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All Journal Pelita - Jurnal Penelitian Mahasiswa UNY Walisongo Journal of Chemistry JKPK (Jurnal Kimia dan Pendidikan Kimia) ALKIMIA : Jurnal Ilmu Kimia dan Terapan Jurnal Inovasi Teknik Kimia

Ika Nur Fitriani

Unknown Affiliation

Author-ID : 267126

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Environmental Science Social Sciences

Published : 6 Documents Claim Missing Document

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Articles

DEKOLORISASI SENYAWA AZO LIMBAH REMAZOL GOLDEN YELLOW OLEH BIOADSORBEN ECENG GONDOK (EICHHORNIA CRASSIPES) Fitriani, Ika Nur; Puspitasari, Anggi Ristiyana; Amelia, Rizki Nor
Walisongo Journal of Chemistry Vol 2, No 2 (2019): Walisongo Journal of Chemistry
Publisher : Department of Chemistry Faculty of Science and Technology Walisongo

Telah dilakukan penelitian tentang adsorbsi senyawa azo Remazol Golden Yellow dari limbah cair zat warna sintetis menggunakan adsorben dari eceng gondok (Eichhornia crassipes). Penelitian ini bertujuan untuk mengetahui kondisi optimal eceng gondok (Eichhornia crassipes) sebagai bioadsorben limbah zat warna Remazol Golden Yellow dan mengetahui kadar ppm Remazol Golden Yellow maksimum dalam limbah zat warna sintetis yang dapat diserap oleh bioadsorben eceng gondok (Eichhornia crassipes). Subyek penelitian adalah eceng gondok yang teraktivasi NaOH 2% dengan waktu perendaman 24 jam. Obyek penelitian adalah efisiensi adsorpsi eceng gondok (Eichhornia crassipes) terhadap zat warna sintetis-reaktif Remazol Golden Yellow. Variabel bebas yang dipakai adalah variasi massa. Daya adsorbsi ditentukan dengan dengan membandingkan konsentrasi Remazol Golden Yellow sebelum dan setelah adsorbsi. Hasil penelitian menunjukkan bahwa semakin besar massa bioadsorben, efisiensi adsorbsi juga akan semakin besar dan adsorbsi optimum variasi massa Remazol Golden Yellow diperoleh pada massa adsorben 2,5 gram/100 mL dengan efisiensi adsorbsi 74,767%

Molecular Docking Study of Nutmeg (Myristica Fragrans) Constituents as Anti-Skin Cancer Agents Fitriani, Ika Nur; Ansory, Hery Muhamad
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 6, No 1 (2021): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v6i1.47223

Molecular docking analysis was carried out to understand better the interaction between DHODH and inhibitor from nutmeg in this series. The nutmeg constituent binding orientations in the active site of DHODH was seen in a molecular docking analysis and helped design a potentially new inhibitor. This work aimed to study the molecular docking of nutmeg constituents with the DHODH inhibitor using a computer-aided drug design. Molecular docking using AutoDock 4.2 was done to explore the models of binding complexes. The 3D structure was derived using Discovery Studio to investigate the essential chemical interaction of complex structures. Dihydroguaiaretic acid was the most potent ligand having a docking score of -9.3 kcal/mol. This value was better than the standard drug 5-FU. The dihydroguaiaretic acid structure interacted with Tyr365 and Thr63 through a hydrogen bond similar to the native ligand. These results suggest that nutmeg seed could serve as the lead compound for potent DHODH inhibitors against skin.

“SWEET PAPAYA SEED CANDY” ANTIBACTERIAL ESCHERICHIA COLI CANDYWITH PAPAYA SEED (CARICA PAPAYA L.) Tika Pangesti; Ika Nur Fitriani; Firdiawan Ekaputra; Andi Hermawan
Pelita - Jurnal Penelitian Mahasiswa UNY Volume VIII, Nomor 2, Agustus 2013
Publisher : Pelita - Jurnal Penelitian Mahasiswa UNY

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (173.809 KB)

This research is experimental research aims to knowing how to made papayaseed candy as antibacterial in Escherichia coli and knowing inhibition zone of sweetpapaya seed candy against bacteria E. coli. This research give alternative new productof healthy food and improve economic value of papaya seed (Carica papaya L.)The process in this research has for ways: making papaya seed powder, makingjelly candy, making solution candy, and testing the bacterial growth inhibition zone ofEscherichia coli bacteria. This proses was held for two days in “Balai LaboratoriumKesehatan Yogyakarta”Result of this research is papaya seed can be processed to made papaya seedcandy by dried and refined. Beside on the bacterial growth inhibition testing, papayaseed candy didn’t have inhibition zone against Escherichia coli bacteria.

