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Gidion Franklin Simorangkir
Universitas Prima Indonesia
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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POTENSI ANTIOKSIDAN DAN ANTI-ELASTASE EKSTRAK DAUN KELOR (MORINGA OLEIFERA) TERHADAP ANTIAGING Glorio ias Natanael; Gidion Franklin Simorangkir; Nanda Parariski Purba; Mardiana Putri br. Tambunan; Ali Napiah Nasution; Adek Amansyah
Jurnal Keperawatan Priority Vol. 4 No. 1 (2021)
Publisher : Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jukep.v4i1.1432

Abstract

Skin aging caused by oxidative stress that leads to the formation of wrinkles, pigmentation, and asteatosis. On the other hand, the elastase enzyme also can influence the elasticity of the skin that leads to sagging. Moringa leaves (Moringa oleifera Lamk) has been reported contain some active compounds like flavonoid that has antioxidant and anti-aging potential. This study was presented to determine the potential of moringa leaves extract (MLE) in scavenging DPPH radicals and inhibiting the elastase enzyme. MLE was obtained by using maceration methods. The potential of MLE in scavenging DPPH radicals and inhibiting elastase enzyme was determined using spectrophotometric methods. MLE has IC50 value of DPPH scavenging activity also elastase inhibitory activity at 109.67 + 0.83 µg/mL and 159.67 + 7.95 µg/mL. MLE has antioxidant and anti-aging potential as indicated by DPPH scavenging activity and elastase inhibitory. However, MLE has moderate DPPH scavenging activity and low elastase inhibitory activity.
Co-Authors Adek Amansyah Ali Napiah Nasution Glorio ias Natanael Mardiana Putri br. Tambunan Nanda Parariski Purba