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All Journal Health Care : Jurnal Kesehatan The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Leonardo Basa Dairy
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Health Professions Medicine & Pharmacology Nursing Public Health

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Hubungan Higiene Perorangan Dengan Penyakit Demam Tifoid di Rumah Sakit Umum Bethesda Kota Gunungsitoli Miter Elidanovan Harefa; Leonardo Basa Dairy; Jenny Novina Sitepu; Sisca Silvana
HEALTH CARE : JURNAL KESEHATAN Vol 11 No 1 (2022): Health Care : Jurnal Kesehatan
Publisher : STIKes Payung Negeri Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36763/healthcare.v11i1.190

Abstract

Penelitian ini bertujuan untuk mengetahui hubungan higiene perorangan dengan penyakit Demam Tifoid di Rumah Sakit Umum Bethesda Kota Gunungsitoli. Desain penelitian merupakan analitik observasional dengan desain case control. Responden terdiri dari kelompok kasus yaitu pasien yang dilaporkan terkena penyakit demam tifoid dan kelompok kontrol yaitu pasien tidak dilaporkan terkena penyakit demam tifoid, dengan teknik consecutive sampling. Lokasi penelitian di Rumah Sakit Umum Bethesda Kota Gunungsitoli bagian rawat inap. Data responden diperoleh saat pengisian kuesioner dan mengetahui status pasien lewat hasil rekam medik pemeriksaan Uji TUBEX®. Analisis data di olah dengan memakai program lunak komputer secara univariat dan bivariat. Hasil analisis univariat menunjukkan responden yang kurang baik lebih banyak pada kebiasaan mencuci tangan sebelum makan (52%) dan kebiasaan makan atau jajan di luar rumah (72%), sedangkan yang baik lebih banyak pada kebiasaan mencuci tangan setelah buang air besar (68%) dan kebiasaan mencuci bahan makanan mentah sebelum dikonsumsi (70%). Hasil analisis bivariat dengan uji chi square menemukan bahwa terdapat hubungan yang bermakna antara kebiasaan mencuci tangan sebelum makan dengan penyakit demam tifoid dengan nilai p-value sebesar 0,024 (P<0,05) dan tidak terdapat hubungan yang bermakna antara kebiasaan mencuci tangan setelah buang air besar dengan penyakit demam tifoid dengan nilai p-value sebesar 0,225 (P>0,05). Hasil analisis bivariat dengan uji fisher exact menemukan bahwa terdapat hubungan yang bermakna antara kebiasaan makan atau jajan di luar rumah dengan nilai p-value sebesar 0,000 (P<0,05) dan terdapat hubungan yang bermakna antara kebiasaan mencuci bahan makanan mentah sebelum dikonsumsi nilai p-value sebesar 0,012 (P<0,05).
Level of Gastrin Serum and Ulcer Size on Gastric Ulcer Correlated to Helicobacter pylori Infection Dasril Efendi; Rustam Effendi; Leonardo Basa Dairy; Juwita Sembiring; Betthin Marpaung; Mabel Sihombing; Sri Maryuni Soetadi; Lukman Hakim Zain
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 10, NUMBER 3, December 2009
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/1032009113-116

Abstract

Background: Previously has been defined that peptic ulcer has strongly correlated to Helicobacter pylori (H. pylori) infection. But it hasn’t determined about correlation of gastrin serum level to the ulcer severity on H. pylori infection. The aims of this study were to find the percentage of H. pylori infection on peptic ulcer cases and its correlation to the gastrin serum level. Method: This is analytic cross sectional study in 50 patients with gastric ulcer who came to Adam Malik hospital from February to October 2007. The correlation between gastrin serum level and the size of ulcer with positive and negative Urea Breath Test (UBT) group was analyzed by unpaired student t- test. The correlation between gastrin serum level and ulcer size were investigated with Pearson correlation test and linier regression. Result: Fifty eligible patients, 33 (66%) had positive UBT and 17 (34%) were negative. There were statistically significant difference on gastrin serum level in positive UBT and negative respectively (p = 0.017). There were also significant difference between mean of ulcer size in positive UBT and negative respectively (p = 0.025). There were correlation between gastrin serum level and ulcer size (r = 0.315; p = 0.026). It can predict the increasing ulcer size in 0.012 mm every 1 pg/mL of gastrin serum elevated. Conclusion: Patients with positive UBT has greater ulcer size and higher gastrin level as compared to the negative group. There were positive correlation between gastrin serum level to the size of ulcer in peptic ulcer patients and increase of ulcer size followed with elevated of gastrin serum level. Keywords: Helicobacter pylori infection, gastrin serum level, ulcer size
Aspartate Aminotransferase to Platelet Ratio Index and FibroScan for Predicting Liver Fibrosis with Chronic Hepatitis B Elias Tarigan; Rustam Effendi Yusuf; Leonardo Basa Dairy; Juwita Sembiring; Mabel HM Sihombing; Gontar Alamsyah Siregar; Lukman Hakim Zain
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 3, December 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (533.298 KB) | DOI: 10.24871/1432013139-144

