Article Per Year (5 Year)
p-Index From 2019 - 2024
0.61
P-Index
This Author published in this journals
All Journal Health Notions Majalah Farmasetika International Journal of Science and Environment
Gabriella Septiani Nasution
Politeknik Kesehatan Kemenkes
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions Mathematics Medicine & Pharmacology Nursing Physics Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Sputum Conversion is Faster with Vitamin D Suplementation in Pulmonary TB Patients Nita Andriani Lubis; Gabriella Septiani Nasution
Health Notions Vol 3, No 11 (2019): November
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.267 KB) | DOI: 10.33846/hn31103

Abstract

Pulmonary tuberculosis (TB) is still a problem that must be resolved in Indonesia, especially North Sumatra. The study aims to determine the effect of vitamin D supplementation on the speed of sputum conversion in pulmonary TB patients. Randomized controlled trial study was conducted on 41 pulmonary TB patients according to inclusion criteria. Research subjects were given TB drug (DOTS program) and vitamin D treatment for 2 months. Sputum examination based on smear was carried out microscopically at 2nd week, 4nd week, 6nd week, and 8nd week after treatment. The results showed that all pulmonary TB patients who were given the intervention experienced sputum conversion. Research subjects with AFB +1 occurred the fastest conversion compared to the others. Statistical analysis using chi square obtained significant results (p = 0.0001). Sputum conversion evaluation based on the initial AFB status, there was a significant relationship between the time of sputum conversion with the initial AFB status with a very strong correlation level (r = 0.767). Vitamin D has been shown to have a significant effect on the patient's sputum conversion. Keywords: pulmonary TB; vitamin D; sputum conversion
Uji Antiseptik Sabun Cair Ekstrak Daun Lantana camara L. Terhadap Pertumbuhan Staphylococcus sp. Melia Sari; Adek Chan; Gabriella Septiani Nasution; Dewi Kristiani Mendrofa
Majalah Farmasetika Vol 7, No 3 (2022): Vol. 7, No. 3, Tahun 2022
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v7i3.37876

Abstract

Daun saliara (Lantana camara L.) termasuk gulma tahunan berbentuk perdu, berkayu dan berakar tunggang. Daun saliara mengandung senyawa aktif minyak atsiri, flavonoid, alkaloid, tanin, saponin merupakan senyawa yang bersifat sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui ekstrak etanol daun saliara dapat diformulasikan dalam bentuk sediaan sabun cair dan memiliki aktivitas antibakteri terhadap Staphylococcus aureus dan Staphylococcus epidermidis. Penelitian ini bersifat eksperimental yaitu ekstrak etanol daun saliara (Lantana camara L.) dengan konsentrasi 3%, 6% dan 9% dan dilakukan uji sifat fisik sediaan dengan uji organoleptis, uji homogenitas, uji pH, uji tinggi busa, uji viskositas dan uji aktivitas antibakteri. Pembuatan sediaan sabun cair ekstrak etanol daun saliara (Lantana camara L.) konsentrasi 3%, 6% dan 9% memenuhi kriteria uji organoleptis bewarna hijau dan tekstur cair, uji homogenitas menunjukkan sediaan homogen, uji pH sabun cair yaitu 8-9, uji tinggi busa yaitu 53-86 mm, uji viskositas 1073-2890 cps dan uji aktivitas antibakteri Staphylococcus aureus dengan konsentrasi 3%, memiliki daya hambat 5 mm, konsentrasi 6% memiliki daya hambat 5,5 mm dan konsentrasi 9% memiliki daya hambat 6 mm. Sedangkan pada uji aktivitas terhadap bakteri Staphylococcus epidermidis dengan konsentrasi 3% memiliki daya hambat 5 mm, konsentrasi 6% memiliki daya hambat 6 mm dan konsentrasi 9% memiliki daya hambat 7 mm. Berdasarkan hasil tersebut dapat disimpulkan bahwa sabun cair ekstrak etanol daun saliara (Lantana camara L.) memiliki daya hambat terhadap pertumbuhan bakteri Staphylococcus aureus dan Staphylococcus epidermidis.
Toxicity Test of Catharanthus roseus Flower Extract with Brine Shrimp Lethality Test Method Melia Sari; Chemayanti Surbakti; Tetty Noverita Khairani; Willy Novita Sari; Gabriella Septiani Nasution
International Journal of Science and Environment (IJSE) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (248.402 KB) | DOI: 10.51601/ijse.v2i1.12

Abstract

Tapak dara (Catharanthus roseus) is a plant belonging to the Apocynaceae family originating from Central America and is generally grown as an ornamental plant. The purpose of this study was to determine the percentage of mortality data and the LC50 value of tapak dara methanol extract (Catharanthus roseus) against Artemia salina Leach larvae using the Brine Shrimp Lethality Test (BSLT) method. The BSLT method used consisted of 6 concentration treatments, namely 20 ppm, 60 ppm, 100 ppm, 140 ppm, 180 ppm, and 0 ppm a negative control, each of which was repeated three times. At each concentration, 10 experimental animals of 48 hours old Artemia salina Leach larvae were used. The toxic effect of the extract was identified by the percentage of mortality of Artemia salina Leach larvae using probit analysis (LC50). The results showed the linear regression equation y = 3.0809x – 12.065. This shows that the mortality of the test animals reached 50% when the compound concentration reached 34,599 ppm. Based on the toxicity test of the methanol extract of the tapak dara flower (Catharanthus roseus) using the Brine Shrimp Lethality Test (BSLT) method, in this study it was toxic because LC50>1000 ppm so it has potential as an anticancer.
Co-Authors Adek Chan Chemayanti Surbakti Dewi Kristiani Mendrofa Melia Sari Nita Andriani Lubis Tetty Noverita Khairani Willy Novita Sari