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All Journal Jurnal EduHealth COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Jurnal Sosial dan Sains Jurnal Farmasetis
Marisah Marisah
Universitas Singaperbangsa Karawang
Humanities Astronomy Economics, Econometrics & Finance Education Environmental Science Health Professions Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Physics Public Health Social Sciences Veterinary

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Metode Validasi Golongan Obat Beta Blocker dalam Plasma Darah Manusia Menggunakan Metode HPLC Andien Ravelliani; Hasna Nisrina; Lala Komala Sari; Marisah Marisah; Riani Riani; Annastya Eka Agustin; Faizal Auladi Rivianto
COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat Vol. 2 No. 1 (2022): COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/comserva.v2i1.205

Abstract

Bisoprolol and atenolol are beta blockers that selectively act on 1 receptors in the heart. This drug is used for the treatment of hypertension. Hypertension is an event where there is an abnormal increase in blood pressure in the arteries on a continuous basis. The normal range for blood pressure is 120/80 mmHg. The writing of this review article reviews the effect of antihypertensive drug compounds in biological samples, namely on human blood plasma using HPLC methods. Based on the results of several journals that have been reviewed, it was concluded that the drug compounds bisoprolol and atenolol in human blood plasma obtained accurate results through these two instruments.
Study Of Molecular Docking On Compounds With Potential As Anti-Inflammatory Andien Ravelliani; Hasna' Nisrina; Lala Komala Sari; Marisah Marisah; Annastya Eka Agustin; Dhavina Maharani; Marsah Rahmawati Utami; Lina Nurfadhila
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (232.665 KB)

Abstract

Inflammation is a protective response caused by damage to certain tissues. Anti-inflammatory is a substance or drug used to treat redness, increased body temperature, swelling, pain and loss of function of an organ. Steroid and non-steroidal anti-inflammatory drugs have many side effects, so studies are needed to develop new drugs to minimize side effects and improve therapeutic effects. The method used is literature review from journals and articles obtained from Google Scholar in 15 journals. The purpose of the literature review is to find out the study of the development of new drugs from several compounds that have potential as anti-inflammatories. Secondary metabolites that have potential as anti-inflammatory include essential oils, flavonoids, alkaloids, terpenoids, and anthocyanins. Secondary metabolites will interact with the cyclooxygenase (COX) enzyme which is the main mediator of inflammation. The results obtained from the 15 compounds contain these secondary metabolites so they have the potential as anti-inflammatory.
Literature Review: Content Analysis And Synthesis Of Natural Dyes In Food And Beverages Circulating In The Community Andien Ravelliani; Lala Komala Sari; Hermin Marlian; Marisah Marisah; Marsah Rahmawati Utami; Lina Nurfadhila
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.81 KB)

Abstract

Food additives are ingredients added to food to improve color, shape, taste and texture, as well as to extend the shelf life, and are not the main ingredient. Colorants are often used to increase the attractiveness of food and drinks. There are generally two types of dyes, namely natural dyes and synthetic dyes. The method used in this literature review is derived from 16 journals from reliable sources. The results show of the 16 food and beverage samples used, there were 3 negative results of food and beverage ingredients that were prohibited from being used in food products and 13 of them were positive for containing prohibited food ingredients and exceeding the maximum dose permitted in accordance with existing regulations.  
Identifikasi dan Isolasi Senyawa Glikosida Saponin dari Beberapa Tanaman di Indonesia Andien Ravelliani; Hasna Nisrina; Lala Komala Sari; Marisah Marisah; Riani Riani
Jurnal Sosial dan Sains Vol. 1 No. 8 (2021): Jurnal Sosial dan Sains
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (5020.518 KB) | DOI: 10.59188/jurnalsosains.v1i8.176

