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All Journal Jurnal Farmasi Udayana Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Komunitas Farmasi Nasional
Ika Ristia Rahman
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Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Physics Public Health

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UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN BUAS-BUAS (Premna serratifolia L.) ASAL KABUPATEN MELAWI PROVINSI KALIMANTAN BARAT DENGAN METODE DPPH Weni Puspita; Dina Yuspita Sari; Ika Ristia Rahman
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.532

Abstract

Buas Buas (Premna serratifolia L.) contains secondary metabolites of flavonoids, saponins, tannins and triterpenoids/steroids, where flavonoids are known to have antioxidant properties and counteract free radicals. Antioxidants are compounds that can fight toxic hazards and reduce cell damage to the body caused by free radical oxidation. The purpose of this study was to determine the antioxidant activity of ethanol extracts of buas-buas leaves was carried out by DPPH (2,2-diphenyl-1-picrylhydrazyl), using UV-Vis spectrophotometry at wavelength 518.40 nm with various concentrations of 10 ppm, 20 ppm, 30 ppm, 40 ppm and 50 ppm. The results showed that Buas Buas leaves (Premna serratifolia L.) had an antioxidant activity with IC50 values ??of 20.66 ug / mL.
Keamanan Hair Tonic Ekstrak Etanol, Fraksi Etanol, dan Fraksi Kloroform-Metanol dari Kayu Secang (Caesalpinia sappan L.) dengan Metode Uji Iritasi Primer dan HET-CAM Dina Yuspita Sari; Ika Ristia Rahman
Jurnal Farmasi Udayana Vol. 10, No 2, Tahun 2021
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2021.v10.i02.p08

Abstract

Hair tonic is a hair care cosmetic to reduce hair loss, stimulate, and increase hair volume. Secang wood (Caesalpinia sappan L.) has the potential to be developed as an active substance in hair tonic products because it contains flavonoids, polyphenols, including brazilin which are used to treat damage hair. To ensure the safety of hair tonic products, safety tests are required, including skin and eye irritation tests. This study aims to determine the safety of hair tonic formula of ethanol extract, ethanol fraction, and chloroform-methanol fraction from sappan wood. Ethanol extract, ethanol fraction, and chloroform-methanol fraction of sappan wood were formulated into hair tonic preparations. The hair tonic safety test includes: primary irritation test and eye irritation test using HET-CAM method. Based on the primary irritation test, the score of erythema and edema on the skin obtained a PII value of 0 (non-irritating category). The HET-CAM test on the three hair tonic formulas, positive control and negative control, showed that the positive control (lactic acid) resulted in an irritation score of 9.51 (strong irritation category); negative control (NaCl 0.9%) and the three hair tonic formulas had an irritation score of 0 (no irritation category). This indicates that the hair tonic formula from ethanol extract, ethanol fraction, and chloroform-methanol fraction of sappanwood is not irritating and safe to use. Keywords: HET-CAM, primary irritation test, sappan wood
POTENSI TABIR SURYA EKSTRAK ETANOL DAUN MATOA (POMETIA PINNATA) DENGAN VARIASI KONSENTRASI PELARUT Erwan Kurnianto; Ika Ristia Rahman
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 1 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (228.537 KB) | DOI: 10.36387/jiis.v7i1.835

Abstract

Secondary metabolite compounds that have potential as sunscreens are flavonoids with chromophore groups. Flavonoid compounds are found in the matoa plant (Pometia pinnata). This study aimed to determine the possibility of matoa extract sunscreen with various solvent concentrations. Variations in the concentration of ethanol used were 50%, 70% and 96% ethanol. Matoa leaf simplicia was macerated with each solvent for 3×24 hours. Then the macerate was concentrated using a rotary evaporator. The viscous extract was tested for flavonoid qualitative using the staining method and tested for sunscreen potency using UV-Vis spectrophotometry with absorbance readings at a 290-320 nm wavelength. The potential for sunscreen in the form of an spf value is calculated using the Mansur equation. The results showed that the ethanolic extract of matoa leaves contained flavonoid. Matoa leaf extract has sunscreen potential. The highest SPF value in the extract with 70% ethanol solvent provides ultra protection value.
Antioxidant Screening and Sunscreen Activity of Nanocream of Purified Extract of Kenikir Leaves (ETDK) and Tampoi Fruit Peel Extract (EKBT): Skrining Antioksidan dan Aktivitas Tabirsurya Nanokrim Ekstrak Terpurifikasi Daun Kenikir (ETDK) dan Ekstrak Kulit Buah Tampoi (EKBT) Ika Ristia Rahman; Dian Kartikasari; Erwan Kurnianto; Sulastri Herdaningsih
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 7 No. 3 (2021): (December 2021
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2021.v7.i3.15663

Abstract

Background: UV lights are free radicals that can cause damage to the skin, such as redness, burning, pigmentation, and even cancer. Kenikir leaf purified extract (ETDK) and Tampoi fruit peel extract (EKBT) contain flavonoid compounds. Flavonoid compounds can be antioxidants and sunscreens due to the presence of chromophore groups that can absorb UV rays to reduce exposure to the skin. Objectives: This study aims to determine the antioxidant activity and the ability of sunscreen nano cream Purified extract of Kenikir leaves and Tampoi fruit peel extract. Material and metode: Nanocream is made with 3 ETDTK-EKBT combination formulas, II ETDK formulas, III EKBT formulas. The antioxidant activity test was carried out using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method and the sunscreen activity test using the UV-Vis spectrophotometric method to calculate the SPF value of the preparation (Mansur's method). Result: The results showed that the nano cream formula had a strong antioxidant activity with the per cent inhibition of formula I 78.28%, formula II 68.49%, and formula III 73.00%. The activity test results as a sunscreen formulation of purified extract nano cream from Kenikir leaves and nano cream from Tampoi fruit peel extract had extra protection ability with a sun-protecting factor value of 7 while the nano cream formula combined extract with an SPF value of 10 gave the maximum protection category. Conclusion: nano cream have potential as antioxidants and sunscreens.
UJI SPF DAUN KESUM (Polygonum minus Huds) PADA BEBERAPA PELARUT MENGGUNAKAN SPEKTROFOTOMETRI UV-Vis Dian Kartikasari; Rifki Fahmi; Ika Ristia Rahman; Hairunnisa; Abduh Ridha
Jurnal Komunitas Farmasi Nasional Vol. 3 No. 1 (2023): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kesum leaves (polygonum minus huds) have many benefits. Kesum leaves contain useful compounds such as alkaloids, flavonoids, and phenolics which can protect against free radicals caused by UV rays and absorb UV rays. This study used the UV-Vis spectrophotometry method. Absorbance was measured at a wavelength of 290-320 nm. The determination of the SPF value is based on the Mansur equation. The test results showed that the ethanol extract of daun kesum (polygonum minus huds) had SPF activity on methanol extract (22.803), 50% ethanol extract (20.0606), 70% ethanol extract (24.36), and 96% ethanol extract (25). ,8416) all belong to the ultra protection class.
Co-Authors Abduh Ridha dian kartikasari Dian Kartikasari Dina Yuspitasari Erwan Kurnianto Erwan Kurnianto Hairunnisa Rifki Fahmi Sulastri Herdaningsih Weni Puspita