ANALISIS KADAR NITROGEN (N) DALAM PUPUK NPK REAKSI PT. PETROKIMIA GRESIK MENGGUNAKAN METODE IN HOUSE DAN SNI-INOVASI Nida Awalia; Ika Nur Fitriani
Jurnal Inovasi Teknik Kimia Vol 5, No 2 (2020)
Publisher : Fakultas Teknik Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/inteka.v5i2.3813

Potential Phytochemical Inhibitor from Allium cepa for the Medication of COVID-19 using In-Silico Approach Fitriani, Ika Nur; Utami, Wiji
ALKIMIA Vol 4 No 2 (2020): ALKIMIA
Publisher : SCIENCE AND TECHNOLOGY FACULTY OF UNIVERSITAS ISLAM NEGERI RADEN FATAH PALEMBANG

Infection of extreme acute respiratory syndrome coronavirus 2 triggers Coronavirus disease 2019 (COVID-19). COVID-19 has adverse consequences on persons and is getting worse in all nations. The aim of this research is to investigate the development of in-silico approach of phytochemical inhibitor used to fight COVID-19 pathway inhibition. In medicinal plants, there are many phytochemicals, however the bioactive mechanism remains uncertain. In-silico experiments offer additional evidence to confirm the inhibition of medicinal plants. Molecular docking was used to evaluate phytoconstituents from Allium cepa as COVID-19 M-pro inhibitor, compared to remdesivir (standard drug). STITCH database used to predict the interaction network process of the most potential compound. The most potential compound was oleanolic acid. Oleanolic acid with a docking score of -9.20 kcal/mol was reported as anti-COVID-19 activity. This docking score was higher than remdesivir. Oleanolic acid interacted with GLU166, CYS44, HIS41, and THR25 via the hydrogen bond. From STITCH Database, oleanolic acid interact with CASP-9, XIAP, CASP-3 signalling pathway. Oleanolic acid from Allium cepa has been reported as a possible COVID-19 M-pro inhibitor and should be studied in future studies. The experiment indicates that phytochemical inhibitor can be helpful in the medication of COVID-19.

Uji Analisis Kadar Sulfur (S) Pupuk SP-36 PT Petrokimia Menggunakan Metode In-House dan Inovasi Fitrani, Salsa; Fitriani, Ika Nur
ALKIMIA Vol 4 No 2 (2020): ALKIMIA
Publisher : SCIENCE AND TECHNOLOGY FACULTY OF UNIVERSITAS ISLAM NEGERI RADEN FATAH PALEMBANG

Fertilizer is an essential component in increasing food self-sufficiency in Indonesia. PT Petrokimia Gresik is one of the fourth-largest fertilizer producers in Indonesia and produces various kinds of fertilizers. One of the fertilizer is SP-36, contains sulphur and phosphate. This study investigated the sulphur (S) content in SP-36 fertilizer using the in-house and innovation method. The difference between the two methods is BaCl2; the in house method used BaCl2 powder, while the Innovation method used liquid BaCl2. Different used of BaCl2 were based on their colloid formation. This study used a UV-Vis spectrophotometer instrument to calculate the sulphur content of SP-36 fertilizer. The results obtained from the research show that the two methods tested can be used to measure the sulphur content in SP-36 fertilizer. The most accurate result was In house method. The average value of sulphur content in SP-36 fertilizer using the in house method is 4,83%, while the average value of sulphur content in SP-36 fertilizer using the innovation method is 5,22%.

Co-Authors Andi Hermawan Firdiawan Ekaputra Fitrani, Salsa Muhamad Ansory, Hery Nida Awalia Puspitasari, Anggi Ristiyana Rizki Nor Amelia Tika Pangesti Wiji Utami

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