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All Journal Sari Pediatri Paediatrica Indonesiana Journal of Dedicators Community
Yetty Movieta Nency
Department Of Child Health, Diponegoro University Medical School/Dr. Kariadi Hospital
Arts Humanities Education Health Professions Medicine & Pharmacology Public Health Social Sciences

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Latar Belakang Penyakit pada Penggunaan Transfusi Komponen Darah pada Anak Yetty Movieta Nency; Dana Sumanti
Sari Pediatri Vol 13, No 3 (2011)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (46.004 KB) | DOI: 10.14238/sp13.3.2011.159-64

Abstract

Latar belakang.Aplikasi transfusi darah dalam klinis sehari-hari dapat sebagai terapi pengganti maupun suportif. Sesuai pertimbangan risiko dan manfaat tranfusi komponen darah seperti thrombocyt concentrate(TC) packed red cell(PRC), fresh frozen plasma(FFP), platelete rich plasma (PRP), dan cryoprecipitate/kriopresipitat lebih direkomendasikan daripada whole blood(WB). Tujuan.Mengetahui hubungan antara latar belakang penyakit dengan penggunaan transfusi komponen darah.Metode.Penelitian retrospekstif dilakukan di Ruang Anak Rumah Sakit Dr Kariadi Semarang. Data diperoleh dari register bank darah rumah sakit tahun 2008-2010. Latar belakang penyakit ditentukan dengan mengidentifikasi diagnosis pada setiap kasus transfusi. Komponen darah yang diteliti PRC, TC, FFP, PRP, dan kriopresipitat. Utilisasi dengan menghitung total jumlah komponen darah yang dipakai per diagnosis penyakit, dan rerata pemakaian produk darah per jumlah kasus terindikasi transfusi per tahun. Analisis uji statistik hubungan dengan menggunakan Chi square.Hasil.Terdapat peningkatan rerata utilisasi darah 5678 unit darah per tahun. Terdapat peningkatan penggunaan selama 3 tahun terakhir, secara berurutan adalah 3751, 6496, dan 6787 unit darah (p<0.001). Komponen darah yang paling banyak digunakan berturut-turut adalah TC 3228 unit, PRC 1682 unit, FFP 295 unit, PRP 224 unit, dan cryo133 unit. Pasien leukemia merupakan pengguna komponen darah terbanyak dengan rerata pemakaian per tahun 2098 unit, diikuti oleh sepsis 893 unit, dan thalassemia 568 unit. Rasio kebutuhan PRC terbanyak untuk kasus penyakit jantung (2,23) diikuti penyakit ginjal (2,25) dan thalassemia (1,7). Untuk penggunaan TC, terbanyak berturut-turut adalah ITP (14,70 unit), anemia aplastik (9,8 unit), dan leukemia (6 unit). Terdapat hubungan antara diagnosis penyakit dengan penggunaan transfusi komponen PRC, TC, dan plasma (p<0,001).Kesimpulan.Terdapat hubungan antara latar belakang penyakit penyebab dengan penggunaan transfusi komponen darah. Leukemia, sepsis, dan thalassemia adalah latar belakang penyakit yang paling banyak menggunakan transfusi komponen darah. Berturut turut komponen darah yang banyak digunakan adalah konsentrat trombosit, komponen sel darah merah, serta plasma darah segar.
Initial brain CT scan and shunting outcomes in children with hydrocephalus Andi Anita Utami; Alifiani Hikmah Putranti; Yetty Movieta Nency; Eddy Sudijanto
Paediatrica Indonesiana Vol 53 No 4 (2013): July 2013
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (120.484 KB) | DOI: 10.14238/pi53.4.2013.200-3

Abstract

Background Hydrocephalus is one of the most common clinicalconditions affecting the central nervous system, with a congenitalhydrocephalus incidence of 3-4 per 1000 births. Incidence ofacquired types of hydrocephalus is unknown. Brain computerisedtomography (CT) scan can be used to assess the size of ventriclesand other structures. Shunting has long been performed toalleviate hydrocephalus. Shunting has dramatically changed theoutlook of children with hydrocephalus, with many of them havingnormal life expectancies and attaining normal intelligence.Objective To determine the outcomes of shunting in childrenwith hydrocephalus based on initial brain CT scan.Methods We performed a cross-sectional study in Dr. KariadiHospital. Initial brain CT scan data were collected from themedical records of children admitted to the Neurosurgery Wardfor ventriculoperitoneal (VP) shunt surgery from January 2009to December 2010. We studied the brain CT scan findings beforeVP shunt surgery and the outcomes of the children after VP shuntsurgery. Radiological findings were determined by a radiologistresponsible at that time.Results This study consisted of 30 subjects, 19 boys and 11girls. Initial brain CT scans to assess disease severity revealed thefo llowing conditions: lateral ventricle dilatation in 7 subjects,lateral and third ventricle dilatation in 16 subjects, and lateral,third and fourth ventricle dilatation in 7 subjects. After VPshunt surgery, 3 subjects in the lateral, third and fourth ventricledilatation category died. They were grouped according to theircondition. Group 1 consisted of subjects with only lateral ventricledilatation and subjects with lateral and third ventricle dilatation(23 subjects), while group 2 consisted of subjects with lateral,third and fourth ventricle dilatation (7 subjects). More survivorswere found in group 1 than those in group 2.Conclusion Less severe initial brain CT scan findings areassociated with better shunting outcomes children withhydrocephalus.
Pemeriksaan Bone Mineral Density dan Pelatihan Senam Osteoporosis Sebagai Upaya Peningkatan Kewaspadaan Osteoporosis pada Penderita Talasemia Mayor Nyoman Suci Widyastiti; Edward Kurnia Setiawan Limijadi; Meita Hendrianingtyas; Ariosta Ariosta; Dwi Retnoningrum; Dwi Ngestiningsih; Yetty Movieta Nency
Journal of Dedicators Community Vol 5, No 2 (2021)
Publisher : Universitas Islam Nahdlatul Ulama Jepara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34001/jdc.v5i2.1348

Abstract

Thalassemia major patients with routine transfusions are at risk of experiencing iron overload and bone turn over disorders which will increase the risk of osteoporosis. Community training activities with BMD examinations and osteoporosis exercise training in thalassemia major patients are expected to identify the prevalence of bone fragility in thalassemia major patients, increase the awareness of thalassemia major patients and their families to the risk of osteoporosis in thalassemia major patients and osteoporosis exercise training as an effort to prevent osteroporosis. The results of BMD on the spine showed 57.1% osteoporosis, 28.6% normal and 14.3% osteopenia. The results of BMD examination on the cervical spine showed 71.4% osteopenia, 21.4% normal and 7.2% osteoporosis. The results of BMD examination on the femur found 50% normal, 42.8% osteopenia and 7.2% osteoporosis. The bone location with the highest percentage of osteoporosis was the spine (57%), and the bone location with the highest percentage of osteopenia was the neck bone (71.4%). The high percentage of osteopenia locations in the cervical spine of thalassemia major patients with repeated transfusions should be become a concern. Based on these findings, we held education and counselling on the risk of osteoporosis in thalassemia patients with repeated transfusions, osteoporosis exercise training and distribution of osteoporosis exercise compact disk (CD) for at home osteoporosis exercise training.
Co-Authors Alifiani Hikmah Putranti Andi Anita Utami Ariosta Ariosta Dana Sumanti Djuara P Lubis Dwi Retnoningrum Eddy Sudijanto Edward Kurnia Setiawan Limijadi Meita Hendrianingtyas Nyoman Suci Widyastiti