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UJI AKTIVITAS GEL LENDIR BEKICOT (ACHATINA FULICA) SEBAGAI PENYEMBUHAN LUKA SAYAT Shoviantari, Fenita; Fajriyah, Shofiatul; Agustin, Ela; Khairani, Shafia
Jurnal Ilmiah As-Syifaa Vol 13, No 1 (2021): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jifa.v13i1.648

Abstract

Snail mucus (Achatina fulica) has a high protein content, which includes beta agglutinin, achasin protein, acharan sulfate, and glycoconjugate. The objectives of this study was to determine differences in physical evaluation of the quality of the gel preparation against snail mucus concentration and to determine the efficacy of snail mucus gel as a wound healing. This study used an experimental research method with a sample of 4 male rats (Rattus novergicus) which were divided into 6 groups in each. The results showed that there was no effect of the physical quality of snail slime gel (Achatina fulica) on the concentration of snail slime formulated. It has been proven in the Kruskall wallis statistical test with the Sig. > 0.05. The results of the wound healing activity test showed an average value of K (+) 49.61%, K (-) 17.48%, P1 48.23%, P2 43.63%, P3 43.43%, and P4 23, 97. Values that indicate differences in K (-) and P4 are evidenced in the Post Hoc LSD test with Sig. <0.05. It can be concluded that the concentration of snail mucus does not affect the physical quality of snail mucus gel preparations and snail mucus gel with snail mucus concentration of 10% is effective in the process of wound healing.
UJI IRITASI GEL LENDIR BEKICOT (Achatina fulica) SECARA HISTOPATOLOGI Shofiatul Fajriyah; Fenita Shoviantari; Binti Nurkayati; Shafia Khairani; Lia Agustina
Jurnal Wiyata Penelitian Sains dan Kesehatan Vol 7, No 2 (2020)
Publisher : LP2M IIK (Lembaga Penelitian dan Pengabdian Masyarakat Institut Ilmu Kesehatan) Bhakti Wiy

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Abstract

Latar Belakang: Lendir bekicot (Acahtina fulica) mengandung glikokonjugat kompleks yaitu glikosaminoglikan dan proteoglikan yang memiliki banyak fungsi diantaranya dapat menyembuhkan luka. Salah satu syarat sediaan topikal yang baik adalah tidak mengiritasi kulit. Sediaan topikal yang mengiritasi kulit justru akan memperparah kondisi pada kulit. Tujuan: Penelitian ini bertujuan untuk mengetahui uji mutu fisik dan efek iritasi dalam sediaan gel dari perbedaan konsentrasi lendir bekicot. Metode: Lendir bekicot diformulasikan dalam bentuk sediaan gel menggunakan gelling agent karbopol 940 dengan perbedaan konsentrasi dari lendir bekicot 10%, 15%, dan 20%. Hasil: Hasil penelitian menunjukkan bahwa tidak adanya pengaruh mutu fisik sediaan gel dengan perbendaan konsentrasi lendir bekicot. Hasil uji iritasi secara mikroskopis dari skor indeks pada preparat histologi kulit tikus jantan yang diwarnai dengan Hematoxillyn eosin menghasilkan bahwa sediaan gel pada formula 1 dan 2 sedikit mengiritasi serta pada formulasi 3 menghasilkan sediaan gel dengan iritasi sedang. Simpulan: dari hasil penelitian dapat disimpulkan bahwa perbedaan konsentrasi lendir bekicotengan rentang 10 – 20% tidak mempengaruhi hasil uji mutu fisik dan penggunaan lendir bekicot sampai dengan kadar 15% aman digunakan.
The Use of Prophylactic Antibiotics for Cesarean Section Delivery and The Incident of Surgical Site Infection Shofiatul Fajriyah; Umul Farida; Sri Agustina; Lelly Winduhani Astuti; Esti Ambar Widyaningrum
Indonesian Journal of Pharmaceutical Education Vol 3, No 2 (2023): Mei-Agustus 2023
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v3i2.19864

