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Widyawati Widyawati
Department Of Dermatology And Venereology, Faculty Of Medicine, Diponegoro University, Semarang, Indonesia
Medicine & Pharmacology

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MELASMA SHOW UP IN CONTRACEPTIVE PILLS ACCEPTORS Cahya Novenita Azzahra; Widyawati Widyawati; Liza Afriliana; Julian Dewantiningrum
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i1.29436

Abstract

AbstractIntroduction : Melasma is one of the most common hyperpigmentation disorders among womans, the common hyperpigmentation patches which commonly found on face especially on sunlight exposured area. One of the factors causing melasma is the use of oral contraceptives which cause the buildup of the hormones estrogen and progesterone on the skin.Objectives : Thus, the aim of the study is to analyze the association between duration of contraceptive pills use and melasma.Methods : This study used a cross-sectional design. The research was conducted in May-July 2020. The subjects were 36 womans aged 30-55 years old and oral contraceptive acceptors that qualify inclussion criteria and not eligible exclussion criteria. The data was collected primarily using questionnaires. Physical examinations were done through observation with a photo of the respondents. Data analysis using the Chi Square test with a significance value p <0,05.Results : Based on the results of this study, the significance of 0.017 less than 0.05 which indicates a relationship between variables duration of contraceptive pills use and melasma. Conclusions : This study shows a association between duration of contraceptive pills use and melasmaKeywords : melasma, contraceptive pills.
THE EFFECT OF THE USE OF MASK ON THE INCIDENCE OF ACNE VULGARIS IN STUDENTS OF MEDICAL FACULTY DIPONEGORO UNIVERSITY Devy Kurniawati; Dhega Anindita Wibowo; Puguh Riyanto; Widyawati Widyawati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 1 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i1.32526

Abstract

Background: Acne vulgaris (AV) is an inflammatory condition of pilosebaceous follicles that is commonly experienced in adolescents and young adults. The pathogenesis of AV is multifactorial, such as caused by inflammation and external factors of acne exposome, which have an impact on the pathogenesis of acne in the use of masks.Objective: To determine the effect of using a mask and the number of acne vulgaris on students of the Faculty of Medicine, Diponegoro University.Methods: This research is an observational type with a cross sectional design. The research subjects were 58 students of the Faculty of Medicine, Diponegoro University with an age range of 19-23 years who used masks. The data obtained are primary data from the questionnaire. The analytical test used is bivariate chi square analysis.Results: This study showed that there was no significant effect between the type of mask and the incidence of acne vulgaris p 0.610 (p>0.05), the duration of the use of masks and the incidence of acne vulgaris p 0.200 (p>0.05), and the frequency of using masks with the incidence of acne vulgaris p 0.689. (p>0.05)Conclusion: There is no effect between the use of masks and the incidence of acne vulgaris.
THE EFFECT OF GLYCOLIC ACID AND VITAMIN C TOPICAL IN FRECKLES EFFICACY Tiffani Sandradewi Wignjosoesastro; Widyawati Widyawati; Rahmat Sugianto
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 1 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i1.29346

Abstract

Abstract Background: Freckles are small dark-spot hyperpigmentation on the face, upper body, and back of the hands. This hyperpigmentation develops as a result of melanocyte activity by the combination of genetic predisposition located on the basal layer and sun exposure. Glycolic acid and vitamin C are widely used as a depigmentation agent. The component of vitamin C is unstable, hence, it is often used more effective when it binds to other depigmentation agents, such as glycolic acid to develop better depigmentationObjective: The aim of this study was to prove the efficacy of combination of glycolic acid and vitamin C in freckles.Methods: True experimental study with one group pre and post-test group design. Fifteen freckles patients with inclusion and exclusion criteria received combination therapy of glycolic acid and vitamin C topical for 30 days. Clinical evaluation using Freckles Refinement Score and photography was recorded before and after therapy. The statistical analyses used was Wilcoxon test.Results: There was a significant value (p = 0.000) for improvement of the Freckles Refinement Score after received the combination of glycolic acid and vitamin C topical.Conclusion: The combination of glycolic acid and vitamin C was effective for Freckles. 
The Correlation Between The Use Of Face Moisturizers On The Incidence Of Acne Vulgaris Due To Masks Ashauma Aksanul Muttaqin; Ari Budi Himawan; Lusiana Batubara; Widyawati Widyawati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 4 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i4.35080

Abstract

Background: Acne vulgaris or widely known as acne, is a skin disease in the form of inflammation of the pilosebaceous unit characterized by the appearance of comedones, papules, pustules, and nodules. Due to the Coronavirus disease 2019 (COVID-19) pandemic, masks have become personal protective equipment (PPEs), commonly used by health workers and the general public. The combination of friction, repeated pressure, sweat, or stress on the skin from wearing the mask causes acne or an exacerbation of existing acne. Meanwhile, the use of facial moisturizer can maintain skin moisture and help the repair process of the structure of the skin barrier.Objective: This study aims to determine the relationship between the use of facial moisturizers and the incidence of acne vulgaris due to masks.Methods: This study is an analytical observational study with a cross-sectional design. The subjects in this study amounted to 44 people who were nurses at the Diponegoro National Hospital who had approved the informed consent form, filled out a complete questionnaire, and included the research criteria. The research sample was selected using purposive sampling. The diagnosis of acne vulgaris was made by doctor-in-charge based on the subject's face photo. The statistical test used is Fischer's Exact Test.Results: Based on data analysis using Fischer's Exact Test, the results showed no significant relationship between the use of facial moisturizers and the incidence of acne vulgaris due to masks with a p-value = 0.722 (p>0.05).Conclusion: There is no relationship between the use of facial moisturizers with the incidence of acne vulgaris due to masks.
Co-Authors Ari Budi Himawan Ashauma Aksanul Muttaqin Cahya Novenita Azzahra Devy Kurniawati Dhega Anindita Wibowo Julian Dewantiningrum Liza Afriliana Lusiana Batubara Puguh Riyanto Rahmat Sugianto Tiffani Sandradewi Wignjosoesastro