Endang Mutiawati Rahayuningsih*
Department Of Neurology, School Of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Department Of Neurology, Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia

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DIAGNOSIS DAN STRATEGI PENANGANAN NYERI LEHER FOKUS PADA MIELOPATI SPONDILOSIS Endang Mutiawati Rahayuningsih*
NEURONA Vol 33 No 1 Desember 2015
Publisher : Neurona Majalah Kedokteran Neuro Sains

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PAIN IS A TERM USED TO EXPRESS THE PRESENCE OF PAIN IN THE BACK OF THE NECK AREA BOTH LOCALLY AND RADIATING TO THE OCCIPITAL SHOULDERS AND ARMS THE MAIN CAUSES OF NECK PAIN INCLUDE DEGENERATIVE PROCESSOF THE CERVICAL SPINE VERTEBRAL BODIES JOINTS LIGAMENTS INTERVERTEBRAL DISCS RADICULOPATHY AND MYELOPATHY RARELY NECK PAIN CAN BE CAUSED BY TRAUMA NEOPLASM AND OTHER DISORDERS
EVALUASI BLOK SENDI FASET LUMBAL PADA NYERI PUNGGUNG BAWAH KRONIK AKIBAT KELAINAN SENDI FASET Dessy Rakhmawati Emril,* Devi Inkha,* Endang Mutiawati,* Nova Dian Lestari,* Thomas Eko Purwata**
NEURONA Vol. 33 No. 3 Juni 2016
Publisher : Neurona Majalah Kedokteran Neuro Sains

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INTRODUCTION CHRONIC LOW BACK PAIN LBP REMAINS THE IMMENSE PROBLEM FACED BY DOCTORS NOWADAYS LUMBAR FACET JOINT HAS BEEN SHOWN AS THE SOURCE OF CHRONIC PAIN IN 21 TO 41 OF LOW BACK PAIN PATIENTS
Perbandingan Daya Ingat Anak Pada Sekolah Dasar Negeri Dan Sekolah Dasar Islam Terpadu Desrina Desrina; Endang Mutiawati; Rusli Yusuf
Jurnal Ilmu Keperawatan Vol 6, No 1 (2018): Jurnal Ilmu Keperawatan (JIK) VI No.1 Januari-Juni 2018
Publisher : Jurnal Ilmu Keperawatan

