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All Journal Jurnal Kedokteran Syiah Kuala Bioscientia Medicina : Journal of Biomedicine and Translational Research Biomolecular and Health Science Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research
Bambang Soeprijanto
Department Of Radiology, Faculty Of Medicine Universitas Airlangga, Surabaya, Indonesia - Dr. Soetomo General Hospital Surabaya
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Kanker Paru dan Penatalaksanaannya Arief Bakhtiar; Bambang Soeprijanto
Jurnal Kedokteran Syiah Kuala Vol 6, No 1 (2006): Volume 6 Nomor 1 April 2006
Publisher : Universitas Syiah Kuala

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Abstract

Abstr  ak.  Keluhan    kanker  paru   terjadi   akibat   kelainan   :  intra  pulmonal,    intra  torasik    ekstra  pulmonal, ekstra   torasik    metastatik,     ekstra  torasik   non  meiastatik.     Prosedur   diagnosa    meliputi    deteksi   dini   dan tindakan   diagnostik    lebih   Ianjut    yang secara  garis  besar dapat dibagi  dua :  Tindakan  Non  lnvasif  ( CT­ Scan   Toraks,   Positron Emission Tomography (PET)   Magnetic Resonance Imaging);  dan  tindakan invasif    (Transthoracic   Needle  Aspiration,   Fiber  Optik  Bronkoscopi,      Endoscopic      Ultrasound, Mediastinoskopi).      Klasifikasi    kanker  paru jenis   karsinorna    bukan   sel  kecil  berdasarkan   TNM  staging, sedangkan   small cell lung carsinoma berdasarkan   Veterans  Administrasion      Lung  Cancer  Study  grup. Penatalaksanaan     kanker  paru  bersifat   multimodalitas      terapi   yang   terdiri   dari:    pernbedahan,     radiasi, kernoterapi,    irnunoterapi,   terapi  hormonal   dan tempi  gen.  (JKS 2006;1:23-38) Kata   kunci   :  karsinorna  bron.kogenik,    diagnose,    penatalaksanaan. Abstract.  Lung  cancer  is  caused  by  intra­pulmonary,      intra­thoracic     extra­pulmonary,     extra­thoracic metastatic,     and  extra  thoracic   non­metastatic     abnormalities.     The  diagnosis    procedure   includes    early detection   and  further  diagnostic   action   which are divided  into  two: Non­Invasive     Action  (Thoracic   CT­ Scan,     Positron     Emission       Tomography     (PET),      Magnetic      Resonance     Imaging)     and    invasive (Transthoracic        Needle       Aspiration,         Fiber     Optical       Bronchoscopy,       Endoscopic       Ultrasound, Mediastinoscopy).     The  classification   of carcinoma  lung  caricer of non­small  cell  carcinoma    is  based  on TNM  staging,   whereas  small  cell  lung  Veterans  Administrasion     carcinoma    is  based  on Lung  Cancer Study  Group.  The  treatment   of lung  cancer  is identi   lied as multi modality  therapy  consisting   of surgery,radiation,    chemotherapy,   irnrnunotherapy,     hormonal   therapy and gene  therapy.  (JKS 2006;1:23-38) Keywords: carcinoma bronchogenic, diagnosis, treatment.
Diagnostic Value of CT Angiography (CTA) in Carotid Cavernous Fistula (CCF) Patients Using the Digital Subtraction Angiography (DSA) as The Gold Standard: Observation in Dr. Soetomo General Hospital Surabaya from January 2016 to July 2020 Laila Amalia; Hartono Yudi Sarastika; Bambang Soeprijanto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 6 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i6.318

Abstract

Background: CT angiography (CTA) is the initial modality for diagnosing the Carotid Cavernous Fistula (CCF), identifying the type of CCF, measuring the diameter of the fistula and the diameter of the internal carotid artery (ICA) pre and post fistula, and then confirmed by Digital Subtraction Angiography (DSA) as the gold standard. CTA is expected to provide more information to improve the accuracy of CCF diagnosis to benefit therapy and prevent complications. This study aimed to determine the diagnostic value of CTA in CCF patients in Dr. Soetomo General Hospital Surabaya, using the DSA as a gold standard. Methods: An observational retrospective study of CCF patients met the inclusion and exclusion criteria and underwent CTA and DSA examinations at the Radiology Installation of Dr. Soetomo General Hospital, Surabaya, from January 2016 to July 2020. Results: In the comparison of types of CCF CTA to DSA, the direct group was 53.8% and 57.7%, respectively, while the indirect group was 46.1% and 42.3% with a very strong correlation (κ = 0.922; p = 0.000), sensitivity was 93.3%, specificity was 100 %, PPV of 100%, NPV of 91.7% and accuracy of 96.15%. Direct type evaluation on the DSA showed a large picture of the fistula diameter; the ICA pre fistula's size was enlarged; therefore, the ICA post fistula diameter was reduced or absent. There was a strong correlation of fistula diameter measurement results between CTA and DSA (r = 0.695, p = 0.006). Conclusion: CTA has a similarity rate of 92.2% with DSA in identifying the type of CCF. The accuracy value of CTA is close to DSA in fistula diameter measurements.
Head Computed Tomography Images of HIV/AIDS Patients with Suspected Cerebral Toxoplasmosis in Dr. Soetomo General Hospital Surabaya Ria Wibawani; Bambang Soeprijanto; Widiana Ferriastuti; Erwin A Triyono
Biomolecular and Health Science Journal Vol. 2 No. 1 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.739 KB) | DOI: 10.20473/bhsj.v2i1.13343

