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All Journal Jurnal Anestesiologi Indonesia Budapest International Research in Exact Sciences (BirEx Journal) Britain International of Exact Sciences Journal (BIoEx Journal)
Eka Adhiany
Department Of Anesthesiology And Intensive Therapy, Faculty Of Medicine, Universitas Syiah Kuala, Banda Aceh
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Health Professions Mathematics Medicine & Pharmacology Physics Public Health Transportation

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Perbedaan Sedasi Midazolam dan Ketamin terhadap Base Excess Pasien dengan Ventilator Eka Adhiany; Heru Dwi Jatmiko; Uripno Budiono
JAI (Jurnal Anestesiologi Indonesia) Vol 6, No 1 (2014): Jurnal Anestesiologi Indonesia
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (479.44 KB) | DOI: 10.14710/jai.v6i1.6649

Abstract

Latar belakang: Agitasi dan kecemasan sering terjadi pada pasien-pasien Intensive Care Unit (ICU). Kejadian kecemasan berkisar di atas 70% dari pasien-pasien ICU). Ini membutuhkan pemberian obat sedasi dan analgesia. Obat sedasi yang dapat digunakan antara lain midazolam dan ketamin. Kedua obat ini memiliki perbedaan dalam efek ke pembuluh darah.Tujuan: Untuk menemukan perbedaan nilai base excess (BE) melalui analisa gas darah arteri pasien ICU yang menggunakan midazolam dibandingkan dengan ketamin sebagai sedasi.Metode: Suatu uji klinik eksperimental yang dilakukan secara acak tersamar ganda pada pasien yang menggunakan ventilator di unit rawat intensif. Pasien (n : 28) dibagi menjadi 2 kelompok, K1 yang mendapat sedasi ketamin dan K2 mendapat midazolam. Pasien diberikan sedasi selama 24 jam dengan dosis bervariasi dengan target kedalaman sedasi pasien pada Ramsay Score 4, kemudian diperiksa nilai analisis gas darah pada jam ke-0, 6, dan 24.Hasil: Hasil perbandingan sedasi midazolam dengan ketamin ini menunjukkan perbedaan bermakna pada nilai base excess yang menggunakan sedasi ketamin jam ke-0 dan jam ke-6 saja dengan nilai p=0,04 (p<0.05), sedangkan untuk jam ke-0 dan jam ke-24 didapatkan perbedaan yang tidak bermakna dimana p=0,55, dan untuk jam ke-6 dan jam ke-24 juga didapatkan perbedaan yang tidak bermakna dimana p=0,786.Simpulan: Tidak ada perbedaan yang bermakna pada hasil pemeriksaan base excess darah arteri pada pasien menggunakan ventilator dalam 24 jam yang diberikan midazolam dibandingkan dengan ketamin.
Medicines Used in Emergency Imai Indra; Eka Adhiany
Britain International of Exact Sciences (BIoEx) Journal Vol 2 No 2 (2020): Britain International of Exact Sciences Journal, May
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v2i2.227

Abstract

The aims of the study is to find the emergency medicines. The result Ine Epinephrine is a sympathomimetic, adrenergic group. Epinephrine effects can be seen in: Cardiovascular secondary hypotension, reversal epinephrine), gastrointestinal, uterine, bladder, respiratory, CNS, eye and metabolic processes. Clinical use can be seen in: Cardiovascular hypotension secondary, reversal epinephrine), gastrointestinal tract, uterus, bladder, breathing, CNS, eyes and metabolic processes. Stimulate the heart in patients with cardiac arrest and stop capillary bleeding. Ephedrine is a sympathomimetic, adrenergic class of drugs. The pharmacodynamics effect of ephedrine resembles the effect of epinephrine, the difference is that ephedrine is not a catecholamine, it is effective in oral administration, the duration of action is much longer, the central effect is stronger, but a much larger dose of epinephrine is needed, the difference being that ephedrine is not a catecholamine, it is effective in oral administration, its duration is much longer, the central effect is stronger, but a much greater dose is needed than the epinephrine dose. Like epinephrine, ephedrine acts on α, β1 and β2 receptors. The ephedrine cardiovascular effect resembles the effect of epi but lasts about 10 times longer.
Diagnosis of Pulmonary Hypertension Using Ultrasonography in the Management of Critical Patients in the Intensive Care Unit Eka Adhiany; Muhammad Iqbal
Budapest International Research in Exact Sciences (BirEx) Journal Vol 2, No 4 (2020): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v2i4.1364

Abstract

Pulmonary arterial hypertension is most often diagnosed in its advanced stages because of the nonspecific nature of early symptoms and signs. Although clinical assessment is essential when evaluating patients with suspected pulmonary arterial hypertension, echocardiography is a key screening tool in the diagnostic algorithm. Echocardiography is valuable in assessing prognosis and treatment options, monitoring the efficacy of specific therapeutic interventions, and detecting the preclinical stages of disease. In this report, we reported A 35 years old woman admitted to the emergency unit with breathing difficulty which has felt since 2 days before. she transferred from rural hospital after hospitalized for a week. The patient has history of spinal surgery due to spondylitis tuberculosis 8 months ago and has an anti-tuberculosis drug for 2 months. The vital signs show respiratory failure with blood pressure 114/70 mmHg, heart rate 118 bpm, respiratory rate 35-40 bpm and pulse saturation 80-85% with non-rebreathing mask. Physical examination shows increasing work of breathing, without rales and wheezing, liver enlargement palpated 3 fingers below right ribs the chest x ray shows cardiomegaly and right pleural effusion
Co-Authors Heru Dwi Jatmiko Imai Indra Muhammad Iqbal Uripno Budiono