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Journal : Indonesian Journal of Tropical and Infectious Disease

A STUDY OF CORRELATION BETWEEN AGENT, HOST, ENVIRONMENT AND VACCINE FACTORS WITH PREVALENCE OF RABIES IN INDONESIA 2015 Tyas Ika Budi Setyowati; Putri Bungsu Machmud
Indonesian Journal of Tropical and Infectious Disease Vol. 7 No. 1 (2018)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (607.389 KB) | DOI: 10.20473/ijtid.v7i1.6556

Abstract

A zoonotic disease has been global threat related to health and one of them is rabies. More than 150 countries around the world has infected by rabies disease problem and the case fatality rate (CFR) reaches 100%, which there are 55,000 people died every year because of rabies. In Indonesia, there are 25 from 34 province, which has endemic of rabies disease. The purpose of this study is to know the correlation between the factors of the agent, host, and environment and also anti rabies vaccine with the prevalence of rabies in Indonesia at 2015. The study used correlation design which using Indonesian zoonotic reported data by Ministry of Health and also used other secondary data, which is provided by central bureau of statistic Indonesia (BPS).  The provinces that included in this study are the endemic provinces associated with the rabies incident that reported to Ministry of Health and have the completeness of data in 2015. A total of 22 provinces was included in this study, which only use Rabies cases from dog’s bite only. Rabies that source from others animal’s bite could not included in this study because of data limitations. This study used simple linear of regression statistical tests through provincial as unit analysis. The result of this study showed that there were correlations between agent that have positive specimens (r=0.606, P value =0.0003), status of working participation rate (r=0.435, P value 0.004) and also coverage of rabies vaccine (r=-0.567, P value =0.041) with the prevalence of rabies disease. In summary, there are a positive correlation between positive specimen of agent and also status of working participant rate with the prevalence of rabies disease. However, rabies vaccine coverage has negative correlation. Furthermore, there is no correlation between environment factors and prevalence of rabies disease in this study. It still need further research to be more research on a smaller level with variables that varied.
DETERMINANT FACTORS OF DROP OUT (DO) AMONG MULTI DRUGS RESISTANCE TUBERCULOSIS (MDR TB) PATIENTS AT JAKARTA PROVINCE IN 2011 TO 2015 Sitti Farihatun; Putri Bungsu Machmud
Indonesian Journal of Tropical and Infectious Disease Vol. 7 No. 3 (2018)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.158 KB) | DOI: 10.20473/ijtid.v7i3.7793

Abstract

The prevalence of Drop out (DO) among Multi Drugs Resistant Tuberculosis (MDR TB) patients increases every year in Jakarta Province. The latest data of 2016 contains 367 drug resistant TB patients and 78 patients (21.2%) were DO. This study was aimed to analyze the determinant factors of Drop Out (DO) among MDR TB patients in Jakarta Province between 2011 to 2015 based on risk factors of age, sex, HIV status, sputum test, type of patient, number of previous treatments and number of drugs resistance. This study was used secondary data that source from cohort registration e-TB Manager from DKI Jakarta Health Office with total 516 samples. The design study was an observational cross sectional quantitative study. DO is a condition of patients who have been treated and drop out of treatment for 2 consecutive months or more. The crude prevalence of DO among MDR TB patients was 44.6%. Trend of DO among MDR TB was increased since 2011 to 2015. There was a further increase more than 10% in every year. The proportion of DO among MDR TB in Jakarta was more than 64 years old (63.6%), male (47.3%), patients with status HIV negative (44.9%), patients that never or ever consumed drugs less than 1 month (61.2%), and patients with >2 drugs resistance (45.7%). The results of this study indicated that proportion of DO among MDR TB patients at Jakarta Province in 2011-2015 was high. Therefore, it is necessary efforts that can decrease DO cases among MDR TB patients. This study was expected to be a reference for Jakarta Province Health Office in implement P2TB Program implementation and reach target precisely.