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All Journal Jurnal EduHealth COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Jurnal Sosial dan Sains
Hasna Nisrina
Universitas Singaperbangsa Karawang
Humanities Astronomy Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Library & Information Science Physics Public Health Social Sciences Veterinary

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Metode Validasi Golongan Obat Beta Blocker dalam Plasma Darah Manusia Menggunakan Metode HPLC Andien Ravelliani; Hasna Nisrina; Lala Komala Sari; Marisah Marisah; Riani Riani; Annastya Eka Agustin; Faizal Auladi Rivianto
COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat Vol. 2 No. 1 (2022): COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/comserva.v2i1.205

Abstract

Bisoprolol and atenolol are beta blockers that selectively act on 1 receptors in the heart. This drug is used for the treatment of hypertension. Hypertension is an event where there is an abnormal increase in blood pressure in the arteries on a continuous basis. The normal range for blood pressure is 120/80 mmHg. The writing of this review article reviews the effect of antihypertensive drug compounds in biological samples, namely on human blood plasma using HPLC methods. Based on the results of several journals that have been reviewed, it was concluded that the drug compounds bisoprolol and atenolol in human blood plasma obtained accurate results through these two instruments.
Description of Side Effects of Using Antituberculosis Drug in Pulmonary Tuberculosis Patients: Literature Review Hasna Nisrina; Indah Laily Hilmi
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (185.15 KB)

Abstract

Pulmonary tuberculosis (TB) is a chronic and infectious disease that is still a global concern. The bacterium that causes tuberculosis is the bacterium Mycobacterium tuberculosis. The high incidence of tuberculosis is due to the rapid spread of bacteria caused by the easy transmission of the disease, namely through the droplet nucleus containing Mycobacterium tuberculosis. Tuberculosis morbidity and mortality is a serious problems, especially due to the emergence of side effects of Anti Tuberculosis Drugs (OAT). most sufferers feel unable to tolerate the side effects of OAT experienced during the treatment process. This study aimed to determine the side effects felt by patients with pulmonary tuberculosis who used antituberculosis drugs. The most widely used method is the descriptive method with a cross-sectional approach with different data collection. The results showed that side complaints caused by OAT ranged from mild effects: nausea, abdominal pain, joint pain, tingling, and red urine to severe side effects, namely respiratory syndrome (shortness of breath), itching, and redness of the skin, deafness, jaundice. without other causes, visual disturbances, and vomiting.
Identifikasi dan Isolasi Senyawa Glikosida Saponin dari Beberapa Tanaman di Indonesia Andien Ravelliani; Hasna Nisrina; Lala Komala Sari; Marisah Marisah; Riani Riani
Jurnal sosial dan sains Vol. 1 No. 8 (2021): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5020.518 KB) | DOI: 10.59188/jurnalsosains.v1i8.176

Abstract

Glikosida merupakan salah satu senyawa metabolit sekunder yang terdiri atas gabungan dua bagian senyawa, yaitu glikon dan aglikon. Saponin merupakan glikosida bagian aglikon yang termasuk kedalam golongan glikosida triterpena dan sterol. Saponin memiliki banyak kegunaan untuk kesehatan diantaranya, sebagai immunomodulator, antivirus, antitumor, antiinflamasi, antijamur, dan efek hipokolesterol. Senyawa glikosida saponin tersebar luas pada beberapa tanaman di Indonesia. Penulisan review artikel ini mengulas tentang keberadaan senyawa glikosida saponin pada beberapa tanaman yaitu Daun Binahong (Anredera cordifolia (Ten.) Steenis), Pelepah Pisang Uli (Musa paradisiaca L.), Herba Pegagan (Centella asiatica L. Urban), Daun Majapahit (Cresentia cujete), dan Daun Bungkus (Smilax rotundifollia). Metode yang digunakan dalam identifikasi dan isolasi senyawa glikosida saponin mulai dari esktraksi maserasi, skiring fitokimia dengan cara uji saponin dan uji pewarna Liebermann Burchard (LB), fraksinasi secara ECC (Ekstraksi cair-cair), metode pemisahan Kromatografi Lapis Tipis (KLT), dan metode pemisahan lainnya. Berdasarkan hasil dari beberapa jurnal yang telah ditelaah, diperoleh kesimpulan bahwa lima tanaman tersebut positif mengandung senyawa glikosida saponin.
Co-Authors Andien Ravelliani Andien Ravelliani Annastya Eka Agustin Faizal Auladi Rivianto Indah Laily Hilmi Lala Komala Sari Marisah Marisah Riani Riani