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All Journal Alotrop Jurnal Pendidikan dan Ilmu Kimia Jurnal Insan Farmasi Indonesia Proceeding of Mulawarman Pharmaceuticals Conferences Jurnal AFAMEDIS Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Panji Ratih Suci
Akademi Farmasi Mitra Sehat Mandiri Sidoarjo
Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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ANALISIS KADAR BETA KAROTEN DAN VITAMIN C BUAH JUWET (Syzigium cumini ) secara SPEKTROFOTOMETRI UV-VIS Panji Ratih Suci; Nadya Hapsari; Reny Dwi
Jurnal Insan Farmasi Indonesia Vol 4 No 1 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i1.601

Abstract

Beta-carotene (?-Carotene) is an organic compound and is classified as a terpenoid. ?-Carotene is a red-orange pigment that is very abundant in plants and fruits. Beta-carotene is thought to have many functions that other compounds do not have (Subawati, 2009). The aim of this study was to determine ?-carotene levels in juwet fruit (Syzygium Cumini) by UV-Vis spectrophotometry. Juwet fruit samples (Syzygium Cumini) were extracted with acetone as a solvent. The extract obtained was extracted again with petroleum ether solvent, then saponified with 15% KOH solvent in methanol. The extract was liberated with distilled water. The extract obtained was dried over anhydrous Na2SO4. The extract obtained was analyzed qualitatively using Thin Layer Chromatography, and UV-Vis spectrophotometry at a wavelength of 332.1539 nm. The average level of ?-carotene in juwet fruit was 1.25 mg. Analysis of Vitamin C levels was carried out at a wavelength of 265.3 nm, the average level of Vitamin C in juwet fruit was 1.473
Formulasi dan Uji Mutu Fisik Ekstrak Daun Binahong (Anredera cordifolia (Ten.) Steenis) sebagai Sabun Cair: Formulation and Physical Quality of Binahong Leaves Extract (Anredera cordifolia (Ten.) Steenis) as Liquid Soap Chyntia Maharani; Panji Ratih Suci; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.908 KB) | DOI: 10.25026/mpc.v13i1.443

Abstract

Acne or Acne vulgaris is a problem that is often experienced at all ages, especially in adolescents. One of the causes of acne is that the polysebase ducts (oil glands in the skin and hair) become blocked and cause the production of skin oil (sebum) which becomes food for bacteria. The flavonoids contained in the leaves of Binahong (Anredera cordifolia (Ten.) Steenis) can inhibit bacterial growth. This study aims to formulate the Binahong leaf extract (Anredera cordifolia (Ten.) Steenis) into liquid soap preparation and evaluate the physical quality of the preparation. The extraction method used in this study was maceration using 96% ethanol as a solvent. Liquid soap Binahong Leaf extract (Anredera cordifolia (Ten.) Steenis) is made into four formulas, namely F0 (containing 0% binahong leaf extract), F1 (containing 2% binahong leaf extract), F2 (containing 4% binahong leaf extract), and F3 (contains 6% binahong leaf extract). The physical quality test for liquid soap preparations includes organoleptic tests, homogeneity, pH, high foam, and dispersibility. The test results of the four liquid soap formulations showed that the four formulas did not experience organoleptic changes, were homogeneous, and met the pH requirements of 9.5-11. The pH range of liquid soap that meets the SNI requirements (06-3734-2006) is 8-11, the foam height range is 25-60 mm, and the spreadability range is 3-5 cm.
Formulasi dan Uji Mutu Fisik Sediaan Sabun Cair Herbal Ekstrak Daun Kemangi (Ocimum sanctum L.): Formulation and Physical Quality Test of Basil Leaf Extract Herbal Liquid Soap (Ocimum sanctum L.) Sukma Dewi Ayu Anggraini; Panji Ratih Suci; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (220.781 KB) | DOI: 10.25026/mpc.v13i1.465

