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All Journal Nexus Kedokteran Komunitas Paediatrica Indonesiana
Annang Giri Moelyo
Sebelas Maret University
Health Professions Medicine & Pharmacology

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Perbedaan Usia Menarche Siswa SMP Ditinjau dari Etnis Jawa, Tionghoa dan Arab di Surakarta Isna Noor Rakhmawati; Annang Giri Moelyo; Suci Murti Karini
Nexus Kedokteran Komunitas Vol 2, No 3 (2013): Nexus Kedokteran Komunitas
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.115 KB)

Abstract

Background :Menarche is the first menstrual period in woman reproduction cycle. In many studies, race and ethnicity has been shown to contribute to the age of menarche. The objective of thisstudy is to identify the difference of menarches agein junior high school girls among Javanese, Chinese and Arabian ethnic in Surakarta. Method :This wasa cross sectional study. Two hundred and thirty healthy Javanese, Chinese and Arabian students from 8th grade of 3 junior high schools in Surakarta were fulfilledthe restriction criteria. Age of menarche and ethnicity of the students were collected through a questionnaire. The difference of menarches ageamong those three ethnics were analyzed by Kruskal Wallis in SPSS 17.0 for Windows. Result :Of 230 subjects, 151 (65.65%) students were Javanese, 42 (18.26%) students were Chinese and 37 (16.09%) students were Arabian. Two hundred and fourteen (93.04%) students had recently experienced menarche. The mean age of menarche was 11.9 (SD 0.85) years old and the youngest age of menarche was 9.9 years old. The mean age of menarche in Javanese was 12 years old, in Chinese was 11.8 years old and in Arabian was 11.9 years old. Kruskal Wallis test revealed no significant difference found in the age of menarche among Javanese, Chinese and Arabian (p = 0.567). Conclusion :There is no difference of menarches age in junior high school girls among Javanese, Chinese and Arabian ethnic in Surakarta. Keyword :Ethnic,Menarches Age
Levothyroxine use and thyroid gland volumes in children with autoimmune thyroiditis: a systematic review and meta-analysis Annang Giri Moelyo; Indah Suci Widyahening; Bambang Tridjaja
Paediatrica Indonesiana Vol 59 No 4 (2019): July 2019
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (764.737 KB) | DOI: 10.14238/pi59.4.2019.202-10

Abstract

Background Autoimmune thyroiditis may manifest as overt hypothyroidism, subclinical hypothyroidism, euthyroidism, or hyperthyroidism in children. Although there is no consensus on treating euthyroidism and autoimmune thyroiditis in children, some studies have demonstrated the efficacy of levothyroxine in reducing thyroid volume, improving thyroid function, and stabilizing the immunological process. Objective To determine the effect of levothyroxine on thyroid gland volume changes, thyroid function, and thyroid antibodies in euthyroid children with autoimmune thyroiditis. Methods We performed a literature search of electronic databases (the Cochrane Library, MEDLINE, EBSCO, ProQuest, clinicaltrials.gov, and other sources, as well as a non-electronic search (searching journals and conference proceedings by hand) to identify studies of euthyroid children with autoimmune thyroiditis published by August 2018. Only English-language articles were included in the search (electronic and non-electronic). Randomized controlled trials that compared levothyroxine with a control (placebo or no treatment) in euthyroid children with autoimmune thyroiditis were selected. The outcome measures were thyroid volume changes, thyroid function, and thyroid antibody levels in euthyroid children with autoimmune thyroiditis. Two authors independently extracted the data, assessed the risk of bias, and analyzed the pooled data from the included studies using a random effects model. The same authors performed a sensitivity analysis. Results We identified 57 studies. Of these, three studies, involving 97 subjects (51 subjects in an intervention group and 46 subjects in the control group) were selected for inclusion in a systematic review/meta-analysis. The meta-analysis revealed a significant difference in mean thyroid volume changes between the two groups (-1.10 SDs; 95%CI -1.56 to -0.64; P<0.0001; I2=6%). The mean difference in the thyroid-stimulating hormone (TSH) change of the two groups was -1.82 mU/L (95%CI -3.52 to -0.11; I2=87%; P=0.04). The standardized mean difference in free thyroxine (fT4) change of the two groups was 0.82 pmol/L (95%CI -1.14 to 2.78; I2=89%; P=0.41). Conclusion In euthyroid children with autoimmune thyroiditis, levothyroxine treatment reduces the thyroid volume better. The TSH level change in the intervention group is better than those in the control group. Levothyroxine treatment did not significantly improve free T4.
Knee height and knee height/height ratio of healthy schoolchildren Annang Giri Moelyo; Andre Christiawan Susanto; Bella Monika Rajagukguk; Jonathan Billy Christian Tjiayadi
Paediatrica Indonesiana Vol 60 No 5 (2020): September 2020
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi60.5.2020.233-8