Abstract

According to the 2018 Riskesdas data, the ratio of deliveries by cesarean section in 2018 was recorded at 17.6% of a total of 78,736 deliveries. One of the serious problems in postoperative treatment that has an impact on increasing morbidity, mortality, and increasing medical costs is surgical site infection (SSI). To reduce the risk of infection, efforts are made by giving prophylactic antibiotics followed by surgical procedures. The aim of this study was to determine the use of prophylactic antibiotics in cesarean section surgery and to determine the incidence of surgical site infection (SSI) in patients after Sectio Caesarea surgery in one of a private hospital in Kediri City. This study was an observational descriptive study with retrospective data collection through tracing of medical record data of patients who underwent Caesarean section surgery in 2021. The samples that entered the inclusion criteria were patients who received surgical prophylaxis with antibiotics and returned to the hospital for control after 1 week postoperatively. Samples that met the inclusion criteria were 89 patients. The sampling technique used purposive sampling. This study collected data on prophylactic antibiotics used and the incidence of SSI on days 1, 3 and (7-10) postoperatively.  The results showed that the types of prophylactic antibiotics in patients undergoing sectio caesarea were ceftriaxone 2 g (99%) and cefotaxime 2 g (1%). Whereas there were 3 patients (3%) who had SSI on days 7-10 postoperatively.
Patterns of Antihistamin and Corticosteroids Usage In Dermatitis Patients At Primary Public Health Center in Jombang: Pola Penggunaan Antihistamin dan Kortikosteroid Pada Pasien Dermatitis di Puskesmas Kabupaten Jombang Shofiatul Fajriyah; Dea Justisia Ayu Nandya; Erni Anikasari; Fenita Shoviantari
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 8 No. 2 (2023): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v8i2.328

Abstract

Dermatitis or eczema is a form of the condition in which the layers of the skin (epidermis and dermis) have general inflammation which is usually influenced by endogenous and exogenous factors causing clinical abnormalities in the form of polymorphic efflorescence (erythema, edema, papules, vesicles, scales, lichenification) and itching complaint. This study simed to determine the treatment pattern given to patients with atopic dermatitis and contact dermatitis at the Jelakombo Health Center Jombang. This was an observational study with retrospective data collection. The data sourced used was existing medical records from January to December 2020. Data analysis was carried out descriptively with purposive sampling. The results showed that the most common dermatitis patients were atopic dermatitis (34%) which mostly treated with CTM+Dexamethasone. Patients with allergic contact dermatitis were 38 patients (38%), the most common drug regimen to manage it was Cetirizine+Hydrocortisone ointment. There were 28 patients (28%) with irritant contact dermatitis, which mostly treated with Cetirizine+Hydrocortisone Ointment followed by CTM + Dexamethasone. This study concluded that the drug regimen for the three types of dermatitis was almost the same, namely a combination of oral and topical antihistamines and corticosteroids. The antihistamines used were first-generation antihistamines (CTM) and second-generation (Cetirizine and Loratadine). Further assessment related to whether the sedation effect was wanted or it was disturbing side effect is needed. The widely used oral corticosteroid was dexamethasone, which is a high-potency corticosteroid, so its use must be judicious. Topical corticosteroids were hydrocortisone ointments that include low potency topical corticosteroids which are the first line of atopic dermatitis and allergic contact dermatitis.
Hubungan Tingkat Stres Pengobatan Terhadap Kadar Gula Darah Penderita Diabetes Melitus Tipe 2 Di Puskesmas Kota Kediri Umul Farida; Shofiatul Fajriyah; Ayu Kusuma; Adisty Berlia Prameswari
Jurnal Farmasi SYIFA Vol 1 No 1 (2023): Jurnal Farmasi SYIFA
Publisher : CV. Wadah Publikasi Cendekia

