Sang Sanggita Surya
Universitas Islam Indonesia

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Aktivitas antibakteri metabolit sekunder lalat rumah Musca domestica terhadap Staphylococcus aureus ATCC 25923 Sang Sanggita Surya; Farida Juliantina Rachmawaty
Jurnal Kedokteran Syiah Kuala Vol 20, No 3 (2020): Volume 20 Nomor 3 Desember 2020
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jks.v20i3.18377

Abstract

Abstrak. Lalat merupakan serangga yang dapat membawa berbagai bakteri, salah satunya Staphylococcus aureus. Bakteri tersebut dapat menyebabkan penyakit pada manusia. Hadits Nabi Muhammad s.a.w disebutkan bahwa lalat memiliki penyakit pada satu sisi sayapnya dan penawar pada sisi sayap yang lain. Hasil penelitian ini diharapkan dapat mengetahui gambaran hadits tersebut dan peran metabolit sekunder lalat rumah terhadap pertumbuhan Staphylococcus aureus. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri metabolit sekunder lalat rumah terhadap Staphylococcus aureus serta mengetahui konsentrasi bakteri yang dapat dihambat oleh metabolit sekunder tersebut. Metode penelitian yang digunakan adalah eksperimental laboratorium dengan menguji aktivitas antibakteri metabolit sekunder lalat rumah yang diambil pada menit ke-20 terhadap Staphylococcus aureus yang terbagi menjadi 6 konsentrasi yaitu 101 CFU/ml hingga 106 CFU/ml. Hasil dianalisis secara deskriptif dengan membandingkan pertumbuhan bakteri pada uji metabolit sekunder dengan kontrol. Hasil pengujian didapatkan terdapat hambatan pertumbuhan Staphylococcus aureus pada uji metabolit sekunder lalat rumah dibandingkan dengan kontrol. Konsentrasi yang dapat dihambat sepenuhnya adalah 101 CFU/ml, sedangkan konsentrasi 102 CFU/ml hingga 106 CFU/ml dihambat sebagian. Namun hasil yang diperoleh belum konsisten. Metabolit sekunder lalat rumah memiliki aktivitas antibakteri terhadap Staphylococcus aureus yaitu ditunjukkan oleh hambatan pertumbuhan bakteri pada semua konsentrasi yang diuji Kata Kunci: Aktivitas Antibakteri, Metabolit           Sekunder, Musca   domestica, Staphylococcus aureus Abstract. Flies are insects carry a variety of bacteria, one of it is Staphylococcus aureus. This bacterium cause disease in humans. However, in the hadith of the Prophet Muhammad s.a.w, mentioned that a fly carries a disease on one side of its wings and an antidote on the other side. Therefore, the results of this study are expected to be able to explain the relation with the meaning of the hadith of the Prophet Muhammad s.a.w. and to show the role of secondary metabolites of houseflies on the growth of Staphylococcus aureus. This research is to determine the antibacterial activities of the housefly’s secondary metabolites towards Staphylococcus aureus and the concentration of bacteria that can be inhibited by these secondary metabolites. This research use experimental laboratory which tested the antibacterial activities of the housefly’s secondary metabolites taken in the 20th minute towards Staphylococcus aureus, was divided into six concentrations of 101 CFU/ml to 106 CFU/ml compared with controls. The results were analyzed descriptively by comparing bacterial growth in secondary metabolites test with bacterial growth in control. This research found there is Staphylococcus aureus growth inhibition in the test given secondary metabolites of house flies compared with controls. Concentrations of bacteria that can be inhibited entirely are 101 CFU/ml, while those that can be partially inhibited are at concentrations of 102 CFU/ml to 106 CFU/ml. But the results obtained have not consistent. Secondary metabolites of house flies have antibacterial activity towards Staphylococcus aureus. This is indicated by the inhibition of bacterial growth at all concentrations tested.Keywords: Antibacterial activity, secondary metabolites, Musca domestica, Staphylococcus aureus
Anemia in Pregnancy and Low Birth Weight Before and During the COVID-19 Pandemic in Kalijambe Sang Sanggita Surya; Nur Aisyah Jamil; Dwi Cahyanti; Aulia Rahma; Amalia Adityas D. S; Tika Minawati Dewi
Media Kesehatan Masyarakat Indonesia Vol. 17 No. 4: DECEMBER 2021
Publisher : Faculty of Public Health, Hasanuddin University, Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (386.16 KB) | DOI: 10.30597/mkmi.v17i4.18206

Abstract

Pregnant women and infants were a vulnerable group during the COVID-19 pandemic. This research aimed to determine anemia in pregnancy and Low Birth Weight (LBW) before and during the COVID-19 pandemic and analyze their associated factors. This was a cross-sectional study used secondary data from maternal and child health records in Kalijambe Public health center, Sragen. A total of 1169 birth records from the period of 2019-2020 were collected. The chi-square and logistic regression were used to analyze the differences and significant associated factors. The prevalence of anemia in pregnancy increased from 38.33% in 2019 to 49.21% in 2020 (p=0.013). However, the LBW proportion decreased from 7.26% in 2019 to 6.02% in 2020 (p=0.415). Mother who suffered from chronic energy deficiency marked by Mid-Upper Arm Circumference (MUAC) < 23.5 cm was higher risk of anemia (aOR 1.86;95%CI 1.13-3.08). Considering the gestational age when the hemoglobin (Hb) test, anemia was more likely to be found at the second (aOR 2.59;95%CI 1.37-4.86) and third trimester (aOR 6.97;95%CI 3.98-12.20). High-risk pregnancy had higher odds of LBW (aOR 8.57;95%CI 1.65-44.37), while anemia showed no effect on LBW (aOR 1.80;95% CI 0.34-9.45). These results were adjusted for mothers’ age, parity, abortus, infection during pregnancy, high-risk pregnancy, MUAC, preterm birth, and gestational age. COVID-19 pandemic increased the prevalence of anemia in pregnancy but had no impact on LBW. Several factors for anemia and LBW were significantly associated. This finding suggests the need for early risk detection and routine, standardized, and comprehensive antenatal care.