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All Journal MEDIA MEDIKA INDONESIANA Jurnal Kedokteran Diponegoro Medical Journal of Indonesia Risenologi Diponegoro International Medical Journal (DIMJ)
Amin Husni
Department Of Neurology, Faculty Of Medicine, Universitas Diponegoro Semarang, Indonesia
Chemistry Education Engineering Health Professions Mathematics Medicine & Pharmacology Neuroscience Social Sciences

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Elementary knowledge about epilepsy among the patients, their family, and common people Husni, Amin
Medical Journal of Indonesia Vol 12, No 1 (2003): January-March
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (303.74 KB) | DOI: 10.13181/mji.v12i1.87

Abstract

It is assumed that health education has been done and health information has been given through health service institutions and mass media, but it seems that the patients as well as common people have insufficient knowledge about epilepsy. Interviews had been carried out upon 127 epilepsy patients in out patient clinic Dr. Kariadi Hospital Semarang, 95 patients’ family, and 95 common people to explore their knowledge on the main disturbed organ, etiology, symptoms and signs, and trigger factors of repeating seizure in epilepsy.  The respondents’ answers were recorded verbatim, and analyzed by matching to the right answers according to references. Bad and insufficient knowledge on the main organ disturbed in epilepsy, etiology, symptoms and signs, and trigger factors for repeated seizure was founded among the epilepsy patients, their family, and common people. There were no significant differences of the level of knowledge among the three groups of respondents. The patients’ knowledge was the worst, compared to the others. The level of education of the respondents did not influence their level of knowledge. In conclusion, this study reflects an insufficient communication between doctors and the patients in the health service institution, and an insufficient public health education about epilepsy received by the patients’ family and common people. (Med J Indones 2003; 12: 29-39) Keywords: epilepsy, knowledge, patients, common people
Pengaruh Latihan Fisik dan Intervensi Kognitif Anagrams Untuk Memperbaiki Fungsi Kognitif Lansia: Literature Review Antonius Ngadiran; Amin Husni; Dian Ratna Sawitri
Risenologi Vol. 6 No. 1a (2021): Seminar Nasional Keperawatan-STIKEP PPNI Jawa Barat
Publisher : Kelompok Peneliti Muda Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47028/j.risenologi.2021.61a.217

Abstract

This literature review study is motivated by psychological problems that often arise in the elderly, one of which is a decline in cognitive function.  Cognitive function declines with age, especially the elderly whose physical activity is limited. Cognitive functions include: executive function, visuospatial, naming, memory, attention, language, abstraction, remembering and orientation. This literature is intended to theoretically analyze the effect of physical exercise and cognitive intervention on improving cognitive function in the elderly. The literature review method was carried out on seven articles obtained from a number of Google Scholar and PubMed databases. The keywords for the article search were “Fysical Execution, Cognitive Training, Cognitive Function, Elderly”. The criteria articles used in English and Indonesian, published from 2010 to 2021. The results of this study showed a significant value, namely from the seven articles showing a value (p < 0.05), which means that there is an effect of physical exercise and cognitive intervention on improving cognitive function in elderly. Physical exercise and cognitive intervention are therapies that are believed to increase cognitive function scores in the elderly. The results of this study are expected to be applied by health workers to prevent cognitive decline in the elderly.
Pemberian Fenitoin Oral dan Timbulnya Hiperplasia Ginggiva pada Pasien Epilepsi Tranggono Yudo Utomo; Amin Husni; Farichah Hanum
MEDIA MEDIKA INDONESIANA 2011:MMI Volume 45 Issue 3 Year 2011
Publisher : MEDIA MEDIKA INDONESIANA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (85.222 KB)

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ABSTRACTPhenytoin oral treatment and the development of ginggival hyperplasia in epileptic patientsBackground: Phenytoin is commonly used as a first line drug therapy for epilepsy because of its potency and low cost. Dosage and duration of oral phenytoin administration have been considered as important factors in the development of ginggival hyperplasia.Objective: To investigate whether dosage and duration of oral phenytoin usage were risk factors of ginggival hyperplasia in epileptic patients.Method: Twenty epileptic patiens with phenytoin monotherapy who developed ginggival hyperplasia, and 20 epileptic patients with phenytoin monotherapy without ginggival hyperplasia as a control group were studied. The history of illness, physical examination, fasting and post prandial blood glucose level, funduscopy, oral hygiene, index of hyperplasia scoring from Saymor were taken. Blood sample 3-5 cc were also taken to examine the level of phenytoin. Oral dose, serum dose and duration of administration were noted. Odd ratio was calculated by multiple regression statistic (95% confidence interval).Result: High dose of oral phenytoin was a significant risk factor of ginggival hyperplasia, (p<0.05), while duration of administration >6 months was not a risk factor (p=0.522). Adjusted by duration of oral phenytoin usage, high dose of oral phenytoin usage was still a significant risk factor for gingival hyperplasia, OR=29.14 (95%CI 3.8-291.9).Conclusion: High dose of phenytoin was a significant risk factor for ginggival hyperplasia.Keywords: Dosage and duration of phenytoin administration, ginggival hyperplasiaABSTRAKLatar belakang: Fenitoin sering digunakan sebagai lini pertama pengobatan epilepsi karena potensial dan ekonomis. Dosis dan lama pemberian fenitoin, dianggap sebagai faktor yang berperan dalam timbulnya hiperplasia ginggiva. Tujuan penelitian ini mengetahui apakah dosis fenitoin yang tinggi dan durasi pemberian fenitoin yang panjang merupakan faktor risiko terhadap timbulnya hiperplasia ginggiva pada penderita epilepsi.Metode: Dua puluh pasien epilepsi dengan monoterapi fenitoin yang mengalami hiperplasia ginggiva dan dua puluh pasien epilepsi dengan monoterapi fenitoin yang tidak hiperplasia ginggiva diambil sebagai studi kasus kontrol. Dilakukan anamnesa, pemeriksaan fisik, gula darah puasa dan postprandial, funduskopi, higine mulut, skoring hiperplasia Indek Saymor, pengambilan sampel darah serum fenitoin 3-5cc. Selanjutnya mendata dosis oral, dosis serum dan lama pemberian. Rasio odds (95% interval kepercayaan) dihitung dengan statistik multiple regresi.Hasil: Dosis tinggi fenitoin merupakan faktor risiko yang signifikan terhadap risiko hiperplasia ginggiva (p<0,05), sementara lama pemberian obat >6 bulan tidak terbukti sebagai faktor risiko (p=0,522). Bila dikendalikan oleh faktor durasi, maka besar dosis fenitoin oral tetap merupakan faktor risiko hiperplasia ginggiva yang signifikan OR=29,14 (95%CI, 38-291,9) sedang lama pemberian fenitoin tetap bukan merupakan faktor risiko yang signifikan.Simpulan: Dosis tinggi fenitoin merupakan faktor risiko yang signifikan terhadap hiperplasia ginggiva.
OSTEOPENIA IN MALE AND FEMALE PATIENTS USING CARBAMAZEPIN AND VALPROIC ACID COMBINATION THERAPY: Analysis of Prevalence and Its Relationship with Epilepsy Characteristics Krisninda Anggonowati; Endang Kustiowati; M.I. Widiastuti; Amin Husni; Aris Catur Bintoro; Rahmi Ardhini
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 11, No 2 (2022): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v11i2.32744