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Abstract

Kualitas  bangsa  di  masa  depan  ditentukan  oleh  kualitas  anak-anak  saat  ini.  Agar  memperoleh  pertumbuhan  dan perkembangan  anak  usia  sekolah  yang  optimal  maka  perlu  diperhatikan  asupan  nutrisi  baik  secara  kualitas  maupun kuantitas.  Dalam  masa  pertumbuhan  dan  perkembangan  tersebut  pemberian  nutrisi  atau  asupan  makanan  pada  anak tidak  selalu  dilakukan  dengan  sempurna.  Desain  penelitian  ini  adalah  kuantitatif  dengan  metode  komparatif.  Populasi dalam  penelitian  ini  adalah  anak  sekolah  dasar.  Teknik  pengambilan  sampel yang  digunakan quota  sampling berjumlah20  orang.  Hasil  uji  daya  ingat  anak  dari  ketiga  uji  daya  ingat  yang  dilakukan  pada  10  anak  SD  Negeri  tidak  ada  yangmemilki  skor  yang  tinggi,  sedangkan  untuk  SD  IT  dari  10  anak  yang  di  uji  daya  ingat  terdapat  anak  yang  memiliki  skortinggi,  pada  media  angka  terdapat  6  orang  (60%),  3  orang  (30%)  dan  1  orang  (10%)  pada  game  gadget.  Hasil  uji perbedaan diatas diketahui kolom T-Tes for Equality of Means pada variabel faktor individu, lingkungan dan daya ingat memiliki nilai  signifikan   0,05 (p   0,05),  faktor individu sebesar  0.007,  faktor lingkungan 0,026 dan daya ingat sebesar 0.015  dimana semua  nilai  variabel    0,05,  berarti  terdapat  perbedaan.  Sedangkan  untuk  faktor  objek  nilai  signifikan sebesar 0.717 (P0.05) yang artinya tidak terdapat perbedaan antara faktor objek SD Negeri dengan SD IT.Kata Kunci : Perbandingan, daya ingat, sekolah negeri dan sekolah swasta.AbstractThe nation quality in the future is determined by the quality of the kids on this period. In order to achieve optimal growth of the kids at the school age, it is needed to  focus on the  nutrition on the kids which is probably cannot well given.  The design  of  this  study  is  quantitative  with  comparative  methods.  The  population  is  the  elementary  scho ol  students.  The sampling  technique  used  by  quota  sampling  was  20  people.  The  results  of  the  students's  memory  test  from  the  three memory tests were carried out on 10 public elementary school students, none of whom had a high score, while for the SD IT of 10 students who were tested for memory there were children who had a high score, in the media figures there were 6 students (60%), 3 students (30%) and 1 student (10%) in the gadget game. The results of the difference test above note that  the  T-Test  for  Equality  of  Means  column  on  the  variables  of  individual,  environmental  and  memory  factors  has  a significant value 0.05 (p 0.05), individual factors are 0.007, environmental factors are 0.026 and memory is 0.015 where all  variable  values are  0.05,  meaning  there  are  differences.  Whereas  for  the  object  factor  significant  value  is  0.717  (P0.05)  which  means  there  is  no  difference  between  the  object  factors  of  islamic  school  and  basic  school  of  elementary school.Keywords: Comparison,Memory, Public Schools and Private Schools
HUBUNGAN KESIAPSIAGAAN DOKTER PUSAT KESEHATAN MASYARAKAT KOTA BANDA ACEH DENGAN MOTIVASI PENANGANAN PASIEN KECELAKAAN LALU LINTAS Syahrizal Syahrizal; Endang Mutiawati; Mudatsir Mudatsir; Imran Imran; Syahrul Syahrul; Mulyadi Mulyadi
Jurnal Kedokteran Syiah Kuala Vol 16, No 3 (2016): Volume 16 Nomor 3 Desember 2016
Publisher : Universitas Syiah Kuala

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Pharmacologic Aspect of Neuropathic Pain Endang Mutiawati; Imai Indra; Syahrul Syahrul; Mulyadi Mulyadi
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 5, No 2 (2015): Life Sciences
Publisher : Syiah Kuala University

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Neuropathic pain is pain arising from nerve damage to the conductive pathways of pain (ranging from nociceptors to post central gyrus). Neuropathic pain can be caused by 1) Carcinomas, 2) Trap/compressive, 3) Congenital, 4) Immunomediated, 5) Infection, 6) Metabolic disorders, 7) nutritional deficiency, 8) Toxin, 9) Lesion, 10) Vasculitis, 11). Connective tissue disorders. To date, the pathophysiology of neuropathic pain can not be explained thoroughly, this problem leads to the treatment which has not given satisfactory results as expected. There are many types of drugs has been used for the treatment of neuropathic pain, and they are generally aimed to stop the flow of impulses in the nervous system which was activated as a result of ectopic generators in areas experiencing nerve injury. These drugs work in several locations such as: drugs that works on 'sodium channel  voltage  gate'  (i.e  Carbamazepine  group),  drugs  that  works  on  'calcium  channel'  (i.e Gabapentin and Pregabalin), and also drugs that works on ‘the synapses gap’ (i.e Tricyclic class). Besides drugs that inhibit pain impulses propagation, the treatment of neuropathic pain also include drugs that have the ability of nervous system regeneration such as methylcobalamin group. The rationale of the use of this kind of drugs is that this drug expected to regenerate the damage of the nervous system damage which is lead to decrease the ectopic generator activity, the end result is the reducement of neuropathic pain experienced by patients
METHYLCOBALAMIN EFFECT ON MECHANICAL BEHAVIOR ALLODYNIA IN RATS SPRAGUE DAWLEY ENDANG MUTIAWATI
Proceedings of The Annual International Conference, Syiah Kuala University - Life Sciences & Engineering Chapter Vol 4, No 2 (2014): Life Sciences
Publisher : Syiah Kuala University

