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All Journal Pharmaciana: Jurnal Kefarmasian JPS Unimus IDJP (Indonesian Journal of Pharmaceutics)
Muhaimin Muhaimin
Jambi University
Chemistry Education Environmental Science Medicine & Pharmacology Physics Social Sciences Other

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Topical anti-inflammatory effect of Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves extract Bernike Anatasya; Fathnur Sani K; Muhaimin Muhaimin
Pharmaciana Vol 11, No 3 (2021): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (395.99 KB) | DOI: 10.12928/pharmaciana.v11i3.17617

Abstract

Ekor Naga (Rhaphidophora pinnata (L.f) Schott) leaves are leaves that contain secondary metabolites which can be developed into medicine. Ekor Naga leaves have secondary metabolite compounds of flavonoids, alkaloids, triterpenoid saponins, steroids, tannins, and phenols. This metabolite compound is the basis for testing the anti-inflammatory effect of Ekor Naga leaves extract using topical methods. The purpose of this study was to determine the anti-inflammatory effect of the ethanol extract of Ekor Naga leaves by a topical method. This study used five treatment groups with five mice in each treatment. This research tested the anti-inflammatory activity of Ekor Naga leaves extract by using the combination of 2 methods; namely the method of forming airbags and the formation of artificial edema using the induction of 2% carrageenan solution with the observation parameters being the measurement of exudate volume and differentiation of the number of leukocyte cells observed under a microscope. The results showed that the Ekor Naga leaves extract had an anti-inflammatory effect. The best inflammatory effect is a concentration of 10%, followed by a concentration of 5% and 2.5%.
Formulation of Antioxidant Emulgel containing Beluntas China (Gynura pseudochina (L.) DC) Fitriani Jati Rahmania; Marline Abdassah; Muhaimin Muhaimin; Anis Yohana Chaerunisaa
Indonesian Journal of Pharmaceutics Vol 2, Issue 1, Jan - April 2020
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v2i1.26106

Abstract

Skin constantly exposed by the environmental stresses, such as pollutants, solar radiation, heat, and cold, which cause the free radicals that cause premature aging. This bad effects of free radicals can be reduced by natural antioxidants such as Beluntas china (Gynura pseudochina (L.) DC) extract. The antioxidants use of beluntas china extract for skin will be more optimal if it is applied by appropriate form, emulgel, which has stronger consistency and longer contact time than gel. The aim of this research was to formulate an antioxidant emulgel from beluntas china extract, which is effective, stable, and safe with the best gelling agent. The extract was formulated by variety types of gelling agents which were carrageenan, hydroxypropyl methylcellulose (HPMC), and carbomer 934. Then, the physical stability was evaluated, including organoleptic, homogeneity, pH, viscosity, and freeze thaw. The results showed that formulation of carbomer 934 1% 2xIC50 extract concentration give the best physical stability evaluation for 60 days storage time.Keywords: antioxidant, beluntas china extract, emulgel, free radicals, skin
The Descriptive Analysis of TPACK Components in Chemistry Learning Tools for The Electrolyte and Non-electrolyte Solutions Materials Rifanny Rizka Putri; Muhaimin Muhaimin; Sutrisno Sutrisno
JURNAL PENDIDIKAN SAINS UNIVERSITAS MUHAMMADIYAH SEMARANG Vol 9, No 2 (2021): JURNAL PENDIDIKAN SAINS UNIVERSITAS MUHAMMADIYAH SEMARANG
Publisher : Pendidikan Kimia Unimus

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26714/jps.9.2.2021.126-136

Abstract

Electrolyte and non-electrolyte solutions were chemical materials that had three levels of representation. However, during the learning process there were still many learning difficulties. One of the factors that students experience difficulty in learning was that teachers were not optimal in planning lessons. However, in the process of achieving learning objectives, it was necessary to had optimal learning planning. One of the optimal learning plans was obtained by preparing learning instruments such as lesson plans and e-LKPD which integrated TPACK. This research was a descriptive study which aims to analyzed descriptively the TPACK components in the developed chemistry learning tools. The data collection techniques in this study used document study techniques, interviews, and surveys. The data instruments used in obtaining information were questionnaires, interview guideline sheets, and previous articles. Researchers took samples by purposive sampling. The research subjects were students and teachers of class X IPA SMA in Jambi City. Based on the analysis conducted by researchers through data collection instruments, it can be concluded that this learning tool has integrated Technology, Pedagogic, and Content Knowledge components.
Co-Authors Anis Yohana Chaerunisaa Bernike Anatasya Fitriani Jati Rahmania Marline Abdassah Rifanny Rizka Putri Sani K, Fathnur Sutrisno Sutrisno