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Abstract

Diabetes mellitus merupakan penyakit autoimun dimana terdapat gangguan metabolisme tubuh kronis ditandai dengan fungsi insulin yang tidak mencukupi, berakibat pada meningkatnya kadar gula darah serta gangguan metabolisme dari karbohidrat, lipid, dan protein. Komplikasi dan kompleksnya penanganan yang dialami pasien dapat mempengaruhi status psikologis pasien. Salah satu hal yang bisa muncul adalah stres. Pada tahun 2021, 537 juta orang di seluruh dunia hidup dengan diabetes. Prevalensi diabetes di Indonesia adalah 2%. Pada 2019, jumlah penderita diabetes di Kota Kediri mencapai 9.435. Tujuan dari penelitian ini yakni untuk mengetahui gambaran dan hubungan antara tingkat stres pengobatan dan kadar gula darah pada pasien diabetes di Puskesmas Kota Kediri dengan menggunakan metode observasi analitik dan cross sectional. Data dikumpulkan secara prospektif menggunakan alat bantu pengambilan data berupa kuesioner. Penelitian ini menggunakan teknik sampling jenis quota sampling. Dengan menggunakan SPSS25 untuk menganalisis data, ditemukan bahwa 7 orang (8%) memiliki tingkat stres berat, 41 orang (47,2%) memiliki tingkat stres sedang, 39 orang (44,8%) tidak memiliki tingkat stres, dan 25 orang memiliki darah buruk. kadar gula darah (28,7%), 26 orang (29,9%) dengan kadar gula darah sedang dan 36 orang (41,4%) dengan kadar gula darah baik. Uji korelasi Spearman rho rank memberikan nilai signifikansi P-value 0,000 < 0,05 dan nilai koefisien korelasi 0,76 dari hasil tersebut disimpulkan bahwa antara 2 variabel yang diteliti memiliki hubungan yang signifikan dengan tingkat korelasi hubungan yang kuat.
Analysis Of Patient Perceptions, Awareness, Experience And Expectations Of The Role Of Pharmacist In Counseling Service At Pharmacies Dyah Ayu Kusumaratni; Eko Yudha Prasetyo; Indah Srihartini; Shofiatul Fajriyah; Widhi Astutik; Aprillia Putri G.R
Jurnal EduHealth Vol. 15 No. 02 (2024): Jurnal eduHealt, Edition April - June , 2024
Publisher : Sean Institute

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Abstract

Counseling services are a form of communication between pharmacists and patients in pharmaceutical services with the aim of increasing patient understanding of drug use and preventing medication errors. The presence of pharmacists is very necessary to be able to meet the diverse demands of society to be able to provide information regarding the correct use of medicines so that they can increase public knowledge. The interactions that occur between pharmacists and patients in counseling services will have an influence on public assessment. This research was conducted with the aim of knowing patients' perceptions, awareness, experiences and expectations of the role of pharmacists in counseling services in pharmacies. Method: The research is descriptive with a cross sectional design with a purposive sampling technique, the number of subjects involved was 143 respondents. Descriptive data analysis and normality test. Results: showed that 67.13% of patients had good awareness. As many as 53.14% of patients had a good perception. Then as many as 100% of patients had good hopes, and as many as 72.02% of patients had good experiences. Conclusion: the overall category shows the percentage of patients who have good perceptions, awareness, expectations and experiences regarding the role of pharmacists in counseling services in pharmacies.
POLA PERESEPAN OBAT PADA PASIEN MYALGIA DI PUSKESMAS NGANJUK Shofiatul Fajriyah; Erni anikasari
JURNAL PHARMA BHAKTA Vol 4 No 1 (2024): Mei 2024
Publisher : FAKULTAS FARMASI, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

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Abstract

Latar belakang: Myalgia paling sering dikaitkan dengan keseleo atau kaku otot. Gejala yang sering muncul adalah kemerahan di lokasi cedera, nyeri tekan, bengkak, dan demam. Nyeri otot adalah masalah medis utama dimana mayoritas (60% hingga 85%) dari populasi pernah mengalami nyeri punggung (nonspesifik). Tujuan: Penelitian ini bertujuan untuk mengetahui pola pengobatan pada pasien myalgia di Puskesmas Nganjuk Tahun 2020. Metode: Metode deskriptif observasional dengan pengumpulan data secara retrospektif. Penelitian ini menggunakan data rekam medis pasien myalgia dengan teknik sampling yaitu total sampling. Analisis data dilakukan secara deskriptif dan disajikan dalam bentuk prosentase. Hasil: Hasil penelitian menunjukkan sebanyak 39 pasien didiagnosa myalgia. Jenis analgesik yang digunakan adalah Asam Mefenamat, Natrium Diklofenak, Metampiron, Parasetamol dan Ibuprofen. Suplemen yang digunakan pada pasien myalgia adalah Kalsium Laktat, Vitamin B kompleks, vitamin B1, Multivitamin dan Ferrous fumarat. Pola pengobatan pasien myalgia meluputi analgesik tunggal (20,5%), kombinasi 2 analgesik (10,3%), kombinasi analgesik + suplemen (66,7%) dan kombinasi 2 suplemen (2,5%).  Simpulan : Pola peresepan obat yang paling banyak adalah kombinasi Asam Mefenamat dan Kalsium Laktat