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Abstract

Neuropathic pain is an expression of the nerve damage that impaired its excitability, such as increased excitability in the nerve lesion and surrounding healthy nerves as well. It is estimated that the incidence of neuropathic pain ranges between 2-40% of all adult men. Some neuropathic pain can not be cured, such as in patients with diabetes mellitus, trigeminal neuralgia, cervical syndrome, carpal tunnel syndrome, lumbar stenosis, herniated nucleus pulposus and the carcinoma. The pathophysiology of neuropathic pain are complex and not fully understood. Methylcobalamin is a metabolite of vitamin B12 acts as a coenzyme in the formation of methionine from homocysteine. This reaction is useful in the formation of DNA, as well as maintenance of nerve function. Through the methylation reaction, methylcobalamin also plays a role in the formation of lecithin, a protein that plays an important role in the regeneration of peripheral nerves, including the formation of myelin. This study aimed to determine animal mechanical alodinia with or without the administration of methylcobalamin. Twenty male Sprague Dawley rats, aged 2 months, with an average weight of 150-250 g, obtained from the Laboratory LPPT Gadjah Mada University, Yogyakarta. The mice were randomly divided into 4 groups, each consisting of 5 mice. All the rats, their fifth lumbar nerve were ligated. Group I was the control mice (C) 0.9% NaCl given, group II (M1) were given a dose of 50 microg methylcobalamin, group III (M2) were given a dose of 100 microg methylcobalamin, while group IV (M3) were given a dose of 150 microg methylcobalamin 13 weeks provision. For 13 weeks, neuropathic pain behavior was assessed. Neuropathic pain behavior in experimental animals observed about onset, duration and filaments Von Frey numbers that cause mechanical alodinia. Result of the study showed methylcobalamin influence the mechanical alodinia. Based on the results obtained, it is concluded that there was a reduction in neuropathic pain in the methylcobalamin group compared with the control group.
PENGUATAN PERAN POSYANDU DALAM MENINGKATKAN KETAHANAN MASYARAKAT TERHADAP BENCANA TSUNAMI DI WILAYAH PESISIR KOTA BANDA ACEH MENGGUNAKAN PENDEKATAN KNOWLEDGE MANAGEMENT Eka Sartika; Khairul Munadi; Endang Mutiawati
Jurnal Ilmu Kebencanaan : Program Pascasarjana Unsyiah Vol 4, No 4: November 2017
Publisher : Jurnal Ilmu Kebencanaan : Program Pascasarjana Unsyiah

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The lack of disaster knowledge is one of the causes of the high casualties of women in the tsunami in Banda Aceh. Strengthening the posyandu's role in improving community resilience to disasters is essential. Research’s purpose is to identify posyandu role, strengthen posyandu role by analyzing the factors that become supporter and challenge faced by posyandu, and to initiate effective efforts in building disaster resilient community through Knowledge Management(KM) approach. The research uses quantitative and qualitative approach. Determination of sample by purposive involving 6 Posyandu located in coastal area of Banda Aceh City. Data were collected with questionnaires, in-depth interviews and focus group discussions. Analysis technique used is thematic analysis method. The results revealed that 77.8% of Posyandu managers have disaster knowledge at the medium level. Posyandu has many supporting factors to act as the agent of disaster knowledge dissemination. Strengthening the posyandu's role needs to be realized by continuous KM approach,  its strategy is to make the program regularly disseminate disaster knowledge, build Posyandu community network with non-formal learning facilities so that it can give input to policy and program in achieving development sustainable in  Banda Aceh.Key words :  Tsunami,  Posyandu, and  Knowledge Management
SCN1A exon 26 variants in epilepsy and migraine patients Nova Dian Lestari; Endang Mutiawati; Ahmad Hamim Sadewa; Hasan Sjahrir; . Syahrul; Dessy Rakhmawati Emril; . Harapan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 50, No 4 (2018)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (331.556 KB) | DOI: 10.19106/JMedScie/005004201806

