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FORMULASI DAN UJI MUTU FISIK SEDIAAN LOTION EKSTRAK KULIT BUAH JAGUNG ( Zea mays L.) cikra ikhda Nur Hamidah safitri; Luluk Jubaidah
Jurnal Insan Farmasi Indonesia Vol 2 No 2 (2019)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v2i2.394

Corn plant is a plant that is widely cultivated in Indonesia. Utilization of corn husk waste so far has only been used as animal feed. Chemical content contained in corn, among others, flavonoids, alkaloids, phenols, steroids, tannins, maysin. This study aims to produce a lotion of corn husk extract and test the physical quality of the lotion preparation. This research consisted of extraction using maceration method with 70% ethanol. Lotion formulation with extract concentrations of 10%, 20% and 30%. Evaluation of the physical quality of the preparations included organoleptic, homogeneity, pH, dispersibility and storage stability tests for 30 days. The results showed that Corn skin extract lotion has a pH of 6, thick form, fine texture, fragrant aroma, light brown color (10%), dark brown (20% and 30%).Texture is homogeneous. The spread of pH test in concentrations of 10%, 20% and 30%, ie 6.3 cm, 6.5 cm, 6.5 cm. The physical quality stability of the lotion stable at room (25Â°C-30Â°C) and cold temperature (2Â°C-8Â°C). The conclusion of this study is that there is no difference in the three lotions concentrations of 10%, 20% and 30% which are stored at room temperature and cold temperature. Keywords: Corn rind extract, physical quality, lotion

PEGARUH VARIASI KONSETRASI BAHAN PENGIKAT PVP (Polyvinyl Pyrrolidone) TERHADAP MUTU FISIK TABLET KUNYIT (Curcuma domestica Val.) cikra ikhda safitri; Yeyen Dwi Aprilia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 4 No 2 (2020)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Diabetes Melitus (DM) adalah suatu penyakit kronis dan Indonesia merupakan peringkat ke-6 di dunia. Kunyit (Curcuma domestica Val.) mengandung 75% curcumin yang memiliki aktivitas sebagai antidiabetes. Penelitian ini bertujuan untuk memformulasikan tablet kunyit menggunakan metode granulasi basah dengan varian konsentrasi bahan pengikat 2,5% (F1) dan 5% (F2). Penelitian ini terdiri dari pembuatan simplisia, pembuatan ekstrak, pembuatan granul dengan variasi konsentrasi bahan pengikat 2,5% dan 5%, pencetakan tablet dengan cetak tablet single punch serta uji mutu fisik tablet. Tablet yang dihasilkan dilakukan pegujian mutu fisik yang meliputi uji keseragaman bobot, uji keseragaman ukuran, uji kekerasan tablet, uji waktu hancur tablet dan uji kerapuhan tablet. Analisis hasil menggunakan bantuan software SPSS dengan uji statistik non-parametric 2-independent sample atau mann whiteney U. Hasil uji mutu fisik tablet yang meliputi uji keseragaman bobot dengan hasil rata-rata F1 dan F2 adalah 320,75Â±3,56 dan 307,80Â±0,98. Uji keseragaman ukuran dengan rata-rata diameter F1 dan F2 adalah 1,00Â±0,00 dan 1,10Â±0,00, sedangkan rata-rata tebal F1 dan F2 adalah 0,31Â±0,00 dan 0,28Â±0,00. Uji kekerasan tablet dengan hasil rata-rata F1 dan F2 adalah 1,00Â±0,00. Uji waktu hancur tablet dengan hasil rata-rata F1 dan F2 adalah 840 detik dan 816 detik dan uji kerapuhan tablet dengan hasil rata-rata F1 dan F2 adalah 0,10Â±0,02 dan 0,26Â±0,00. Hasil uji statistik menunjukkan bahwa ada perbedaan yang signifikan diakibatkan karena adanya pengaruh dari perbedaan variasi konsentrasi bahan pengikat pada mutu fisik tablet berupa keseragaman bobot tablet dan waktu hancur tablet (sig <0,05).Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Kata kunci : Kunyit, diabetes melitus, tablet, Polyvinyl pyrrolidone (PVP)

