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All Journal Jurnal Farmasi Indonesia Jurnal Ilmiah Cendekia Eksakta Jurnal Insan Farmasi Indonesia Jurnal Komunitas Farmasi Nasional
Weni Puspita
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Physics Public Health

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Journal : Jurnal Farmasi Indonesia

 1 
Formulasi Hair Tonic dari Ekstrak Etanol, Fraksi Etanol, dan Fraksi Kloroform-Metanol Kayu Secang (Caesalpinia sappan L.) Dina Yuspita Sari; Ratna Widyasari; Weni Puspita
Jurnal Farmasi Indonesia Vol 18 No 2 (2021): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31001/jfi.v18i2.954

Abstract

Secang wood (Caesalpinia sappan L.) has been used as an antioxidant in cosmetic products. The bioactive compound contained in secang wood are brazilin, brazilein, 3ยด-O-methylbrazilin, sappanone, chalcone, and sappankalkon as secondary metabolite components. This study aims to formulating hair tonic from extracts and fractions of secang wood and to determine the quality of hair tonic formulas using ethanol extract (Eet), ethanol fraction (Fen), and chloroform-methanol fraction (Fkm) of secang wood. The extraction process was carried out using maceration with 96% ethanol as ellent, after that extact partitioned using n-hexane. Fen was then applied using vacuum column chromatography using chloroform, chloroform: methanol (5:1), and methanol as eluent. Eet, Fen, and Fkm of secang wood were then formulated. Hair tonic evaluation includes organoleptic test, determination of pH value, viscosity determination, homogeneity test, and hair growth activity. The results showed that the three hair tonic formulas produced red-orange color, smelled aromatic in solution form, had a pH of 7, were homogeneous, had a viscosity of 3 cps, and showed activity on hair growth and hair weight of rabbits. FIII gave significantly different results from negative control (p <0.05) on rabbit hair length data on day 30, so ii can be concluded that FIII shows the best activity. All three formulas were qualify according to standard requirements and has activity on hair growth.
Co-Authors Athiah Masykuroh Ayu Shabrina Dina Yuspitasari Ika Ristia Rahman Puspasari, Heny Ratna Widyasari Rika Fitria