Abstract

Glikosida merupakan salah satu senyawa metabolit sekunder yang terdiri atas gabungan dua bagian senyawa, yaitu glikon dan aglikon. Saponin merupakan glikosida bagian aglikon yang termasuk kedalam golongan glikosida triterpena dan sterol. Saponin memiliki banyak kegunaan untuk kesehatan diantaranya, sebagai immunomodulator, antivirus, antitumor, antiinflamasi, antijamur, dan efek hipokolesterol. Senyawa glikosida saponin tersebar luas pada beberapa tanaman di Indonesia. Penulisan review artikel ini mengulas tentang keberadaan senyawa glikosida saponin pada beberapa tanaman yaitu Daun Binahong (Anredera cordifolia (Ten.) Steenis), Pelepah Pisang Uli (Musa paradisiaca L.), Herba Pegagan (Centella asiatica L. Urban), Daun Majapahit (Cresentia cujete), dan Daun Bungkus (Smilax rotundifollia). Metode yang digunakan dalam identifikasi dan isolasi senyawa glikosida saponin mulai dari esktraksi maserasi, skiring fitokimia dengan cara uji saponin dan uji pewarna Liebermann Burchard (LB), fraksinasi secara ECC (Ekstraksi cair-cair), metode pemisahan Kromatografi Lapis Tipis (KLT), dan metode pemisahan lainnya. Berdasarkan hasil dari beberapa jurnal yang telah ditelaah, diperoleh kesimpulan bahwa lima tanaman tersebut positif mengandung senyawa glikosida saponin.
Studi dan Tatalaksana Terkait Penyakit Cacar Monyet (Monkeypox) yang Menginfeksi Manusia Marisah Marisah; Indah Laily Hilmi; Salman Salman
Jurnal Farmasetis Vol 11 No 3 (2022): Jurnal Farmasetis: November 2022
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (136.967 KB)

Abstract

Cacar Monyet disebabkan karena virus monkeypox (Orthopoxvirus, Family Poxviridae) ditemukan pada tahun 1958 di Denmark. Di Indonesia, kasus monkeypox pertama telah diketahui bahwa satu warga Indonesia terkonfirmasi positif cacar monyet (monkeypox). Metode yang digunakan adalah metode komparatif, literature review dikumpulkan dari 11 sumber dengan kata kunci “Cacar Monyet” dan “monkeypox”. Gejala awalnya yaitu demam, sakit kepala, dan nyeri punggung serta otot, lemas, ruam. Saat ini, belum adanya pengobatan yang tepat dalam kasus ini, namun masih mampu diatasi. Maka, perlu adanya studi dan tatalaksana seperti informasi lebih lanjut terkait penyakit cacar monyet, artikel ini bertujuan untuk memaparkan studi dan informasi agar masyarakat lebih mudah memahami. Adapun data dan sumber tinjauan ini terbukti bahwa informasi yang berkaitan dengan cacar monyet (monkeypox) sangat terbatas.
Isolasi Senyawa Limonen pada Minyak Atsiri Menggunakan Metode Uji Hidrodestilasi, Destilasi Uap dan Destilasi Air-Uap Vriezka Mierza; Andien Ravelliani; Bismar Al Bara; Marisah Marisah; Nur Sa’diyyah
Jurnal Farmasetis Vol 12 No 1 (2023): Jurnal Farmasetis: Februari 2023
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (201.792 KB)

Abstract

Minyak atsiri merupakan suatu senyawa yang mudah menguap dan memiliki kelarutan yang rendah terhadap air, dapat diperoleh dari hasil ekstraksi daun, buah, kulit buah, kayu, bunga dan biji-bijian. Pada minyak atsiri terdapat salah satu senyawa monoterpen limonen yang biasanya dimanfaatkan sebagai bahan aditif makanan, kosmetik, perasa hingga aroma tambahan. Metode review article dilakukan melalui penelusuran di Google cendekia dengan mensortir 15 artikel terkait dan dipilih 5 artikel yang dianggap sesuai dengan topik yang diinginkan. Hasil isolat yang diperoleh kemudian dianalisis menggunakan GC-MS (Gas Cromatography and Mass Spectroscopy) untuk mengetahui jenis senyawa kimia yang terkandung beserta kadarnya.
Co-Authors Andien Ravelliani Andien Ravelliani Annastya Eka Agustin Bismar Al Bara Dhavina Maharani Faizal Auladi Rivianto Hasna Nisrina Hasna' Nisrina Hermin Marlian Indah Laily Hilmi Lala Komala Sari Lina Nurfadhila Marsah Rahmawati Utami Nur Sa’diyyah Riani Riani Salman Salman Vriezka Mierza