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PENINGKATAN KEINGINTAHUAN MASYARAKAT MENGENAI PENGGUNAAN OBAT YANG BAIK DAN BENAR Sara Nurmala; Rini Ambarwati; Emy Oktaviani
Dharmakarya Vol 8, No 2 (2019): Juni 2019
Publisher : Universitas Padjadjaran

Keinginan masyarakat untuk mengetahui cara penggunaan obat yang baik dan benar saat ini harus ditingkatkan, hal ini sejalan dengan keberhasilan terapi yang nanti akan dijalani ketika mereka menerima obat. Masyarakat ketika menerima obat di apotik atau rumah sakit mereka cenderung tidak ingin menggali informasi lebih mengenai obat yang mereka terima, mereka hanya mendapatkan informasi satu arah dari apoteker yang memberikan obat. Kegiatan Pengabdian Masyarakat ini bertujuan untuk meningkatkan keingintahuan masyarakat terhadap informasi obat yang diterima sehingga penggunaan obat tersebut dapat optimal karena digunakan dengan baik dan benar. Pengabdian ini dilakukan di Puskesmas Babakan Madang, terhadap pasien yang nantinya akan menerima obat. Metode yang dilakukan adalah melakukan penyuluhan mengenai pentingnya mengenal obat yang akan mereka minum nanti, sebelum dilakukan penyuluhan, dilakukan pre test terlebih dahulu untuk menilai seberapa besar keingintahuan masyarakat terhadap penggunaan obat yang baik dan benar. Setelah penyuluhan diberikan dilakukan post test dengan soal yang sama. Hasil dari kegiatan ini adalah terdapat peningkatan pengetahuan pada 79% Pasien. Diharapkan dengan adanya peningkatan keingintahuan masyarakat mengenai penggunaan obat yang baik dan benar, dapat membantu mengurangi kasus penggunaan obat yang tidak benar dan terapi obat yang salah, sehingga kesehatan masyarakat dapat meningkat. Dalam kegiatan ini juga dilakukan pemeriksaan kesehatan gratis meliputi pemeriksaan tekanan darah dan kadar gula darah.

FORMULASI DAN UJI STABILITAS FISIK ESSENCE MASKER SHEET DARI EKSTRAK KULIT BUAH DELIMA (Punica granatum L.) Rini Ambarwati; Wulan Anggraeni; Eka Herlina
Pharmacoscript Vol. 5 No. 1 (2022): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v5i1.846

Essence merupakan cairan berbahan dasar air yang mengandung ekstrak tumbuh-tumbuhan, biasanya diaplikasikan dengan selembar kertas khusus. Kulit buah delima merupakan tumbuhan yang mengandung antioksidan yang tinggi yang dapat dimanfaatkan sebagai produk perawatan kulit. Tujuan penelitian ini yaitu untuk melakukan formulasi dan uji stabilitas fisik essence dengan metode pengeringan freeze drying dan diuji stabilitasnya menggunakan metode cycling test dan suhu kamar terlindung sinar matahari maupun terpapar sinar matahari. Sediaan dibuat sebanyak 3 formula, ekstrak kulit buah delima yang digunakan yaitu 0,75% dan HPMC yang digunakan adalah 0,5% (F1), 0,75% (F2) dan 1% (F3). Evaluasi yang dilakukan meliputi uji organoleptik (warna, aroma dan tekstur), uji homogenitas, uji derajat keasaman (pH) dan uji viskositas. Hasil penelitian menunjukkan bahwa formula 1 merupakan formula terbaik dengan nilai pH 4,77, tampilan sediaan yang homogen, nilai viskositas 445 cps, dan paling stabil disimpan dalam penyimpanan suhu kamar yang terlindung sinar matahari.

