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Postpartum Coccydynia: an Anatomy Overview Reza Maulana; Nur Wahyuniati; Imai Indra
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 5, No 2 (2015): Life Sciences
Publisher : Syiah Kuala University

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Abstract

Coccydynia is a term that refers to a painful condition in and around the coccyx. This symptom is typically a discomfort or pain which is felt when sitting for long time and when rising from sitting position. Many physiologic and psychological factors contribute to its etiology, but the majority of cases were found to be aggravated by pregnancy and childbirth (postpartum). Luxation and fracture of the coccyx are the two most common lesion of postpartum coccydynia. This poster shows an anatomy overview especially the coccyx to increase the understanding about this symptom
Inflammation and the Migration of Mesenchymal Stem Cell Reza Maulana; Nur Wahyuniati; Imai Indra
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 5, No 2 (2015): Life Sciences
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (508.969 KB)

Abstract

Mesenchymal stem cells are adult non-hematopoietic stem cells with multilineage proliferation and differentiation capabilities. This type of stem cell has the multipotent ability to differentiate into osteocytes, tenocytes, adipocytes, chondrocytes and  bone marrow stromal cells. The migration mechanism of mesenchymal stem cell is not yet fully understood, but based on studies  that  have  been  done  recently  by  the  researchers  worldwide  shown  that  the inflammatory process plays an important role for mesenchymal stem cell migration. A number of chemokine that plays a role in the migration of mesenchymal stem cells such as MCP-1 (CCL2), CXCL8, RANTES (CCL5), LL-37, integrin β1, CD44 receptor, CCR2, CCR3, and tyrosine kinase receptors for the following growth factors: IGF -1, PDGF-bb, HGF and VEGF
Pharmacologic Aspect of Neuropathic Pain Endang Mutiawati; Imai Indra; Syahrul Syahrul; Mulyadi Mulyadi
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 5, No 2 (2015): Life Sciences
Publisher : Syiah Kuala University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (401.767 KB)

Abstract

Neuropathic pain is pain arising from nerve damage to the conductive pathways of pain (ranging from nociceptors to post central gyrus). Neuropathic pain can be caused by 1) Carcinomas, 2) Trap/compressive, 3) Congenital, 4) Immunomediated, 5) Infection, 6) Metabolic disorders, 7) nutritional deficiency, 8) Toxin, 9) Lesion, 10) Vasculitis, 11). Connective tissue disorders. To date, the pathophysiology of neuropathic pain can not be explained thoroughly, this problem leads to the treatment which has not given satisfactory results as expected. There are many types of drugs has been used for the treatment of neuropathic pain, and they are generally aimed to stop the flow of impulses in the nervous system which was activated as a result of ectopic generators in areas experiencing nerve injury. These drugs work in several locations such as: drugs that works on 'sodium channel  voltage  gate'  (i.e  Carbamazepine  group),  drugs  that  works  on  'calcium  channel'  (i.e Gabapentin and Pregabalin), and also drugs that works on ‘the synapses gap’ (i.e Tricyclic class). Besides drugs that inhibit pain impulses propagation, the treatment of neuropathic pain also include drugs that have the ability of nervous system regeneration such as methylcobalamin group. The rationale of the use of this kind of drugs is that this drug expected to regenerate the damage of the nervous system damage which is lead to decrease the ectopic generator activity, the end result is the reducement of neuropathic pain experienced by patients
Pre-Anesthesia Assessment and Preparation Imai Indra; Kulsum Kulsum
Budapest International Research in Exact Sciences (BirEx) Journal Vol 2, No 2 (2020): Budapest International Research in Exact Sciences, April
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v2i2.977

Abstract

The aims of the study is to find out pre – anesthesia assessment and preparation. The result of the study shows that Pre-anesthesia is an important first step in a series of anesthesia procedures performed on patients who are planned to undergo surgery. The things that need to be done include history taking, physical examination, laboratory examination, and physical status classification. Preparations are made at the clinic or at home for outpatients, in the treatment room, in the Central Surgery Installation (IBS) room, and in the operating room. Pre-anesthesia physical status assessment is very important. Anesthesia is not differentiated based on the size of the surgery but consideration of the choice of anesthesia techniques that will be given to patients is very complex and comprehensive considering all types of anesthesia have risk factors for complications that can threaten the patient's life