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Yusup Subagio Sutanto
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Medicine & Pharmacology

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Hubungan Status Ekonomi dan Tingkat Pengetahuan TB Dengan Keterlambatan Pasien Dalam Diagnosis Kasus TB Paru Caesaria Sarah Selleca; Yusup Subagio Sutanto; . Reviono
Nexus Kedokteran Komunitas Vol 2, No 1 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Lately, there are a lot of TB cases with late diagnosis. Economic status and knowledge are one of many factor that could lead to late diagnosis in patient with pulmonary tuberculosis. This study aims to know the risk factors of economic status and knowledge to the incidence of TB patient with late diagnosis. Subject and Methods:This study used an observational analytic cross-sectional study approach (cross-sectional). It was held on May to August 2012 in Balai Besar Kesehatan Paru Masyarakat (BBKPM) Surakarta. The research subjects are 60 patient with new cases of pulmonary TB sampled by consecutive sampling method. The subjects were asked to answer a questionnaire about the late diagnosis, economic status (income) and the knowledge of TB. Data were analyzed using multiple linear regression analysis method (multivariate). Results:From 60 samples, there are 31 people with low economic status and 29 people with high economic status. Samples with high TB knowledge are 34 people and samples with low TB knowledge are 26 people. There are 38 people with late diagnosis and 22 people do not experience the late diagnosis. Economic status (income) has an effect on patient late diagnosis. Patients with lower incomes, on average, visit for the first time to a health facility 165.68 days slower than those with higher incomes (b: 165.68; 95% CI -33.21 s / d 364.56, p = 0.101) .Patients knowledge about TB also has an effect on patient late diagnosis. Patients with a low level of TB knowledge, on average, visit for the first time to a health facility 128.84 days slower than patients with high levels of TB knowledge (b: 128.84; 95% CI -71.73 s / d 329.40, p = 0.204). Conclusions:There is a relationship between economic status and level of knowledge of TB with patients delay, but the results were not statistically significant. Keywords: economic status, level of knowledge of TB, the patient delays
Hubungan Diabetes mellitus dengan Hasil Uji Konversi BTA Sputum setelah Pemberian Terapi Tuberkulosis Tahap Inisiasi Avamira Rosita Pranoto; Yusup Subagio Sutanto; Sri Haryati
Nexus Kedokteran Klinik Vol 3, No 1 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Background: Pulmonary tuberculosis (TB) is a chronic infection of lung caused by Mycobacterium tuberculosis. Tuberculosis treatment often gets failure in result because of lack of care in co-morbid disease such as Diabetes mellitus (DM), which can disturb TB patient immunity. The objective of this study was to determine the relation of Diabetes mellitus and result of conversion test of sputum with alcohol-acid resistant bacillus after initiation phase of tuberculosis medication. Methods: This was an observational analytic survey with retrospective cohort study. Using consecutive sampling method, this study took 124 patients from RSUD Dr. Moewardi and BBKPM (Balai Besar Kesehatan Paru Masyarakat) Surakarta, who divided into 2 groups based on the DM status of newly diagnosed pulmonary TB patients. Control group consisted of 86 newly diagnosed pulmonary TB patients without DM; exposure group consisted of 38 newly diagnosed pulmonary TB patients with DM. Patients from both groups were given category-1 tuberculosis treatment during 2 months of initiation phase therapy, then the BTA conversion status of patients was observed. Data collected through the medical record and concurrent data of pulmonary TB patients. Data was analyzed by SPSS using Chi Square test. Probability (p) is < 0.05 with 95% confident interval. Results: There were 14 patients from the control group who failed to undergo conversion after 2 months of initiation phase therapy, whereas from the exposure group, there were 17 patients who got failure in result. Data analysis using Chi Square with significance level p < 0.05 was obtained p = 0.001 and Relative Risk (RR) = 0.66. Conclusions: DM seems to have a negative impact on the outcome of tuberculosis treatment. Pulmonary tuberculosis patients with DM as comorbid disease has probability 0.66 times lower than those without DM to get positive result from BTA sputum conversion test. Screening for DM and subsequent blood glucose control may improve the outcome of tuberculosis treatment. Keywords: Diabetes mellitus, tuberculosis medication, result of conversion test of sputum
Co-Authors . Reviono Avamira Rosita Pranoto Caesaria Sarah Selleca Sri Haryati