Formulasi dan Uji Mutu Fisik Sediaan Sabun Padat Ekstrak Kulit Bawang Merah (Allium cepa L): Formulation and Physical Quality Test for Onion Skin Extract Solid Soap (Allium cepa L) Adelya Youan Nurdiana; Elly Purwati; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Shallots are one of the many types of plants available in Indonesia. Shallots are annual plants that can grow in the highlands and lowlands. In its use, shallots produce a lot of waste in the form of skin which can be processed into solid soap preparations because they contain antibacterial properties derived from flavonoid compounds. This study aims to produce solid soap onion skin extract and test the physical quality of the preparation according to the Indonesian National Standard (SNI). The research method was experimental which consisted of making simplicia and extracting it by maceration method using 70% ethanol as a solvent. Red onion peel extract formulations were used with a concentration of 5% (Formulation 2) and 0% (formulation 1) as the control basis. Evaluation of solid soap preparations includes organoleptic observation, homogeneity testing, foaming test, pH testing. The preparation was evaluated for 4 weeks at room temperature. Data were analyzed descriptively and compared with SNI. The results of this study indicate that the soap preparation is homogeneous, has a solid texture, is light brown (formulation 1), and dark brown (formulation 2). The average pH value in formulation 1 and formulation 2 is 9. The results of the organoleptic test on solid soap preparations did not change, from the first week to the fourth week it was getting denser. The foam power test on both formulations showed the presence of foam that came out when the test was carried out. The conclusion in this study is that the physical quality of onion skin extract solid soap is in accordance with SNI and is stable for 4 weeks of storage.

Formulasi dan Uji Mutu Fisik Sediaan Sabun Padat Ekstrak Daun Kelor (Moringa oleifera L.) : Formulation of Physical Quality Test For Moringa Leaf Extract Solid Soap (Moringa oleifera L.) Angelica Olsa Okta Rizky; Elly Purwati; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

The leaves of Moringa (Moringa oleifera L.) have the potential as a medicinal plant which can often be used as an alternative for the treatment of various diseases. Besides being able to be processed for food ingredients, Moringa leaves can also be used as an anti-cancer treatment, prevent anemia and can also inhibit the activity of bacteria and fungi. This study aims to produce solid soap for Moringa leaf extract and to test the physical quality according to the Indonesian National Standard (SNI). This research method is experimental which consists of the manufacture of simplicia and extraction using the maceration method with 70% ethanol solvent. formulation using Moringa leaf extract with a concentration of 0% (base), 3% (F1), and 5% (F2). Evaluation of the physical characteristics of solid soap includes organoleptic observation, homogeneity testing, pH test, foam power test. The preparation was evaluated for 4 weeks, the data were analyzed descriptively. The results of this study indicate that a solid soap preparation that is homogeneous, has a dense and smooth texture, has a fragrant aroma, base (white color), F1 (blackish green color), F2 (blackish green color). The average pH value on the basis, F1, F2 is 9.The organoleptic test results on base solid soap preparations, F1, F2 did not change from week 1 to 4. Base solid soap foam power test values, F1, F2 remain stable. The conclusion of this research is that the physical quality of the Moringa leaf extract solid soap meets the SNI requirements.

Formulasi dan Uji Mutu Fisik Ekstrak Daun Binahong (Anredera cordifolia (Ten.) Steenis) sebagai Sabun Cair: Formulation and Physical Quality of Binahong Leaves Extract (Anredera cordifolia (Ten.) Steenis) as Liquid Soap Chyntia Maharani; Panji Ratih Suci; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Acne or Acne vulgaris is a problem that is often experienced at all ages, especially in adolescents. One of the causes of acne is that the polysebase ducts (oil glands in the skin and hair) become blocked and cause the production of skin oil (sebum) which becomes food for bacteria. The flavonoids contained in the leaves of Binahong (Anredera cordifolia (Ten.) Steenis) can inhibit bacterial growth. This study aims to formulate the Binahong leaf extract (Anredera cordifolia (Ten.) Steenis) into liquid soap preparation and evaluate the physical quality of the preparation. The extraction method used in this study was maceration using 96% ethanol as a solvent. Liquid soap Binahong Leaf extract (Anredera cordifolia (Ten.) Steenis) is made into four formulas, namely F0 (containing 0% binahong leaf extract), F1 (containing 2% binahong leaf extract), F2 (containing 4% binahong leaf extract), and F3 (contains 6% binahong leaf extract). The physical quality test for liquid soap preparations includes organoleptic tests, homogeneity, pH, high foam, and dispersibility. The test results of the four liquid soap formulations showed that the four formulas did not experience organoleptic changes, were homogeneous, and met the pH requirements of 9.5-11. The pH range of liquid soap that meets the SNI requirements (06-3734-2006) is 8-11, the foam height range is 25-60 mm, and the spreadability range is 3-5 cm.

