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All Journal Paediatrica Indonesiana The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy
Darmawan Kartono
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Health Professions Medicine & Pharmacology

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Hepatocellular Carcinoma in an Infant due to HBV Vertical Transmission Rahmah, Nunung Ainur; Marwoto, Wirasmi; Yuwono, Vera; Krisnuhoni, Ening; Handjari, Diah Rini; Kartono, Darmawan; Muljono, David Handojo
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 10, ISSUE 1, April 2009
Publisher : The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.036 KB) | DOI: 10.24871/101200929-32

Abstract

Hepatocellular carcinoma (HCC) is one of the common tumors in the world. The incidence of HCC generally increases with age in all population but there is a tendency of decreasing incidence in the elderly and it is very rare in children. This is a case report of HCC in a 9-month-old boy, who was admitted to the hospital with palpable abdominal mass in the right upper quadrant. Imaging modality by ultrasonography could not adequately demonstrate definite findings demonstrating that the tumor was derived from liver, and the diagnosis was neuroblastoma. Intra-operatively, the tumor mass appeared to be derived from the surface of the posterior edge of the liver, so it was a pedunculated tumor. The histopathological examination revealed a pedunculatedhepatocellular carcinoma grade 3. The Victorian blue staining and immunohistochemical staining were done afterward, which showed HBsAg positive result as found in non-tumor lesion as well as inneoplastic lesion of liver tissue.Keywords: hepatocellular carcinoma, pedunculated HCC, infant HCC, occult hepatitis B virus infection
Ischiopagus Tetrapus Conjoined Twins Nartono Kadri; Harapan Parlindungan Ringoringo; Darmawan Kartono
Paediatrica Indonesiana Vol 36 No 7-8 (1996): July - August 1996
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (482.621 KB) | DOI: 10.14238/pi36.7-8.1996.169-76

Abstract

We report a case of ischiopagus tetrapus conjoined twins with one pas­sageway (cloaca type) and bom at term by spontaneously vaginal dcliveiy, with a combined birth weight of 5000 grams. There was no history of twin in the family. Dur­ing hospitalization, the conjoined twins suffered from sepsis due to ascending infection from cloacal portion, At the age of 17 days, an exploratory laparatomy and divided co­lostomy was performed. The postoperative complications were bleeding and sepsis. The bleeding could be properly handled only in 4 days after the treatment, whilst sepsis could not be overcome. Even in the 16th day after the operation, a peritonitis occurred followed by intestines prolapse from the edge of operative incision (on the 19th post­operative day) resulting in the death of the conjoined twins.
Hepatocellular Carcinoma in an Infant due to HBV Vertical Transmission Nunung Ainur Rahmah; Wirasmi Marwoto; Vera Yuwono; Ening Krisnuhoni; Diah Rini Handjari; Darmawan Kartono; David Handojo Muljono
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 10, ISSUE 1, April 2009
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/101200929-32

Abstract

Hepatocellular carcinoma (HCC) is one of the common tumors in the world. The incidence of HCC generally increases with age in all population but there is a tendency of decreasing incidence in the elderly and it is very rare in children. This is a case report of HCC in a 9-month-old boy, who was admitted to the hospital with palpable abdominal mass in the right upper quadrant. Imaging modality by ultrasonography could not adequately demonstrate definite findings demonstrating that the tumor was derived from liver, and the diagnosis was neuroblastoma. Intra-operatively, the tumor mass appeared to be derived from the surface of the posterior edge of the liver, so it was a pedunculated tumor. The histopathological examination revealed a pedunculatedhepatocellular carcinoma grade 3. The Victorian blue staining and immunohistochemical staining were done afterward, which showed HBsAg positive result as found in non-tumor lesion as well as inneoplastic lesion of liver tissue.Keywords: hepatocellular carcinoma, pedunculated HCC, infant HCC, occult hepatitis B virus infection
Co-Authors David Handojo Muljono Diah Rini Handjari Diah Rini Handjari Ening Krisnuhoni Harapan Parlindungan Ringoringo Nartono Kadri Nunung Ainur Rahmah Vera Yuwono Wirasmi Marwoto Wirasmi Marwoto