Sudarno Sudarno
Universitas Airlangga

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Red Dragon Fruit Extract (Hylocereus polyrhizus) Restores Learning Ability and Memory on Test Animals Post Lead Exposure: Experimental Study on Test Animals Made Pury Pratiwi; Raden Argarini; Sudarno Sudarno
ANIMA Indonesian Psychological Journal Vol. 30 No. 1 (2014): ANIMA Indonesian Psychological Journal (Vol. 30, No. 1, 2014)
Publisher : Laboratory of General Psychology, Faculty of Psychology, Universitas Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (396.723 KB) | DOI: 10.24123/aipj.v30i1.535

Abstract

The aim of this study was to analyze whether red dragon fruit (Hylocereus polyrhizus) administration affect learning ability and memory after lead exposure. A randomized control-group pretest-posttest was conducted with 24 mice (Mus musculus), which was divided through a random assignment into four groups: G1, G2, G3, and G4. Group G1 received 1.16 mg/10 g BW lead acetate. Group G2, G3, and G4 received 1.16 mg/10 g BW lead acetate and red dragon fruit extract 250 mg/kg BW (G2), 500 mg/kg BW (G3), and 1000 mg/kg BW (G4). Results revealed that some groups that has been given red dragon fruit extract (group G2, G3, and G4) showed significant improvement of latency time, frequency, and combined scoring value of latency time and frequency in posttest by using Morris Water Maze compared to the control group (p = .001; α = .05). The improvement of group G3 and G4 was better than group G2. These finding indicates that administration of red dragon fruit extract have a protective effect and improves learning ability and memory after lead exposure with 500-1000 mg/kg BW as the best dose.
The Addition of Lemuru Fish Oil in Bran Suspension to Successful Induction of M. macrocopa Ephippia Production Reni Oktaviani; Ahmad Shofy Mubarak; Sudarno Sudarno
Journal of Aquaculture and Fish Health Vol. 9 No. 1 (2020): JAFH Vol. 9 no. 1 February 2020
Publisher : Department of Aquaculture

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (335.106 KB) | DOI: 10.20473/jafh.v9i1.15443

Abstract

The production M. macrocopa ephippia limited by availability of poly unsaturated fatty acids (PUFAs) in feed. The lack amount of ω-3 fatty acids in rice bran suspension limits ephippia production. Lemuru fish oil containing EPA has potential to enrich in rice bran suspension to increase ephippia production. The purpose of this study to determine the affect addition of lemuru fish oil in rice bran suspension and the optimal concentration of lemuru fish oil in rice bran suspension which results the highest ephippia production. This study used Completely Randomized Design (CRD) method with 5 treatments adding fish oil in rice bran suspension of 0%, 1.5%, 3%, 4.5%, and 6%), with 4 replications. Sexual female offspring are produced from cultures with density 660 ind /L with regulated feed concentration. Furthermore, offspring are cultured with feed according the treatment. During the culture, daily production, total production and production ephippia per  parent. These results indicate addition of lemuru fish oil to rice bran suspension as feed of  M. macrocopa affect the production ephippia. The addition of lemuru fish oil with concentration  6ml / 100g in rice bran produce the highest total M. macrocopa ephippia production  (3452 ± 43.0 grains / Liter)