Abstract

Background: Non-invasive test have been constructed and evaluated mainly for binary diagnoses. The accuracy of non-invasive tests such as aspartate aminotransferase to platelet ratio index (APRI) and transientelastography/FibroScan should be evaluated especially in clinical practice. The aim of the study was to evaluate the accuracy of detailed fibrosis classification available for APRI and FibroScan to liver biopsy in chronichepatitis B patients.Method: A cross sectional study was conducted in 51 patients with chronic hepatitis B. The patients underwent laboratory test, FibroScan and liver biopsy between April 2011 and July 2013 at Adam Malik Hospital, Medan.Liver biopsy was assessed based on the METAVIR score. Area under receiver operating characteristic curve (AUROC) predictive value was used to evaluate the accuracy of APRI and FibroScan. All data were analyzedusing SPSS 20.0.Results: APRI versus METAVIR diagnosed severe fibrosis and cirrhosis with sensitivity 40% and specificity 83.9%, positive predictive value (PPV) 61.5%, negative predictive value (NPV) 68.4%, positive likelihood ratio(LR) 2.48 and negative LR 0.72 with diagnostic accuracy 66.7%. The AUROC value was 0.619 (95% CI = 0.446 – 0.715); kappa = 0.255; p 0.05. FibroScan versus METAVIR predictive value with sensitivity 75% andspecificity 67.6% were PPV 60%, NPV 67.7%, positive LR 2.31 and negative LR 0.36 with diagnostic accuracy 70.6%. The AUROC value was 0.714 (95% CI = 0.567–0.861); kappa 0.409; p 0.05.Conclusion: FibroScan has better accuracy than APRI for predicting severe fibrosis and cirrhosis in patientswith chronic hepatitis B.Keywords: APRI, FibroScan, liver biopsy, chronic hepatitis B
S-Index and APRI Score to Predict Liver Fibrosis Chronic in Hepatitis B and C Patients Elias Tarigan; Leonardo Basa Dairy; Juwita Sembiring; Mabel Sihombing; Gontar Alamsyah Siregar; Lukman Hakim Zain
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 2, August 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (389.107 KB) | DOI: 10.24871/142201364-68

Abstract

Background: A great interest has been dedicated to the development of non invasive predictive models in recent years to substitute liver biopsy for fibrosis assessment and follow-up. The aim of this study was to comparethe accuracy between S-index and aspartate aminotransferase to platelet ratio index (APRI) to FibroScan for predicting liver fibrosis in chronic hepatitis B and C patients.Method: A cross-sectional study was conducted in 40 patients with chronic hepatitis B and C between January 2010 - May 2011 at Division of Gastroentero-hepatology, Department of Internal Medicine, Adam Malik Hospital, Medan. Patients underwent laboratory examination and FibroScan, then used predictive values to assess the accuracy of S-index scores and APRI compared to FibroScan. The analysis was performed using SPSS 15.0.Results: S-index identified significant fibrosis in 87.5% patients with sensitivity (Se) 87.5% and specificity (Sp) 100%. About 67.5% of 40 patients could be identified correctly. S-index also could accurately predict the absence or presence of cirrhosis in 87.5% of the total 40 patients, with NPV 91.7% and PPV 81.25%, respectively. APRI for significant fibrosis has Se 85.7%, Sp 88%, PPV 88.8%, NPV 69.2%; while Se 53%, Sp 88%, PPV 72.7%, NPV 75.8% for liver cirrhosis. AUROC value for S-index was higher than APRI in predicting significant fibrosis and cirrhosis, i.e. 0.938 vs. 0.917 and 0.873 and 0.707, respectively.Conclusion: The S-index has a higher accuracy than APRI in predicting significant fibrosis and cirrhosis in patients with chronic hepatitis B virus and hepatitis C virus infection.Keywords: S-index, APRI score, FibroScan, chronic hepatitis B and C
Profile of Colorectal Cancer Patients in Endoscopic Unit at Dr. Pirngadi Hospital - Medan Rustam Effendi; Dasril Efendi; Leonardo Basa Dairy; Juwita Sembiring; Mabel Sihombing; Betthin Marpaung; Sri Maryuni Soetadi; Gontar Alamsyah Siregar; Lukman Hakim Zain
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 9, ISSUE 3, December 2008
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/93200878-81

Abstract

Background: Colorectal cancer is the third most prevalent cancer and the second leading cause of cancer death worldwide every year. Rates of this malignancy vary by country. In Indonesia, the prevalence is estimated to have an increased tendency. The objectives of this sudy was to examine the prevalence and profile of colorectal cancer, which are diagnosed by endoscopic examination. Method: The study was conducted retrospectively, by examining the Result of endoscopic findings of patients with rectal bleeding, altered bowel habit, chronic diarrhea, unexplain abdominal pain, and other signs and symptoms at The Endoscopic Unit Department of Internal Medicine, Dr. Pirngadi hospital from January 2004 to June 2008. Results: We found 197 patients with colorectal cancer (CRC) from 760 patients examined by colonoscopy (25.9%). One hundred and one patients (51.3%) out of 197 CRC patients were female. Most were in the group of age 51-60 years (28.9%). The most frequent ethnic of the patients were Bataknese (46.2%). The most common symptom was rectal bleeding (70.6%). The most common location of CRC was in the rectum (74.6%). Histopathologic Result was adenocarcinoma. Conclusion: The prevalence of colorectal cancer in this study were twenty six percents. Rectal bleeding appeared to be the most common sign in this study. Rectum was the most common site of the cancer. Most of patients were Bataknese. Patients were at advanced stage and most of them were having well-differentiated adenocarcinoma.   Keywords: colorectal cancer, rectal bleeding, altered bowel habits, colonoscopy
Co-Authors Betthin Marpaung Dasril Efendi Elias Tarigan Gontar Alamsyah Siregar Gontar Alamsyah Siregar Jenny Novina Sitepu Juwita Sembiring Lukman Hakim Zain Mabel HM Sihombing Mabel HM Sihombing, Mabel HM Mabel Sihombing Miter Elidanovan Harefa Rustam Effendi Rustam Effendi Rustam Effendi Yusuf Rustam Effendi Yusuf, Rustam Effendi Sisca Silvana Sri Maryuni Soetadi