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Journal : The Journal of Pure and Applied Chemistry Research

A Flavonoid Glycoside Compound Isolated from Macaranga gigantifolia Merr Leaves Gian Primahana; Akhmad Darmawan
The Journal of Pure and Applied Chemistry Research Vol 6, No 1 (2017): Edition of January - April 2017
Publisher : Chemistry Department, The University of Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (764.598 KB) | DOI: 10.21776/ub.jpacr.2017.006.01.298

Abstract

Apigenin-8-C-glycoside (1), a flavonoid glycoside compound has been isolated from the leaves of Macaranga gigantifolia Merr. Isolation and purification conducted by chromatography methods and chemical structure characterization carried out by spectroscopic methods. Cytotoxicity of Apigenin-8-C-glycoside has been tested against Murine leukemia P-388 cell lines and has moderate activity with IC50 values 55.4 μg/mL.