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The Difference of FEV1/FVC Ratio Between Junior High School Students Living in Highland and Lowland Fajar Shodiq Irsyad Fauzi; Sinu Andhi Jusup; Martini .
Nexus Biomedika Vol 4, No 2 (2015): Nexus Biomedika
Publisher : Nexus Biomedika

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Abstract

Background: Geographically, highland is a place that has an altitude more than 500 meters above sea level. Highland has some environmental characteristic differences, thus people need an adaptation process that affects their multiple organ system. One of the systems affected is respiration system. FVC (forced vital capacity) is the total volume of air that can be forcibly exhaled in one breath. FEV1 (forced expiratory volume 1st) is the volume of air that can be exhaled in the first forced expiration. FEV1/FVC ratio is one of the lung function parameters that can describe condition of the airway. This research aimed to analyze the difference of FEV1/FVC ratio between junior high school students living in highland and lowland. Method: This research was a cross-sectional observational analytic. Samples of this research were 9th grade students of Junior High School (SMP) Amal Mulya Tawangmangu, Karanganyar and Junior High School (SMP) Negeri 2 Kretek, Bantul. The data were collected by using non-random purposive quota sampling with inclusion and exclusion criteria that had been specified. FEV1/FVC ratio data were measured by Minato Autospiro AS300 Spirometer, while the Respiratory rate and the chest circumference index were collected as supporting data. The data were analysis with the Kolmogorov-Smirnov test, the Mann-Whitney test and the independent t-test. Result: The Kolmogorov-Smirnov test showed that the FEV1/FVC ratio were not normally distributed. Mean of FEV1/FVC ratio of junior high school students living in highland was 98.522.15 whereas mean of its living in lowland was 97.653.30. The result of the Mann-Whitney comparative test showed p = 0.959 (p>0.05). Conclusion: There is no significant difference of FEV1/FVC ratio between junior high school students living in highland and lowland. Keywords: FEV1/FVC ratio, highland, lowland, lung function, spirometer
Efek Hepatoprotektor Ekstrak Daun Dandang Gendis (Clinacanthus nutans) terhadap Kadar SGPT Tikus Putih (Rattus novergicus) yang Diinduksi Parasetamol Devi Purnamasari Sasongko; Jarot Subandono; Martini .
Nexus Kedokteran Translasional Vol 1, No 2 (2012): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Paracetamol was a safe drug, but would cause oxidative stress if taken too much.. Dandang gendis leaves contained a flavonoid antioxidant. This research intended to prove the antioxidant effect of dandang gendis leaves that could prevent liver cell damage of white rat induced by paracetamol. Methods: This research was an experimental laboratoric with post test only control group design. This research had taken place at Parasitology and Micology Faculty of Medicine Sebelas Maret University Surakarta. The sample was 32 Wistar white rats. The dependent variable was the SGPT level of white rats and the independent variable was the dandang gendis leaves extract. The white rats were divided into 4 groups: negative control group (KK0), positive control group (KK1), first threated group (KP1), and second threated group (KP2). KP1 had been given 30 mg/200 gr BB dose and KP2 had been given 60 mg/200 gr BB dose for 14 days. At 11th 13th days, the white rats from KK1, KP1, and KP2 had been given 291.6 mg/200 gr BB dose of paracetamol. At 14th day, rats blood had been taken from orbitalis sinus. The damage of the liver cell had been measured with SGPT laboratory test. The data had been analyzed with one way ANOVA test then with post hoc test (? = 0.05). Results: The highest rate of SGPT levels was KK1, following KP1, KP2, and the lowest was KK0. Oneway ANOVA test resuls showed a significant difference among the four groups with p = 0.000. Post hoc test results showed a significant difference between KK0 KK1 (p = 0.003) and KK0 KP2 (p = 0.019) whereas between KK0 KP1 (p = 0.204), KK1 KP1 (p = 0.885), KK1 KP2 (p = 0.077), and KP1 KP2 (p = 0.932) had no significant difference. Conclusion: Giving dandang gendis leaves extract was not significant to raise the SGPT level of white rat induced by paracetamol. Raising dandang gendis leaves extract doses was not significant to raise its hepatoprotector effect. Keywords: dandang gendis leaf, SGPT, white rat, hepatoprotector, paracetamol
A Syntactic Analysis of a Child Language Development: A case study of Alya’s language development Martini .
Komposisi: Jurnal Pendidikan Bahasa, Sastra, dan Seni Vol 12, No 2 (2011)
Publisher : Fakultas Bahasa dan Seni UNP

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.411 KB) | DOI: 10.24036/komposisi.v12i2.3918

Abstract

Tujuan dari riset longitudinal ini adalah untuk mengetahui bagaimana seorang anak kecil menggunakan bahasa dalam kegiatan sehari-hari. Subjek dari riset ini adalah seorang anak perempuan dengan bahasa utamanya adalah Bahasa Indonesia. Data yang digunakan merupakan data autentik melalui rekaman dengan menggunakan ‘tape recorder’. Data dianalisis berdasarkan aspek-aspek sintaksis, panjang kalimat dan struktur kalimat dari ucapan yang disampaikan. Dalam riset ini ‘Mean Length Utterance’ (MLU) dari ‘Brown's Stages of Development’ di gunakan untuk mengetahui tingkat (level) dari perkembangan bahasanya. Kata kunci: analisis sintaksis, perkembangan bahasa, pemerolehan bahasa