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Nyoman Fitri
Pusat Biomedis dan Teknologi Kesehatan Dasar. Badan Litbang Kesehatan. Kemenkes RI
Chemistry Medicine & Pharmacology

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Profil Penggunaan Obat Antiinflamasi Nonstreoid di Indonesia Soleha, Maratu; Isnawati, Ani; Fitri, Nyoman; Adelina, Rosa; Soblia, Hamim Tsalis; Winarsih, Winarsih
Jurnal Kefarmasian Indonesia VOLUME 8, NOMOR 2, AGUSTUS 2018
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v8i2.316

Abstract

Nonsteroid Antiinflamation Drugs (NSAIDs) are available in drug store and be bought as a pain relief. Basic Health Research (Riskesdas) 2013 study the medicines stored in household. Basic Health Research (Riskesdas) 2013 was held in 33 provinces and 497 districts in Indonesia. The research encompasses 300.000 households in 12.000 blocks cencus. The participants were designated households and its member of the family. The study were interviewing the participants to obtain data of all drugs that are stored and used, including traditional medicines. The data including the brand, indication, the provenance (prescribed or unprescribed by doctor), the storage period and also observe drug condition. This study was further analysis of subset data in block IV of Riskesdas 2013 in households. The data were classified by its mechanism and its structure. The result showed that East Java was the highest user of AINS drugs was (15%). Non selectif COX-2 drug and partial selectif COX-2 was 38,3% bought from drug store and 14,4% from drug store. For rheumatism treatment was all used for more than a month. Widely use of NSAIDs as a pain relief indicated the necessity of a proper medicine use information to avoid side effect of NSAID drug.
Antimicrobial Peptides sebagai Obat Alternatif pada Resistensi Antibiotik Fitri, Nyoman
Jurnal Kefarmasian Indonesia VOLUME 2 NOMOR 2, AGUSTUS 2012
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

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Abstract

Antibiotic resistance has become a global public-health problem, thus it is imperative that new antibiotics have to be developed continously. Antimicrobial peptides (AMPs) are component of the innate immune response, which is the principal defence system for the majority of living organisms. Similar to antibiotics, most AMPs have a broad antimicrobial spectrum and highly active against fungi. AMPs are known to have interaction with biomembranes to lyse microbial cells. Many researches have tried to develop AMPs as future drugs for antibiotic resistance. Many AMPs also possess antiviral or anti-parasite activity. However, antimicrobial peptides have their own disadvantages. We review the role of these molecules in human’s health, their advantages and disadvantages as alternative antimicrobial for antibiotic resistance.
Butylated hydroxyanisole sebagai Bahan Aditif Antioksidan pada Makanan dilihat dari Perspektif Kesehatan Fitri, Nyoman
Jurnal Kefarmasian Indonesia VOLUME 4. NOMOR 1 FEBRUARI 2014
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v4i1.2899

Abstract

Butylated hydroxyanisole (BHA) is widely used since 1947 as antioxidant food additives used to prevent oils, fats and shortenings from oxidative deterioration and rancidity. It has been extensively studied for potential activities and its toxicities. This review summarized experimental studies that had been carried out on animals and humans as well. We also briefly reviewed about its absorptions, metabolisms, excretions and carcinogenicity from health perspective. At present there is sufficient evidence for carcinogenicity of BHA, but there is hardly any indication that BHA is genotoxic. Keywords: Butylated hydroxyanisole, Additive, Ef
Co-Authors Ani Isnawati Maratu Soleha Rosa Adelina Soblia, Hamim Tsalis Winarsih Winarsih