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Hasti Yuliani
UBI Farmakologi-Toksikologi, FMIPA-ITB
Mathematics

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Efek Teratogenik Ekstrak Etanol Kulit Batang Pule (Alstonia scholaris R.Br) pada Tikus Wistar Endang Kumolosasi; Andreanus A. Soemardji; Komar Ruslan W.; Hasti Yuliani
Jurnal Matematika & Sains Vol 9, No 2 (2004)
Publisher : Institut Teknologi Bandung

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Abstract

The teratogenic effect of ethanolic extract of “pule” (Alstonia scholaris R.Br., Apocynaceae) bark at repeated doses of 490 and 980 mg/kg body weight administered orally to pregnant Wistar rats for 19 days had been studied. Each dose caused miscarriage in 9.1% of the rats and mild hydrocephalus in 23.1% of the fetuses (dose 490 mg/kg body weight) and in 12.0% of the fetuses (dose 980 mg/kg body weight).
Co-Authors Andreanus A. Soemardji Endang Kumolosasi Komar Ruslan W.