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All Journal Jurnal Anestesiologi Indonesia Nusantara Medical Science Journal Journal of Anesthesiology and Clinical Research Majalah Anestesia & Critical Care (MACC)
Andi Muhammad Takdir Musba
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health

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Journal : Nusantara Medical Science Journal

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Perbandingan Remifentanil Kontinu 0.15 Mcg/Kgbb dengan Fentanyl 3 Mcg/Kgbb pada Intubasi Endotrakeal Diukur Menggunakan Pupillometer (AlgiScan®) Fauzan Bachtiar Amin; Alamsyah A.A Husain; Andi Muhammad Takdir Musba; Muh Ramli Ahmad
Nusantara Medical Science Journal Volume 5 No. 2 Juli - Desember 2020
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v5i2.9912

Abstract

Introduction: All opioids have varying levels of sedative effects with increasing dosages, although with different strengths. Therefore, the opioid component as a sedative regiment is usually maintained at minimum dose for adequate analgesic with regard to patient comfort. Along with the progress of knowledge, parameters have been found to measure the level of analgesic and sedative. Methods: The principle of measurement is done by using the diameter of pupil and then analyzed through AlgiScan and compared to certain standards. The using of pupilometers AlgiScan in assessing the level of sedative analgesic will reduce the level of subjectivity and errors in measurement. Results: The use of Remifentanil has a faster effect of sedative as proven by lower “AlgiScan” score in the pre-intubation phase. In addition, the use of Remifentanil also provides a hemodynamic view of lower arterial pressure, both pre and post intubation condition. Conclussion: Both Remifentanil and fentanyl are able to provide analgesic with sedative and stable hemodynamics. Remifentanil is proven to be superior with better and faster effect and also faster substance elimination with lower doses.
Efektivitas Lidokain Intravena Kontinyu Perioperatif Terhadap Intensitas Nyeri Dan Total Konsumsi Opioid Pasca Bedah Dekompresi Dan Stabilisasi Posterior Vertebra Fadli Rachman; Ratnawati R; Andi Muhammad Takdir Musba
Nusantara Medical Science Journal Volume 5 No. 1 Januari - Juni 2020
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v5i1.10154

Abstract

introduction: Intravenous lidocaine had been used as multimodal analgesia strategy in treating acute postoperative pain. This study aimed to examine the effectivity of perioperative intravenous lidocaine infusion on pain intensity and total opioid requirements postoperative. Methods:  This study was  a double blind randomized control trial on ASA physical status I-II, aged 18-60, BMI 18-30 kg/m2 underwent to spine decompression and stabilisation surgery in Wahidin Sudirohusodo general hosputal, Makassar. Results:   The samples were randomly devided into lidocaine group ( n=28) received lidocaine 1,5 mg/kg before intubation, followed by 1,5 mg/kg/hour intraoperative and 1 mg/kg/hour untl 12 hour postoperative, and the control group (n=28) received placebo NaCl 0,9%. The data were analyzed with Chi-square test, independent-t test, and Mann-Whitney test, and considered significant if the p value <0,05. The study result showed that compared to the control group, the pain intensity of lidocaine group were lower in measurement time 6 (p=0,05),12 (p=0,045) and 24 (p=0,031) hour postoperative but not in 2 (p=148) and 4 (p=0,472)  hour postoperative. Total fentanyl consumption 24 hour postoperative  were lower in lidocaine group ( 418,32±146,45 vs 579,86±145,29 ; p=0,000). Conclusions:  This study concluded that administration of intravenous lidocaine infusion perioperative able to reduce pain intensity dan total opioid requirements after spine decompression and stabilisation surgery.
Co-Authors Alamsyah A.A Husain Alamsyah Ambo Ala Husain Alamsyah Irwan Alamsyah Irwan Albert Winata Andi Adil Andi Salahuddin Andi Taufik Amiruddin Ari Santri Palinrungi Fadli Rachman Fauzan Bachtiar Amin Haizah Nurdin Hisbullah Muh Ramli Ahmad Ratnawati Ratnawati R Syafri Arif Syafri Kamsul Arif Syamsul Salam Taufik Anshori Tekad Ariffianto