasi Universitas Muslim Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Journal : As-syifaa Jurnal Farmasi

 1 
PENGEMBANGAN TARGET TERAPI PADA HEPATITIS C Ahmad Najib
As-Syifaa Jurnal Farmasi Vol 1, No 2 (2009): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v1i2.102

Abstract

For the development of new, specific anti-HCV drugs, an understanding of the HCV life cycle in particular the genomic organization and polyprotein processing, is essential. It has resulted in the development of several agents that target specific stages of the life cycle, the so-called specifically targeted antiviral therapy for HCV (STAT-C) drugs. Potential processes for viral inhibition include virus entry into the host cell, proteolytic processing, RNA replication, and the assembly and release of the new virions. Among the most promising new agents in development are the protease and polymerase inhibitors, as discussed below. RNA-targeted therapies, such as antisense oligonucleotides, ribozymes and small interfering RNA (siRNA)-targeting structures, have shown substantial success at inhibiting the HCV life cycle in vitro, but not in vivo. The structural viral envelope proteins E1 and E2, as well as their assembly, represent other potentialantiviral targets. Analogous to a recently developed HIV cell fusion inhibitor, detailed understanding of HCV cell fusion and cell entry could permit the development of specific HCV entry inhibitors.Key Word : HCV, Antiviral, Target Specific
PEMERIKSAAN FARMAKOGNOSTIK DAN PROFIL KROMATOGRAFI LAPIS TIPIS TUMBUHAN SARANG SEMUT (Myrmeco diapendans Merr. & Perry) ASAL KABUPATEN TELUK BINTUNI PAPUA BARAT Abd Kadir; Ahmad Najib; Fazlur Rachman
As-Syifaa Jurnal Farmasi Vol 4, No 2 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (378.368 KB) | DOI: 10.33096/jifa.v4i2.83

Abstract

Pharmacognostic assay and Profile of  Thin Layer Chromatography Myrmecodia Plant (Myrmecodia pendens Merr & Perry) from Bintuni Bay, west Papua. Morphologycal Identification showed that Myrmecodia Plant (Myrmecodia pendens Merr & Perry) include magnoliopsida class with steep root system. Leaf anantomy from the leaf showed that anomositic type stomata.Powder extracbility of Myrmecodia Plant (Myrmecodia pendens Merr & Perry) including total ash is 33,92% and insoluble acid ash is 7,78%. While in the water soluble extractive 15,09% and aethanol soluble extractive 5,40%. Chemical identification on the tuberous powder showed that it is consist of tannin (pirogalotanin) and flavanoid. Profile of  Thin layer chromatography obtained total spot more diethyl ether extract equel to 8 spot and n-butanol extract equal to 5 spot with n-hexene : ethyl acetate (8:2( and Chloroform : methanol : water (10:6:0,5).Key words : Pharmacognostic, Myrmecodia pendens, Thin layer chromatography
ISOLASI DAN IDENTIFIKASI KOMPONEN KIMIA FRAKSI n-HEKSANA DAUN TUMBUHAN JERINGAU (Acorus calamus Linn.) Ari Wahyuni; Abd Kadir; Ahmad Najib
As-Syifaa Jurnal Farmasi Vol 4, No 1 (2012): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (231.22 KB) | DOI: 10.33096/jifa.v4i1.143

Abstract

Isolation and identification of n-Hexane faction from Sweet Flag leaves (Acorus calamus Linn.) was done. The aim of research is determine the chemical compound on it leaf, which was commonly used as the traditional medicine. Sample from 250 grams of dried Sweet Flag leaf, macerate using methanol, produce 21.563 grams dried extract. Isolation of n-hexane faction  using  column  chromatography  method  with  various  mobile  phases.  The  isolate identified by UV and IR spectroscopy method. From the data result show that the isolate has a specific compound.Key words : Isolation, Acorus calamus, UV-Vis, IR
Co-Authors A Amaliah Dahlia A. Trihadi Kusuma Abd Kadir Abd. Malik Abdullah Mahmud Aktsar Roskiana Ahmad Andi Adelah Andi Herlinda Ari Wahyuni Asni Amin Aswar Aswar Bafadal, Mentarry Fazlur Rachman Hamidu, La Izzatul Fikril Mujtahid Linda Erviana Nur Rezky Khairun Nisaa Nurhawa Vitalia Nurul Purnama Wati Rais Razak Reni Fauziah Rezki Amriati Syarif Rezki Amriati Syarif Risda Waris Risda Waris Risda Waris Saida I. Suradji Selpida Handayani Siti Sya'diyah Virsa Handayani, Virsa Zainal Abidin