Abstract

Acne is a skin problem that is often a problem for most teenagers in Indonesia. This acne can occur due to a lack of facial hygiene, which causes the growth of bacteria. Basil (Ocimum sanctum L.) is a plant that grows in Indonesia and contains alkaloids, saponins, flavonoids and tannins which can inhibit the growth of bacteria. The purpose of this study was to utilize Basil extract (Ocimum sanctum L.) into liquid soap preparation and evaluate the physical quality of the preparation. Basil extract (Ocimum sanctum L.) can be obtained by using the maceration method using 96% ethanol as a solvent. Liquid soap preparation formulations are made with extract concentrations of 2%, 4%, and 6% with a uniform liquid soap base. Evaluation of liquid soap preparations includes tests for homogeneity, organoleptic, pH, dispersibility, and high foam. The results of the three liquid soap formulations showed that the three formulations were homogeneous and there was no organoleptic change, the pH range of liquid soap 9-11 which fulfilled the pH requirements of liquid soap according to SNI No. 06-4085-1996, namely 8 - 11, the spreadability test range is 2.7 - 3cm and the foam height test range is 3 ? 8,5cm.
AKTIVITAS ANTIOKSIDAN DAN SKRINNING FITOKIMIA EKSTRAK ETANOL DAUN SINTRONG (Crassocephalum crepidioides (Benth) S. Moore) indah trilestari; Panji Ratih Suci; Erna Fitriany
AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Antioxidants is an important role in the body's defense against disease, because antioxidant compounds are able to prevent the bad influence caused by free radicals. Sintrong leaves (Crassocephalum crepidioides (Benth) S. Moore) has a compound of saponins, tannins, alkaloids and flavonoids known to be used as antioxidants. The purpose of the study to determine the activity of antioxidant and IC50 values as well as compounds contained there in and compared with Vitamin C as a positive control of antioxidant activity of sintrong leaves (Crassocephalum crepidioides (Benth) S. Moore). The research method uses DPPH attenuation method and then calculated by spectrophotometry to determine the antioxidant content. The results showed that ethanol extract of sintrong leaves has antioxidant activity that can ward off free radicals with IC50 value of 52.49 mg / ml. Conclusion there is antioxidant activity in sintrong leaf extract (Crassocephalum crepidioides (Benth) S. Moore) with IC50 value of 52.49 mg / ml (strong) but the antioxidant activity obtained greater positive control than the extract. This data is supported by the Independent T-Test the value of the thitung > ttabel, which means that there are differences in the antiokxidant activity of sintrong leaves and vitamin C. Keywords: Sintrong leaf, Free Radicals, Antioxidants, IC50.
Eco-friendly silver nanoparticles (AgNPs) fabricated by green synthesis using Capsicum annum L. extract: biosynthesis, characterization, and antibacterial activity Erna Fitriany Fitriany; Andri Priyoherianto; Panji Ratih Suci
ALOTROP Vol. 7 No. 1 (2023): Alotrop 2023
Publisher : University of Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/alo.v7i1.26546