Abstract

Background Knee height (KH) is rarely used to estimate stature in children, although its measurement might have benefit because not influenced by some musculoskeletal disorder in spinal region. Knee height and knee height/height ratio are typical in children due to different in pubertal timing of each child. Objective To derive a formula to estimate body height using knee height and to analyze the patterns of knee height and knee height/height ratio of healthy schoolchildren. Methods This cross-sectional study involved healthy children in one elementary school and one junior high school in Surakarta, Central Java. Demographic data were collected (sex, age, and ethnicity). All anthropometric measurements (height, weight, sitting height, and knee height) were taken three times, and their means were calculated. Linear regression analysis was used to compare height from knee height and sitting height. Non-parametric analysis through locally weighted scatterplot smoothing (LOWESS) was used to analyze the growth patterns of knee height, knee height/height ratio, and sitting height/height ratio. Results There were 633 children (328 boys and 305 girls) in this study. The formulas for the estimation of height were as follows: for boys, 2.40 × KH (cm) + 1.36 × age (years) + 20.31; and for girls, 2.48 × KH (cm) + 1.15 × age (years) + 19.58 (adjusted R2=0.97). Knee height increased earlier than sitting height in both boys and girls during childhood to adolescent period. Boys had a longer period of knee height increment than girls. Conclusion Knee height may be a useful alternative to estimate height in children. Knee height increases faster than height and sitting height in both boys and girls.
Using the National Indonesian Growth Chart to assess short stature and obesity in urban schoolchildren in Surakarta, Indonesia: comparisons to the WHO 2007 and CDC 2000 Growth Charts Annang Giri Moelyo; Dewinda Candrarukmi; Ulfa Puspita Rachma
Paediatrica Indonesiana Vol 62 No 3 (2022): May 2022
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi62.3.2022.180-5

Abstract

Background The National Indonesian Growth Chart (NIGC) is a new growth chart based on Indonesian population data. To date, the CDC 2000 or WHO 2007 charts have been widely used in Indonesia to assess the growth of 5-to-18-year-old children. Use of these reference charts may lead to inaccurate conclusions about children’s nutritional status, particularly when diagnosing short stature or obesity. Objective To compare assessments of short stature and obesity in Indonesian urban schoolchildren and adolescents based on CDC, WHO, and NIGC reference charts. Methods Pooled anthropometric data [height, weight, and body mass index (BMI)] were collected cross-sectionally from healthy schoolchildren aged 6 to 18 years in Surakarta in 2013, 2016, 2018, and 2019. We created scatterplots for height, weight, and BMI and analyzed differences in height-for-age (HAZ) and BMI (BAZ) z-scores according to the CDC, WHO, and NIGC growth charts, then calculated differences in proportions of children identified as having short stature or obesity. Results We included 2,582 subjects; 63% were girls. Subjects’ mean age was 13.1 (SD 3.4) years. Mean differences in HAZ between the NIGC vs. CDC chart and NIGC vs. WHO chart were 1.44 (SD 0.01) and 1.39 (SD 0.00), respectively. Mean differences in BAZ between the NIGC vs. CDC chart and NIGC vs. WHO chart were 0.18 (SD 0.01) and 0.06 (SD 0.01), respectively. The prevalence of short stature was 9.91%, 11.62%, and 0.39% according to the WHO, CDC, and NIGC charts, respectively. The prevalence of obesity was 10.15%, 5.07%, and 11.77% according to the WHO, CDC, and NIGC charts, respectively. The prevalence of obesity according to the WHO, CDC, and NIGC was 7.44%, 2.95%, and 10.08%, respectively in girls and 14.76%, 8.69%, and 14.66%, respectively in boys. Conclusion The use of the NIGC resulted in a lower prevalence of short stature compared to the CDC or WHO charts. Compared to the WHO charts, the NIGC gave a similar prevalence of obesity overall and in boys, but a higher prevalence of obesity in girls. Compared to the CDC charts, the NIGC gave a higher prevalence of obesity both in boys and girls.
Co-Authors Andre Christiawan Susanto Bambang Tridjaja Bella Monika Rajagukguk Dewinda Candrarukmi Indah S. Widyahening Isna Noor Rakhmawati Jonathan Billy Christian Tjiayadi Suci Murti Karini Ulfa Puspita Rachma