ALUMINIUM ANALYSIS IN EYE SHADOW USING ATOMIC ABSORPTION SPECTROPHOTOMETER Rini Ambarwati
Journal of Science Innovare Vol 2, No 01 (2019): Journal of Science Innovare, February 2019
Publisher : Universitas Pakuan

Industry is a human endeavor so that goods obtained from nature can be utilized as products that have a sale value and have a profitable profit in economic terms. Material from nature has chemicals that can be used for certain purposes, such as food, fuel, fuel, fertilizer, cosmetics, etc. so that human life becomes more comfortable. A chemical industry must pay attention to environmental sustainability and is expected to process materials that are safe for the environment, as well as products produced that are environmentally friendly. In the modern cosmetics industry, eyeshadow added pearly substances that have a shiny and radiant effect, in accordance with the current trend. Pearls derived from nature are Guanine, which comes from marine fish scales, are transparent and shiny crystals like pearls. Because Guanine is difficult to obtain, the producers replace it by adding synthetic pearls, including Aluminum metal powder. Aluminum is a metal used for basic materials of household appliances, but is contained in eyeshadow which functions as a pearling agent. Research on aluminum in eye shadow cosmetics has been carried out on the market. Quantitative analysis was carried out with Atomic Absorption Spectrophotometer, the results obtained showed the presence of Aluminum with the results of all eyeshadow used as samples containing Aluminum, but the level was still below the permissible level of 10%. Aluminum content contained in the eyeshadow used as a sample is between 0.35 mg / gram-16.952 mg/gram or 0.35% -1.69%. The smallest one is in the Gold E color eyeshadow brand and the highest one in the Gold B brand eyeshadow

Formulasi Transfersom Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius. R) dengan Variasi Konsentrasi Fosfolipid dan Tween 80 Sebagai Pembentuk Vesikel Rini Ambarwati; Yulianita Yulianita
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 3, No 2 (2022): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v3i2.7630

ABSTRAKPandan wangi merupakan tanaman yang sering dimanfaatkan daunnya sebagai bahan tambahan makanan, umumnya sebagai bahan pewarna hijau dan pemberi aroma. Ekstrak daun pandan wangi mengandung senyawa flavonoid yang memiliki aktivitas sebagai agen Depigmentasi. Untuk meningkatkan efektivitas dari ekstrak daun pandan wangi maka akan dibuat nanopartikel. Salah satu teknologi nanopartikel adalah transfersom. Penelitian ini bertujuan untuk menentukan formula yang paling baik dan stabil dari transfersom yang mengandung ekstrak daun pandan wangi dengan melakukan karakterisasi transfersom berdasarkan variasi konsentrasi dari fosfolipid dan tween 80. Transfersom dibuat dalam 3 formula yaitu Formula 1 (F1) dengan perbandingan fofolipid:surfaktan (90:10), F2 (85:15),dan F3 (80:20). Karakterisasi transfersom yang dilakukan meliputi distribusi ukuran partikel, zeta potensial, efisiensi penjerapan, indeks deformabilitas, dan morfologi vesikel. Hasil penelitian menunjukan bahwa formula transfersom terbaik adalah F3 (80:20), dengan rata-rata ukuran partikel 437,77 ±2,25nm, nilai rata-rata PDI (0,393±0,034), Efisiensi Penjerapan (74,172%), zeta potensial (1,35 mV±0,27), deformabilitas (12,646) dan morfologi vesikelnya berbentuk sfheris sesuai kriteria vesikel yang diharapkan. Kata kunci : Daun Pandan Wangi; Transfersom; Nanopartikel; Fospolipid.ABSTRACTPandan is a plant whose leaves are often used as food additives, generally as a green coloring agent and flavoring agent. Pandan leaf extract contains flavonoid compounds which have activity as depigmentation agents. To increase the effectiveness of the fragrant pandan leaf extract, nanoparticles will be made where the particle size will be smaller so that it can improve the delivery quality of drug compounds for the better. One of the nanoparticle technologies is transfersome. This study aimed to determine the best and most stable formula of transfersomes containing pandan leaf extract by characterizing transfersomes based on variations in the concentration of phospholipids and tween 80. Transfersomes were made in 3 formulas, namely Formula 1 (F1) with a ratio of phospholipids: :10), F2 (85:15), and F3 (80:20). The transfersome characterizations included particle size distribution, zeta potential, adsorption efficiency, deformability index, and vesicle morphology. The results showed that the best transfersome formula was F3 (80:20), with an average particle size of 437.77 ±2.25nm, an average PDI value (0.393±0.034), Adsorption Efficiency (74.172%), zeta potential ( 1.35 mV±0.27), deformability (12.646) and the morphology of the vesicles was spherical in shape according to the expected vesicle criteria.Keywords : Pandan Wangi Leaves; Transfersome; Nanoparticle; Phospoliphid.

