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All Journal Damianus Journal of Medicine Biomolecular and Health Science Journal
David Nugraha
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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POLA SENSITIVITAS ANTIBIOTIK PADA PENYAKIT MUSKULOSKELETAL DI RUMAH SAKIT ORTHOPEDI DAN TRAUMATOLOGI SURABAYA Nabila Ananda Kloping; David Nugraha; Andro Pramana Witarto; Komang Agung Irianto
Bahasa Indonesia Vol 19 No 1 (2020): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v19i1.1273

Abstract

Introduction: Indiscriminate use of antibiotics contributes to the increasing resistance of more than one type of bacterias. Research on new antibiotic therapies and agents cannot keep up with the rapid antibiotic resistance. This study aimed to describe the patterns of antibiotic sensitivity and resistance at the Orthopedic and Traumatology Hospital (RSOT) Surabaya. Methods: This was a cross-sectional descriptive study. Secondary data from medical records year 2016-2018 were retrieved from patients treated at RSOT Surabaya who received antibiotic therapy. Only those with data of antibiotic sensitivity test results were included Results: The sensitivity test results of all b-lactamase inhibitors and cephalosporin antibiotics showed a decrease in sensitivity each year with a variety of coverage patterns. The fluoroquinolone group had increased sensitivity during the observation period. Conversely, a reduction in gentamicin sensitivity was followed by an increase in the resistance. This increase in resistance was also observed in meropenem with various sensitivity patterns. Linezolid sensitivity increased, while the sensitivity of teicoplanin remained 100.00%. Conclusion: There is no particular pattern in antibiotic sensitivity and bacterial resistance in RSOT Surabaya, except for cephalosporin, which shows a rising resistance and a decrease in sensitivity each year.
Breeding Preference and Bionomics of Anopheles spp. at the Malarial Endemic Area, Runut Village, East Nusa Tenggara Province, Indonesia Gery Morsales Munthe; David Nugraha; Gabriel Pedro Mudjianto; Etik Ainun Rohmah; Arnoldina Dolfina Dua Weni; Zukhaila Salma; Lynda Rossyanti; Fitriah; Suhintam Pusarawati; Budi Utomo; ukmawati Basuki; Haruki Uemura
Biomolecular and Health Science Journal Vol. 5 No. 1 (2022): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bhsj.v5i1.35278

Abstract

Introduction: Anopheles mosquito is transmitting malaria, one of the health problems in Indonesia. Understanding Anopheles mosquito behaviour and its breeding preference is one of the crucial keys to prevent malaria transmission. This study aimed to identify the breeding place distribution and bionomics of Anopheles spp. in Runut village, Sikka district, East Nusa Tenggara. Methods: A descriptive observational study was conducted in Runut village, Waigete sub- district, in April 2018. Anopheles spp. larvae were collected in 7 suspected breeding places consisting of 2 rice fields, 3 fish ponds, and 2 puddles. Mosquitos behaviour was observed using bed-net traps located inside and outside the house from 7.15 PM to 1.15 AM after obtaining informed consent. Mosquito collection using bed-net trap were performed for 40 minutes then followed by resting mosquito collection for 10 minutes. Results: Anopheles spp. larvae were found in most of the suspected aquatic habitats, presenting different densities and together with larvae of the other mosquito species. Relatively high number of Anopheles spp. larvae was obtained from a puddle. Only one female mosquito of Anopheles spp. resting on the wall inside house was found around 00.55 – 01.05 AM and resulted in low mosquito density determination. Conclusion: Anopheles spp. larvae were harbouring in most of the aquatic habitats and one puddle contained moderately abundant larvae of Anopheles in Runut village, Sikka district, East Nusa Tenggara, Indonesia. Even only one Anopheles spp. mosquito was detected inside the house, residents in Runut village should regular use insecticide-treated bed nets and continuous observation of mosquito breeding places especially puddles to prevent malaria and other mosquito-borne diseases.
Co-Authors Andro Pramana Witarto Arnoldina Dolfina Dua Weni BUDI UTOMO Etik Ainun Rohmah Fitriah Gabriel Pedro Mudjianto Gery Morsales Munthe Haruki Uemura Komang Agung Nabila Ananda Kloping ROSSYANTI, LYNDA Suhintam Pusarawati ukmawati Basuki Zukhaila Salma