Abstract

ABSTRACT Background : Epilepsy is a chronic condition with unprovoked seizures. One of the changes affected by anti-epileptic drugs is a decrease in bone density. Gender and sex hormones have implications on bone density.Objective : To determine the prevalence difference osteopenia between male and female, and relationship with clinical characteristics epilepsy patients taking a combination of carbamazepine and valproic acid.Methods: A cross-sectional study with 22 epileptic patients with age range of 18-60 years taking combination of carbamazepine and valproic acid at the Neurology Department Dr. Kariadi Semarang during June to October 2021 who met the inclusion and exclusion criteria. Patient data were obtained by filling out a questionnaire. The assessment of osteopenia was carried out by examination of Bone Mineral Densitometry. Data analysis was using Chi Square test and Spearman correlation test. The result was determined to be significant if the p value <0.05.Results : There were 11 male subjects and 11 female subjects. Chi Square resulted in significant difference between male and female (p<0.05). Spearman correlation test showed a relationship between osteopenia and duration before combination therapy, for men rho 0.734 (p<0.05), women rho 0.786 (p<0.001). There was a relationship between osteopenia and the onset of epilepsy, male rho 0.603 (p<0.05), female rho 0.757 (p<0.001). There was a relationship between osteopenia and age, male rho 0.487 (p=0.129), female rho 0.780 (p<0.001). There was also a relationship between osteopenia and seizure frequency, male rho 0.457 (p<0.05), female rho 0.467 (p=0.026).Conclusion: There was a significant osteopenia prevalence difference between male and female epilepsy patients taking combination of carbamazepine and valproic acid. Moderate and strong relationship were found between osteopenia and clinical characteristics epilepsy. Keywords : Epilepsy, osteopenia, carbamazepine, valproic acid
The Relationship Between Severity of Periodontitis With the Degree of Atherosclerosis in Ischemic Stroke Patients Elisabeth Romana Tikalaka; Amin Husni; Retnaningsih -; Dodik Tugasworo; Jimmy Eko Budi Hartono; Maria Belladonna Rahmawati; Iva Puspitasari
Diponegoro International Medical Journal Vol 2, No 2 (2021): December
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v2i2.9605

Abstract

AbstractBackground : Periodontal diseases affect up to 80% of the global population. Periodontitis is a long-term inflammatory disease that affects the soft and hard tissues around the teeth. It may also play a role in the pathogenesis of atheroma formation and is associated with cerebrovascular disease. The Carotid Intima Media Thickness (CIMT) is a good marker for detecting early and progressive atherosclerosis. Several hypotheses link chronic infectious diseases, including periodontal tissue disease, to the atherosclerosis process and are risk factors for stroke.Objective : To determine the relationship between the severity of periodontitis and the degree of atherosclerosis in ischemic stroke.Methods : This is an analytic observational study with a case-control approach. Subjects were ischemic stroke patients with inclusion criteria. Analyzed the severity of periodontitis with Miller’s Mobility Index (MMI), the degree of progression of atherosclerosis assessed by measuring the CIMT using an ultrasound device or B mode to detect the presence and progression of atherosclerosis.Results : 54 subjects with a mean age were 63,43 ± 7,19 years, and the dominant sex was male. There was a significant relationship between severity of periodontitis  ( P : 0,011, OR : 3,425, CI 95% 1,332-8,807) and type of profile lipid triglyceride ( P : 0,027, OR : 6,840, CI 95% 1,242-37,676)  to Carotid intima media thickness.Conclusion :  There is an association between the severity of periodontitis and the degree of atherosclerosis. Severe periodontitis is related to the increases of CIMT, which is a marker of atherosclerosis, a risk factor for stroke.
Co-Authors Antonius Ngadiran Aris Catur Bintoro Dian Ratna Sawitri Dodik Tugasworo Elisabeth Romana Tikalaka Endang Kustiowati Farichah Hanum Iva Puspitasari Jimmy Eko Budi Hartono Krisninda Anggonowati M.I. Widiastuti Maria Belladonna Rahmawati Rahmi Ardhini Retnaningsih Retnaningsih Tranggono Yudo Utomo