Abstract

Introduction: Toxoplasma gondii is an intracellular pathogenic parasite with the majority of co-infections occurring in HIV/AIDS patients. This study assesses the head computed tomography (CT) images of cerebral toxoplasmosis in patients with HIV/AIDS.Methods: This study was a cross-sectional design using head CT images of 35 HIV/AIDS patients with suspected cerebral toxoplasmosis. Variables include lesion type, location, size, CD4 count, and therapeutic result with anti-cerebral toxoplasmosis. All data analysed descriptively.Results: From total 110, 35 patients met the inclusion criteria. 24 patients (68.6%) were male and 11 (31.4%) female, average age, was 36.1. 8 patients (22.3%) had lesions in cortical, 31 patients (88.6%) had < 1 cm lesion. Single lesions mainly calcified and found in the right centrum semiovale while multiple lesions were subcortical. A hypodense lesion with rim or nodular contrast enhancement is found in 75% of patients with CD4 > 200 in contrast to slight rim contrast enhancement and perifocal edema in patients with CD4 < 200. 20 patients (57.4%) had improved condition after anti-toxoplasmosis therapy.Conclusion: Cerebral toxoplasmosis lesions in HIV/AIDS patients have various types of imaging findings, mostly multiple, with most frequent location being cortical and diameter < 1 cm. Total recovery is achieved in the majority of patients with therapy.
The Correlation between Apparent Diffusion Coefficient Value on MRI and the Pathology Consistency of Meningioma Wyka Faulani Hafizah Nur; Widiana Ferriastuti; Bambang Soeprijanto
Biomolecular and Health Science Journal Vol. 3 No. 2 (2020): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v3i2.22171

Abstract

Introduction: Preoperative evaluation of meningioma consistency is important because it will affect surgical procedures, surgical optimization, risk assessment, and patient management. The consistency of meningioma can be predicted by Apparent Diffusion Coefficient (ADC) value on MRI. ADC values are useful in quantitative tumor assessment based on diffusivity in the tumor. The objective of the study is to find out the correlation between ADC value and the pathology consistency of meningioma.Methods: A retrospective study was carried out using medical records at Dr. Soetomo General Hospital, Surabaya by January 2017 - December 2018. The ADC value was obtained by placing three ROI in the tumor and the consistency was obtained from the results of the pathology examination, followed by the Spearman correlation test.Results: There The tumor range value of ADC was 0.58 x 10-3mm2 s to 1.63 x 10-3mm2/s. The mean ADC value in soft, intermediate, and hard consistency was 1.247+ 0.200 x 10-3mm2/s, 0.950 + 0.453 x 10-3mm2/s, and 0.793 + 0.161 x 10-3mm2/s, the cut-off value of ADC was + 0.822 x 10-3mm2/s with specificity 68% and sensitivity 85%, the AUC is 0.740 with a significance value of 0.0043 (p<α, α = 0.05). It was obtained an ADC correlation with the consistency of meningioma, the significance value is p=0.000 (p<α, α = 0.05).Conclusion: There is a correlation between the ADC value and the consistency of meningioma. The ADC value can be considered for an optimal preoperative evaluation in assessing the consistency of meningioma.
Diagnostic Value of CT Angiography (CTA) in Carotid Cavernous Fistula (CCF) Patients Using the Digital Subtraction Angiography (DSA) as The Gold Standard: Observation in Dr. Soetomo General Hospital Surabaya from January 2016 to July 2020 Laila Amalia; Hartono Yudi Sarastika; Bambang Soeprijanto
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 5 No. 6 (2021): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bsm.v5i6.318

Abstract

Background: CT angiography (CTA) is the initial modality for diagnosing the Carotid Cavernous Fistula (CCF), identifying the type of CCF, measuring the diameter of the fistula and the diameter of the internal carotid artery (ICA) pre and post fistula, and then confirmed by Digital Subtraction Angiography (DSA) as the gold standard. CTA is expected to provide more information to improve the accuracy of CCF diagnosis to benefit therapy and prevent complications. This study aimed to determine the diagnostic value of CTA in CCF patients in Dr. Soetomo General Hospital Surabaya, using the DSA as a gold standard. Methods: An observational retrospective study of CCF patients met the inclusion and exclusion criteria and underwent CTA and DSA examinations at the Radiology Installation of Dr. Soetomo General Hospital, Surabaya, from January 2016 to July 2020. Results: In the comparison of types of CCF CTA to DSA, the direct group was 53.8% and 57.7%, respectively, while the indirect group was 46.1% and 42.3% with a very strong correlation (κ = 0.922; p = 0.000), sensitivity was 93.3%, specificity was 100 %, PPV of 100%, NPV of 91.7% and accuracy of 96.15%. Direct type evaluation on the DSA showed a large picture of the fistula diameter; the ICA pre fistula's size was enlarged; therefore, the ICA post fistula diameter was reduced or absent. There was a strong correlation of fistula diameter measurement results between CTA and DSA (r = 0.695, p = 0.006). Conclusion: CTA has a similarity rate of 92.2% with DSA in identifying the type of CCF. The accuracy value of CTA is close to DSA in fistula diameter measurements.
Co-Authors Bakhtiar, Arief Erwin A Triyono Faradilla litiloly1, Hartono Yudi Sarastika1 Laila Amalia Ria Wibawani Widiana Ferriastuti Wyka Faulani Hafizah Nur