Formulasi dan Uji Mutu Fisik Sabun Herbal Padat Ekstrak Kulit Batang Kayu Manis (Cinnamomum burmanni): Formulation and Physical Quality Test of Solid Herbal Soap Cinnamon (Cinnamomum burmanni) Bark Extract Dewinta Hesti Dwi Nurani; Elly Purwati; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Researchers have conducted research on the 1% 3% concentration of cinnamon bark extract (Cinnamomum burmanii.) For the manufacture of herbal solid soap preparations and tested the physical quality of herbal solid soap preparations. Cinnamon has antibacterial properties. This study aims to determine the extract of cinnamon bark (Cinnamomum burmanii.) Can be used as solid soap with a concentration of 1%, 3% which meets the requirements of the physical quality test which includes pH test, foam power test, organoleptic test, and homogeneity test. The design of this research is experimental research and the data were analyzed descriptively. Cinnamon bark extract was obtained from the maceration process with 70% ethanol. Making herbal solid soap formulations and soap making using the Cold Process method. The treatment in this study the concentration method added was 1% 3%. The homogeneity test showed that the three solid soap formulations of cinnamon bark extract (Cinnamomum burmanii) remained homogeneous as indicated by the absence of coarse grains or particles on the surface of the herbal solid soap for cinnamon bark extract (Cinnamomum burmanii.) High stability of the foam with a height of 9cm and a pH value. already in accordance with SNI 06 - 3532 - 2016 with a pH value of 9-11 the organoleptic test shows different results.

Formulasi dan Uji Mutu Fisik Sediaan Sabun Padat Ekstrak Biji Alpukat (Persea americana): Formulation and Physical Quality Test of Solid Soap Extract of Avocado Seeds Sintya Zagita; Elly Purwati; Cikra Ikhda Nur Hamidah Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Research on avocado seed extract (Persea americana.) At 1% and 3% concentrations for the manufacture of solid soap preparations and physical quality testing of solid soap preparations has been carried out. Avocado seeds have the ability as an antioxidant which can inhibit the main factor in the aging process. This study aims to determine that avocado seed extract (Persea americana.) Can be used as a solid soap with a concentration of 1% and 3% which meet the physical quality test requirements which include pH test, foam power test, organoleptic test, and homogeneity test. The design of this research is experimental research. Avocado seed extract was obtained from the maceration process with 70% ethanol and phytochemical screening was carried out. Making soap formulation is done by calculating using the Lye Calculator and making soap using the Cold Process method. The research results were processed using descriptive analysis. The treatments in this research were the concentration methods added were 1% and 3%. The homogeneity test showed that the three solid soap formulations of avocado seed extract (Persea americana.) Were still homogeneous as indicated by the absence of coarse grains or particles on the surface of the avocado seed extract (Persea americana.) Solid soap which was seen in plain view on the solid soap without the addition of the extract and the concentration of 3%. Meanwhile, the concentration of 1% looks like it is semi-homogeneous. The organoleptic results showed different forms, the formula without the addition of extract and a concentration of 1% had a solid form while the formula with a concentration of 3% had a solid and hard form. The formula without the addition of the extract and the concentration of 1% has a distinctive aroma of lux soap while the formula with a concentration of 3% has a distinctive aroma of avocado seed leaves which is more concentrated, the color of the preparation in each formula is different, influenced by variations in the concentration of mango leaf extract. The high stability of the foam with a height of 9cm and a pH value is in accordance with SNI 06 - 3532 - 2016 with a pH value of 9-11.

