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All Journal Jurnal Kedokteran Diponegoro Media Medika Muda
Dhega Anindita Wibowo
Department Of Medical Biology And Biochemistry, Faculty Of Medicine, Universitas Diponegoro, Semarang, Indonesia
Medicine & Pharmacology

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THE EFFECT OF THE USE OF MASK ON THE INCIDENCE OF ACNE VULGARIS IN STUDENTS OF MEDICAL FACULTY DIPONEGORO UNIVERSITY Devy Kurniawati; Dhega Anindita Wibowo; Puguh Riyanto; Widyawati Widyawati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 1 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i1.32526

Abstract

Background: Acne vulgaris (AV) is an inflammatory condition of pilosebaceous follicles that is commonly experienced in adolescents and young adults. The pathogenesis of AV is multifactorial, such as caused by inflammation and external factors of acne exposome, which have an impact on the pathogenesis of acne in the use of masks.Objective: To determine the effect of using a mask and the number of acne vulgaris on students of the Faculty of Medicine, Diponegoro University.Methods: This research is an observational type with a cross sectional design. The research subjects were 58 students of the Faculty of Medicine, Diponegoro University with an age range of 19-23 years who used masks. The data obtained are primary data from the questionnaire. The analytical test used is bivariate chi square analysis.Results: This study showed that there was no significant effect between the type of mask and the incidence of acne vulgaris p 0.610 (p>0.05), the duration of the use of masks and the incidence of acne vulgaris p 0.200 (p>0.05), and the frequency of using masks with the incidence of acne vulgaris p 0.689. (p>0.05)Conclusion: There is no effect between the use of masks and the incidence of acne vulgaris.
UJI BANDING MANFAAT KRIM ESTRIOL 0,1% DAN KRIM ASTAXANTHIN 0,1 % TERHADAP KERIPUT KULIT SUDUT MATA PADA PRIA Dhega Anindita Wibowo; Diah Adriani Malik; ES Indrayanti; Meilien Himbawani; R Sri Djoko Susanto; S Buditjahjono
Media Medika Muda Vol 1, No 1 (2016)
Publisher : Faculty of Medicine Diponegoro University

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Latar belakang: Keriput pada awalnya mulai nampak pada sudut mata. Hal ini dikhawatirkan baik wanita maupun pria. Aktivitas sehari-hari yang tinggi diluar rumah tanpa perlindungan terhadap sinar matahari yang adekuat ditambah penipisan lapisan ozon dapat menimbulkan penuaan kulit dini. Salah satu cara mengurangi keriput dapat menggunakan estrogen dan astaxanthin topikal. Penelitian ini untuk membandingkan efektivitas pemberian krim estriol 0,1% dan krim astaxanthin untuk mengurangi keriput kulit sudut mata pada pria.Metode: Penelitian ini merupakan uji klinis one group pre and post test design tanpa blinding, melibatkan 13 subyek pria usia 40–50 tahun dengan keriput kulit pada sudut mata. Efektivitas estriol dan astaxanthin topikal dalam mengurangi jumlah dan kedalaman keriput kulit sudut mata dibandingkan, pengukuran dengan metode replika gips dan dinilai secara visual. Jumlah dan perbedaan penurunan jumlah keriput sudut mata dianalisis dengan uji Wilcoxon, perbedaan kategori penurunan jumlah dan kedalaman keriput dengan uji χ2, perubahan kategori penurunan jumlah dan kedalaman keriput awal sampai akhir penelitian dianalisis dengan uji Mc Nemar.Hasil: Penurunan jumlah keriput pada estriol 0,1% adalah tidak bermakna, sedangkan pada astaxanthin 0,1% adalah bermakna, dan perbedaan persentase penurunan jumlah keriput antara estriol dengan astaxanthin adalah bermakna. Perubahan skor kedalaman keriput pada estriol dan astaxanthin adalah bermakna, namun penurunan skor kedalaman keriput serta distribusi kategori responsif antara kedua sisi adalah tidak berbeda bermakna.Simpulan: Krim astaxanthin 0,1% lebih efektif menurunkan jumlah dan kedalaman keriput sudut mata pada pria dibanding estriol 0,1%.Kata kunci: estriol, astaxanthin, jumlah dan kedalaman keriput kulit sudut mata, pria
The Effects Of Purple Grape Juice (Vitis Vinifera) On Spermatozoa Motility Of Male Wistar Rats (Rattus Norvegicus) Exposed To Electric Cigarette Smoke Ishak Raharjo Putranto; Dhega Anindita Wibowo; RR Mahayu Dewi Ariani; Donna Hermawati
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 12, No 1 (2023): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v12i1.36490

Abstract

Background: Infertility in men can be caused by decreased motility of spermatozoa. Electric cigarette smoke containing nicotine can produce free radicals that cause a decrease in sperm motility. Purple grape juice which contains flavonoids can act as antioxidants that can increase the motility of spermatozoa. Objective: To prove the effect of administering purple grape juice on sperm motility of male Wistar rats exposed to electric cigarette smoke.Methods: This research is an experimental study with a post-test-only control group design. Sample consisted of 28 male Wistar rats divided randomly into 4 groups, namely negative control, positive control (given electric cigarette smoke), treatment one (given electric cigarette smoke + purple grape juice 3 mL/day), and treatment two (given electric cigarette smoke + purple grape juice 5 mL/day). The adaptation was carried out for 1 week, followed by treatment for 4 weeks, then the sperm of Wistar rats were collected and the sperm motility of Wistar rats was examined. Statistical test used Saphiro Wilk and Kruskal Wallis test.Results: Progressive motility rate of K(-), K(+), P1, P2 groups consecutively: 58.33 ± 7,52; 26,66 ± 8,16; 31,66 ± 7,52; 43,33 ± 12,11. Non progressive motility rate of K(-), K(+), P1, P2 groups consecutively: 26,66 ± 10,32; 55 ± 8,36; 43,33 ± 12,11; 35 ± 12,24. Immotility rate of K(-), K(+), P1, P2 consecutively: 18,33 ± 9,83; 28,33 ± 14,71; 20 ± 6,32; 16,66 ± 5,16. Kruskal Wallis test found a significant difference in progressive motility (p=0.002) and non-progressive motility (p=0.005).Conclusion: Purple grape juice affects sperm motility of male wistar rats exposed to electric cigarette smoke.
Co-Authors Devy Kurniawati Diah Adriani Malik Donna Hermawati ES Indrayanti Ishak Raharjo Putranto Meilien Himbawani Puguh Riyanto R Sri Djoko Susanto RR Mahayu Dewi Ariani S Buditjahjono Widyawati Widyawati