Physical Evaluation of Transfersome that Contains Pandan Leaves Extract (Pandanus amaryllifolius R.) Rini Ambarwati; Yulianita Yulianita
Journal of Tropical Pharmacy and Chemistry Vol. 5 No. 4 (2021): Journal of Tropical Pharmacy and Chemistry
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v5i4.307

Pandan leaves have been researched and have effectiveness in the treatment of burns. The process of healing burns takes a long time and cause a hard tissue because it loses its elasticity, making it difficult to penetrate. In this study, pandanus leaves were formulated into the nanovesicle carrier system, namely trasfersom. Transfersomes have the ability to deform, namely the ability to reduce the particle size 5-10 times from the original size when passing through the gaps between cells so that transfersom can increase the penetration of active substances. The three formulas used are based on the ratio of concentrations of trasfersome vesicles, namely phospholipids and span 80. Formula 1 is (90:10), Formula 2 (85:15) and Formula 3 (80:20). The best formula is determined based on transfersom characterization, including particle size and PDI (solidispersity index), zeta potential, entrapment efficiency, deformability, and TEM particle morphology. The results showed that Formula 3 (80:20) is the most stable formula with an average particle size of 730.1 ± 4.9 nm, PDI value <0.7, zeta potential - 9.94 ± 1.02 mV, efficiency absorption 80.23%, and the deformability value 6.225.

ALUMINIUM ANALYSIS IN EYE SHADOW USING ATOMIC ABSORPTION SPECTROPHOTOMETER Rini Ambarwati
Journal of Science Innovare Vol 2, No 1 (2019): Journal of Science Innovare, Volume 02 Number 01 2019
Publisher : Universitas Pakuan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33751/jsi.v2i01.1521

Industry is a human endeavor so that goods obtained from nature can be utilized as products that have a sale value and have a profitable profit in economic terms. Material from nature has chemicals that can be used for certain purposes, such as food, fuel, fuel, fertilizer, cosmetics, etc. so that human life becomes more comfortable. A chemical industry must pay attention to environmental sustainability and is expected to process materials that are safe for the environment, as well as products produced that are environmentally friendly. In the modern cosmetics industry, eyeshadow added pearly substances that have a shiny and radiant effect, in accordance with the current trend. Pearls derived from nature are Guanine, which comes from marine fish scales, are transparent and shiny crystals like pearls. Because Guanine is difficult to obtain, the producers replace it by adding synthetic pearls, including Aluminum metal powder. Aluminum is a metal used for basic materials of household appliances, but is contained in eyeshadow which functions as a pearling agent. Research on aluminum in eye shadow cosmetics has been carried out on the market. Quantitative analysis was carried out with Atomic Absorption Spectrophotometer, the results obtained showed the presence of Aluminum with the results of all eyeshadow used as samples containing Aluminum, but the level was still below the permissible level of 10%. Aluminum content contained in the eyeshadow used as a sample is between 0.35 mg / gram-16.952 mg/gram or 0.35% -1.69%. The smallest one is in the Gold E color eyeshadow brand and the highest one in the Gold B brand eyeshadow

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