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All Journal Jurnal Farmasi Udayana Jurnal Katalisator Jurnal Kesehatan Farmasi
Tuty Taslim
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : Jurnal Kesehatan Farmasi

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Uji Efek Analgetik Ekstrak Etanol Bunga Kecombrang (Etlingera elatior. jack) Terhadap Mencit Putih Jantan (Mus musculus) Fita Selonni; Tuty Taslim
Jurnal Kesehatan Farmasi Vol 4, No 2 (2022)
Publisher : Jurusan Farmasi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (434.039 KB) | DOI: 10.36086/jpharm.v4i2.1428

Abstract

Background : Ibuprofen is a drug that is commonly used when the body experiences pain. In this study, the medicinal plant that will be tested for its analgesic effect on mice is Kecombrang flower. Methods: Kecombrang flowers were first used as ethanol extract with two different concentrations, namely 400 mg/kgBb and 800 mg/kgBb. The experimental animals used were 20 male white mice which were divided into 4 groups where each group consisted of 5 mice. Each group of mice was given a dose treatment first, then 30 minutes after that, 1.1% acetic acid solution was given via ip, after that, pay attention to the amount of writhing shown by the mice. Results: From the 2 concentrations of kecombrang flower ethanol extract given, it turned out that the 400 mg/kgBb dose group showed fewer stretches than the 800 mg/kgBb dose group, but the analgesic effect was still low compared to the control group + namely ibuprofen. Key words : Kecombrang flower, analgesic and mice
Co-Authors Fita Selonni Irene Puspa Dewi Monica T Rusvaira Khairunnisa Salim R Verawaty Verawaty