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All Journal Jurnal Insan Farmasi Indonesia Jurnal Bakti Untuk Negeri
Muhammad Reza Pahlevi
Sekolah Tinggi Ilmu Kesehatan Borneo Lestari
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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UJI AKTIVITAS ANTIPIRETIK FRAKSI n-HEKSAN KULIT BUAH JERUK NIPIS (Citrus aurantifolia (Christm.) Swing) MENGGUNAKAN INDUKSI VAKSIN DPT-HB-Hib PADA MENCIT JANTAN GALUR Balb/c Satrio Wibowo Rahmatullah; Eka Fitri Susiani; Muhammad Reza Pahlevi; Guntur Kurniawan; Khairina Maida
Jurnal Insan Farmasi Indonesia Vol 4 No 1 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i1.693

Abstract

Jeruk nipis adalah sejenis tanaman perdu yang banyak tumbuh dan dikembangkan di Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas fraksi n-heksan kulit buah jeruk nipis pada mencit yang diinduksi vaksin, membuktikan kemampuan antipiretik dari fraksi n-heksan kulit buah jeruk nipis pada mencit yang diinduksi vaksin dan mengetahui dosis fraksi n-heksan kulit buah jeruk nipis yang memiliki aktivitas sebagai antipiretik pada mencit yang diinduksi vaksin. Sebanyak 25 ekor mencit dibagi menjadi 5 kelompok, kelompok I kontrol positif (parasetamol), kelompok II kontrol negatif (Na-CMC 0,5%), kelompok III, IV, V diberikan fraksi n-heksan kulit buah jeruk nipis dengan dosis 0,07%/20gBB, 0,105%/20gBB dan 0,14%/ 20gBB. Kulit buah jeruk nipis mengandung senyawa saponin, tanin, alkaloid, triterpenoid/steroid, flavonoid dan kumarin yang memberikan aktivitas antipiretik Pengukuran suhu tubuh dilakukan sebelum pemberian induksi vaksin DPT-HB-Hib, dan 30 menit sekali setelah perlakuan sampai menit ke-180. Mencit diinduksi demam menggunakan vaksin DPT-HB-Hib secara intramuskular dengan dosis 0,01ml/gBB mencit. Data yang diperoleh dianalisis menggunakan uji ANOVA dan uji Independent T-Test. Kesimpulan dari penelitian ini bahwa fraksi n-heksan kulit buah jeruk nipis (C. aurantifolia (Christm.) Swing) mempunyai aktivitas antipiretik pada mencit jantan galur Balb-c dan pada konsentrasi 0,07%, 0,105%, dan 0,14% memiliki kemampuan aktivitas sebagai antipiretik yang tidak berbeda signifikan.
SOSIALISASI DAN EDUKASI PENCEGAHAN COVID-19 PADA ANAK USIA SEKOLAH DI TPA NOOR IMAN, SUNGAI BESAR, BANJARBARU SELATAN, KOTA BANJARBARU Nurul Mardiati; Muhammad Reza Pahlevi; Atni Primanadini
Jurnal Bakti untuk Negeri Vol 1 No 1 (2021)
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (184.086 KB)

Abstract

The coronavirus pandemic (COVID-19) has been declared a public health emergency or extraordinary event (KLB) and has spread to many countries and regions. The consequences of the COVID-19 pandemic are enormous and are felt by everyone around the world, including children who are growing and developing. In the Coronavirus Disease 2019 pandemic situation, which is abbreviated as COVID-19, every child without exception has the right to receive rights, protection, and clear information about the prevention and transmission of COVID-19. "Socialization and Education of COVID-19 Prevention for School-Age Children at TPA Noor Iman" is a health promotion activity for the movement of wearing masks, washing hands, and keeping a distance (3M) to prevent transmission of COVID-19. This community service activity was carried out at TPA Noor Iman Sungai Besar, Banjarbaru, South Kalimantan. This program is expected to become a medium to increase students' knowledge so that they can better understand COVID-19. Another goal, students can properly practice how to use masks and wash their hands according to WHO standards. This Community Service activity was carried out by filling in material about the causes, symptoms, and ways to prevent COVID-19. The media used are PowerPoints, videos, and props for dolls made of used socks and singing the COVID-19 jingle, which is a composition of the Rainbow song - familiar with children's daily lives. Furthermore, the children were also educated to properly practice how to use masks and wash their hands according to WHO standards. In the final session, the students who seemed to be the most active during the implementation of the program were then used as little ambassadors for COVID-19
Co-Authors Atni Primanadini Eka Fitri Susiani Guntur Kurniawan Khairina Maida Nurul Mardiati Satrio Wibowo Rahmatullah