Formulasi dan Uji Mutu Fisik Sediaan Sabun Cair Herbal Ekstrak Daun Kemangi (Ocimum sanctum L.): Formulation and Physical Quality Test of Basil Leaf Extract Herbal Liquid Soap (Ocimum sanctum L.) Sukma Dewi Ayu Anggraini; Panji Ratih Suci; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Acne is a skin problem that is often a problem for most teenagers in Indonesia. This acne can occur due to a lack of facial hygiene, which causes the growth of bacteria. Basil (Ocimum sanctum L.) is a plant that grows in Indonesia and contains alkaloids, saponins, flavonoids and tannins which can inhibit the growth of bacteria. The purpose of this study was to utilize Basil extract (Ocimum sanctum L.) into liquid soap preparation and evaluate the physical quality of the preparation. Basil extract (Ocimum sanctum L.) can be obtained by using the maceration method using 96% ethanol as a solvent. Liquid soap preparation formulations are made with extract concentrations of 2%, 4%, and 6% with a uniform liquid soap base. Evaluation of liquid soap preparations includes tests for homogeneity, organoleptic, pH, dispersibility, and high foam. The results of the three liquid soap formulations showed that the three formulations were homogeneous and there was no organoleptic change, the pH range of liquid soap 9-11 which fulfilled the pH requirements of liquid soap according to SNI No. 06-4085-1996, namely 8 - 11, the spreadability test range is 2.7 - 3cm and the foam height test range is 3 ? 8,5cm.

Formulasi dan Uji Mutu Fisik Sediaan Body Scrub dari Arang Aktif Sekam Padi (Oryza sativa): Formulation and Physical Quality Test of Provision of Body Scrub from Rice Husb Active Character (Oryza sativa) Chelsie Onesya Prolapita; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Rice husk (Oryza sativa) has a high content of activated carbon, activated charcoal is able to open clogged pores and improve skin cleansing by removing dead skin on the surface. Activated charcoal rice husk formulated sebagai scrubs using stearic acid, cethyl alcohol, and propilenglikol. Scrub as a scrub to remove dead skin cells using amylum oryzae. The concentration of activated rice husk charcoal used was 0% in the control formula, 8 % in formula I, 10% in formula II, and 12% in formula III. Evaluation Physical quality of body scrub based on parameters such as organoleptic, homogeneity test, pH test, spreadability test, adhesion test, emulsion type test. Body scrubs activated charcoal rice husk has a stable pH 7. Dispersibility formulation is 5,7cm, 5,8cm, 5,6cm. Rice husk activated charcoal body scrub is stable in room temperature storage or low temperature (2-8?C). All formulations evenly distributed homogeneously have stable color, smell and taste. Rice husk activated charcoal (Oryza sativa) can be formulated into a stable body scrub that meets the requirements. The most stable formulation was formulation 1 with a concentration of rice husk activated charcoal (Oryza sativa) of 8%.

Formulasi dan Uji Mutu Fisik Sediaan Pasta Gigi Herbal Ekstrak Temu Putih (Curcuma zedoaria): Formulation and Physical Quality of Temu Putih Extract (Curcuma zedoaria) as Herbal Toothpaste Deva Rahayu Nurindah Kusuma Wardani; Cikra Ikhda Nur Hamida Safitri
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Dental caries is one of the oral and dental problems in Indonesia. One of the causes of dental caries is the accumulation of dental plaque which is caused by food scraps that stick to the teeth and undergo fermentation by bacteria. Temu Putih (Curcuma zedoaria) is a native Indonesian plant that contains flavonoids, tannins and saponins that can inhibit bacterial growth. The purpose of this study was to formulate the extract of temu putih (Curcuma zedoaria) into toothpaste and evaluate the physical quality of these preparations. The temu putih extract was obtained by maceration method using 96% ethanol as a solvent. The toothpaste preparation formulation was made with a concentration of extract of temu putih (Curcuma zedoaria) 2%, 4%, 6% with a uniform toothpaste base. Evaluation of toothpaste preparations includes homogeneity, organoleptic, pH, dispersion and foam height tests. The test results of the three toothpaste preparations showed that the three formulations were homogeneous, there was no organoleptic change, the pH range of toothpaste from 6.5 to 8.0 which fulfilled the pH requirements of toothpaste according to SNI 12-3524-1995, namely 4.5 - 10, 5, the spreadability test range is 6.4 - 8.0 cm, and the foam height test range is 6.6 - 8.3 cm.

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