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Ikram M. Said
School of Chemical Sciences & Food Technology, Faculty of Science and Technology, UKM
Mathematics

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Tiga Senyawa Oligostilbenoid dari Kulit Batang Dipterocarpus retusus Blume (Dipterocarpaceae) Muhtadi Muhtadi; Euis Holisotan Hakim; Yana Maolana Syah; Lia Dewi Juliawaty; Sjamsul Arifin Achmad; Ikram M. Said; Jalifah Latip
Jurnal Matematika & Sains Vol 10, No 4 (2005)
Publisher : Institut Teknologi Bandung

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Abstract

Three oligostilbenoids, (-)-ε-viniferin, (-)-α-viniferin and (-)-vaticanol A, together with two derivative coumarin compounds, scopoletin and (-)-bergenin, were isolated from acetone extracts of the tree bark of Dipterocarpus retusus Blume. The chemical structure of the isolates were established based on spectroscopic data, UV, IR, 1H-NMR, 13C-NMR, and by comparison with the related compounds. (-)-ε-Viniferin, (-)-α-viniferin and (-)-vaticanol A showed cytotoxic activity against murine leukaemia P-388 cells with their IC50 values were 7,8; 17,5 and 27,0 µg/mL, respectively.
Co-Authors Euis Holisotan Hakim Jalifah Latip Lia Dewi Juliawaty Muhtadi Muhtadi Sjamsul Arifin Achmad Yana Maolana Syah