Abstract

Epilepsy and migraine are common neurological diseases in many populations. Mutation of the voltage gated natrium channel Nav1.1 (SCN1A) are important causes of different genetic epilepsies and can also cause familial hemiplegic migraine (FHM-III). This study aimed to identify SCN1A gene variation in patients with epilepsy and common migraine. Gene variation analysis of exon 26 of the SCN1A gene was carried out in 33 patients with epilepsy, 33 patients with migraine and 30 control individuals from Neurology Polyclinic at Dr. Zainoel Abidin General Hospital, Banda Aceh. The PCR and direct sequencing methods were performed in this study. SCN1A gene variations were identified in two epilepsy patients. These gene variations located at exon 26 were four silent mutations in patient E27 at position A4440T (Leu1480Leu), T4443C (Leu1481Leu), A5046G (Leu1682Leu) and C5121T (Asp1707Asp). One silent mutation in patient E30 at position G5505A (Glu1835Glu). None of these gene variations were identified in controls and patients with common migraine in this study. This study has identified 5 genetic variations of SCN1A in patients with epilepsy but not in common migraine. The mechanism and relationship between these variants and epilepsy need to be clarified.
The Clinical Characteristics of Patients with Embolic Strokes among Indonesian Subjects Syahrul; Imran; Farida; Suherman; Nasrul Musadir; Nurul Fajri; Endang Mutiawati; Nova Dian Lestari
Britain International of Exact Sciences (BIoEx) Journal Vol 2 No 3 (2020): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v2i3.296

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Stroke accounts for 10% of the world's deaths and causes severe long-term disabilities. Twenty-six million people world wide experience a stroke each year. Two-thirds represents cerebral ischemia. Age, a history of stroke or transient ischemic attack, hypertension, diabetes and heart failure characterize a stroke. Early detection with a proper treatment could improve clinical outcomes in such cases.
Hubungan Derajat Stroke Terhadap Status Kognitif Pada Pasien Stroke Iskemik Di Poliklinik Saraf Rumah Sakit Umum Daerah dr. Zainoel Abidin Banda Aceh Mafruzah Nanda Putri; Endang Mutiawati; Wilda Mahdani
Jurnal Ilmiah Mahasiswa Kedokteran Medisia Vol 2, No 1: Februari 2017
Publisher : Jurnal Ilmiah Mahasiswa Kedokteran Medisia

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Abstract

Stroke merupakan suatu penyakit serebrovaskular akibat penurunan atau terhentinya aliran darah ke otak. Penderita stroke biasanya akan mengalami kerusakan fungsi kognitif tergantung dengan derajat stroke yang dideritanya. Tujuan penelitian ini adalah untuk mengetahui hubungan derajat stroke terhadap status kognitif pada pasien stroke iskemik di Poliklinik Saraf RSUD dr. Zainoel Abidin Banda Aceh. Jenis penelitian ini adalah analitik observasional dengan desain cross sectional yang dilakukan pada bulan Oktober sampai Desember 2016.Penelitian ini menggunakan instrumen National Institutes of Health Stroke Scale (NIHSS) dan Mini Mental State Examination (MMSE).Data dianalisis dengan menggunakan uji korelasi Spearman. Sampel berjumlah 40 orang yang terdiri dari 24 orang (60,0%) pria dan 16 orang (40,0%) wanita dengan karakteristik responden usia diantara 56-65 tahun sebanyak 21 orang (52,5%), lulusan SMA sebanyak 20 orang (50,0%), memiliki riwayat hipertensi sebanyak 21 orang (52,5%) dan riwayat merokok sebanyak 22 orang (55,0%). Hasil penelitian didapatkan 22 orang (55,0%) mempunyai derajat stroke sedang dan 19 orang (47,5%) mengalami gangguan kognitif ringan. Terdapat hubungan yang kuat antara derajat stroke dengan status kognitif (p = 0,000, r = 0,603). Kesimpulannya terdapat hubungan yang kuat antara derajat stroke terhadap status kognitif pada pasien stroke iskemik di Poliklinik Saraf RSUD dr. Zainoel Abidin Banda Aceh.