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Anak Agung Gde Oka Darmayudha
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Pengaruh Pemberian Ekstrak Etanol Daun Ashitaba Terhadap Histopatologi Lambung Mencit Jantan (THE EFFECT OF ETHANOL EXTRACT OF ASHITABA LEAVES TOWARD THE GASTRIC HISTOPATHOLOGY OF MALE MICE) I Putu Wiralaga; I Wayan Sudira; I Made Kardena; Anak Agung Gde Oka Darmayudha
Buletin Veteriner Udayana Vol. 7 No. 1 Pebruari 2015
Publisher : The Faculty of Veterinary Medicine, Udayana University

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Abstract

This study was intended to find out the effect of ethanol extract of Ashitaba leaves (Angelicakeiskei) toward the gastric histopathology of male mice. After being adapted for one week, 25 malemice (Mus musculus) were divided randomly to be five treatments. The first treatment was not given ethanol extract of Ashitaba leaves as control. The second till fourth treatment was given eachdose of 125; 250; 500; dan 1,000 mg/kg bb during 21 days orally. Necropsy for gastric organharvesting was conducted on the day of 22. The result of giving ethanol extract of Ashitaba leaves(Angelica keiskei) with a dose of 125 mg/kg bb showed that three mice undergo degeneration andinfiltration of inflammatory cells and one mice undergo necrosis. The dosing of 250 mg/kg bbshowed that three mice undergo degeneration and two mice undergo infiltration of inflammatorycells and necrosis as well. The dosing of 500 mg/kg bb showed that three mice undergodegeneration, infiltration of inflammatory cells, and necrosis. The dosing of 1,000 mg/kg bbshowed that three mice undergo degeneration and necrosis, and four mice undergo infiltration ofinflammatory cells. Based on the results of the study, It was concluded that the ethanol extract ofleaves Ashitaba dose of 125 mg / kg bw up to 1,000 mg / kg bw for 21 days did not cause structural disorders of the stomach organ histopathology of mice (Mus musculus) male. 
Profil Hematologi Mencit Pasca Pemberian Jamu Temulawak Secara Oral (HEMATOLOGICAL PROFILE IN MICE WITH ORAL ADMINISTRATION OF JAMU TEMULAWAK) Robby Deddy Septianto; Ida Bagus Komang Ardana; I Wayan Sudira; Anak Agung Gde Oka Darmayudha
Buletin Veteriner Udayana Vol. 7 No. 1 Pebruari 2015
Publisher : The Faculty of Veterinary Medicine, Udayana University

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Abstract

The purpose of this study to assess changes in hematological profile (leucocyte differential,total leukocytes and platelets) mice with oral administration of jamu temulawak. 25 male miceaged 12 weeks, each weighing 30 g were divided into five groups and five replications. P0 suchdoses given as a control (0 mg/100 g), P1 (10 mg/100 g), P2 (20 mg/100 g), P3 (30 mg/100 g), andP4 (40 mg/100 g). Differential leukocytes, total leukocytes and platelets of mice, using the SysmexHematology analyzer showed oral administration of jamu temulawak was highly significant  to total leukocytes and significantly  on lymphocytes of mice, whereas the total platelets, eosinophils,neutrophils, basophils and monocytes showed no significant difference, but the effect is happeningis within normal limits. Thus giving jamu temulawak can be used to maintain animal healthassociated with hematologic profiles.
Perbandingan Anestesi Xylazin-Ketamin Hidroklorida dengan Anestesi Tiletamin- Zolazepam terhadap Frekuensi Denyut Jantung dan Pulsus Anjing Lokal Anak Agung Gde Oka Darmayudha; I Wayan Gorda
Buletin Veteriner Udayana Vol. 4 No.1 Pebruari 2012
Publisher : The Faculty of Veterinary Medicine, Udayana University

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Abstract

A study to determine the effect of anesthesia xylazine- ketamine hydrochlorida withanesthesia tiletamine-zolazepam administration to heart pulse frequency and pulse duringanesthetion. The experimental was carried duct on local dog. The experimental design usewas a splite in time with 2 treatment : treatment I xylazin-ketamin ( 2 mg/Kg Body weightof xylazine ; 15 ing/Kg Body weight ketarnine) and treatment II tiletamine-zolazepam ( 20mg/Kg Body weight). Each treatment use 5 dogs as refrain so we use 10 dogs for all of thetreatment. Obtain data is analized by various investigated test. Result of this study indicatedthat difference of treatment there were no significance, but time of the observed duringanesthesion showed more highly significance and significant to pulse frequency.
Co-Authors I Made Kardena I Putu Wiralaga I Wayan Gorda I Wayan Sudira Ida Bagus Komang Ardana Robby Deddy Septianto