Abstract

Silver nanoparticles (AgNPs) have many benefits in the health sector, it has antimicrobial and biomedical Activity. AgNPs can be synthesized by using green chemistry or using chemical substances, such as NaBH4. Green synthesis of AgNPs is an environmentally friendly alternative and has cost-effective production. Capsicum annuum L. combined with Saffron extract was used to synthesize AgNPs. The biosynthesis, characterization, and antibacterial activity of AgNPs were studied in this research. The synthesized AgNPs were characterized by UV- Visible spectroscopy (UV-Vis), Fourier- transform Infrared Spectroscopy (FTIR), and Particle Size Analyzer (PSA). The formation of AgNPs was confirmed by optical performance using UV-VIS spectroscopy and showing a peak of AgNPs at 407 nm. Capsicum Annuum L. combined with Saffron extract contained C-H, C-N, and C=O groups. The particle size was characterized using PSA, the size is 37,74 nm. Capsicum Annuum L. combined with Saffron extract has good antibacterial activity.  Keywords: Green Synthesis, AgNPs, Capsicum annuum L, Saffron.
Uji Aktivitas Antidiabetes Ekstrak Kulit Melinjo (Gnetum Gnemon L.) pada Mencit (Mus musculus) Ida Kristianingsih; Panji Ratih Suci; Zuanta Pangestuti
Jurnal Farmasi Indonesia AFAMEDIS Vol. 4 No. 2 (2023): AFAMEDIS || JURNAL FARMASI INDONESIA
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Diabetes is one of a number of diseases that result in too much sugar levels in the blood (high blood glucose), treatment with the example of the drug Glibenclamide can reduce blood sugar levels gradually, so alternative treatment is needed from natural ingredients. One of the natural ingredients that contain chemical compounds Flavonoids, Coumarins, and Triterpenoids, which have activity lowering blood sugar levels. The purpose of this study was to determine the activity of melinjo peel extract against antidiabetes in mice to determine the most effective dose of lowering blood sugar levels in male mice, in this study using this research method using melinjo peel extract (Gnetum gnemon L) with a dose of 200mg/kgBB ,250mg/kgBW and a dose of 42mg/kgBW which aims to determine the effect of melinjo peel extract as a decrease in blood sugar levels in male mice, shows that melinjo peel extract (Gnetum gnemon L.) is the most effective in reducing sugar levels at a dose of 42mg/kgBW, compared with positive control and doses of 28mg/kgBW and 35mg/kgBW. The results of the study concluded that melinjo peel extract (Gnetum gnemon L) in the 28mg/kgBW, 35mg/kgBW and 42mg/kgBW dose groups were the most effective in reducing blood sugar levels. 42 mg/kg body weight. The conclusion is that there is antidiabetic activity in the extra skin of melinjo (Gnetum gnemon L.) both at doses of 28mg/kgBW, 35mg/kgBW and 42mg/kgBW but the most effective for reducing blood sugar levels is at a dose of 42mg/kgBW compared to the positive control. This data is supported by repeated ANOVA test with a significant value of p=0.012 (p>0.05), which means that all groups have significant differences in both the extract and the comparison group used.
Analisis Kadar Logam Berat Timbal (PB) pada Makanan Kaleng Daging Giling Berbagai Merk Panji Ratih Suci; Muh. Latif 'Alim; Sulfika Oriza Nova Sativa
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.276

Abstract

Along with increasingly rapid technological developments in our country, the number of existing industries is increasing. Apart from producing useful products, this industry also produces waste. The waste produced contains a lot of heavy metals, one of which is the heavy metal lead. If the lead metal in the waste receives little treatment, this can cause pollution in the environment, even though this waste is present in small quantities, the lead condition is unstable and if it accumulates in the body, it can ultimately trigger cancer cells (carcinogenic) which can be dangerous for health. . In this research, adsorption of PB2+ ions was carried out on canned ground meat, where heavy metal contamination occurred in the ground meat. This research aims to determine the effectiveness of the absorption of heavy metals (Pb) contained in ground beef and their characteristics. The uptake of PB2+ ions in ground beef, measuring the concentration of PB2+ ions before and after receiving treatment, was carried out using an instrument, namely AAS, at a wavelength of 217nm. The research results showed that the effectiveness of ground beef in absorbing PB2+ ions in canned food was as high as brand a: 0.023; brand b: 0.009; brand c: 0.006
Co-Authors Andri Priyoherianto Chyntia Maharani cikra ikhda Nur Hamidah safitri ERNA FITRIANY, ERNA Ida Kristianingsih indah trilestari Muh. Latif 'Alim Nadya Hapsari Reny Dwi Sukma Dewi Ayu Anggraini Sulfika Oriza Nova Sativa Zuanta Pangestuti