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. Kiyatno
Sebelas Maret University
Biochemistry, Genetics & Molecular Biology

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Efektifitas Olahraga Aerob Intensitas Berat Dalam Meningkatkan Kadar High Density Lipoprotein (HDL) Plasma Narwienda, Aldila Akhadiyati; Kiyatno, .; Yusuf, Sinu Andhi
Nexus Biomedika Vol 2, No 1 (2013): Nexus Biomedika
Publisher : Nexus Biomedika

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Background: The value of regular aerobic exercise in increasing HDL level of plasma has accepted widespread acceptance. In contrast, the only few studies have examined the effect of HDL-C level to exercise training. The objective of this study was to determine the most effective intensity of the aerobic exercise in increasing HDL plasma level. Method: This was an experimental laboratory study with randomized pre-test and post-test control group design. This study was conducted from April to June 2012 at Laboratory of Physiology FK UNS. Forty subjects were divided into four groups based on purposive sampling method. There were control group, mild-intensity group, moderate-intensity group and high-intensity group. The HDL level tests were taken before and after eight weeks of intervention. The results then were analyzed with one-way ANOVA test. Results: Based on one-way ANOVA test, there was significant difference among groups in the study (p = 0.002). Based on multiple comparison analyzes, (1) there was no significant difference between the raise of HDL plasma level in control group and mild-intensity group (p = 0.749), (2) there was significant difference between the raise of HDL plasma level in control group and moderate-intensity group (p = 0.044), and (3) there was significant difference between the raise of HDL plasma level in control group and high-intensity group (p = 0.002). Conclusions: High-intensity aerobic exercise was the most effective in increasing the HDL plasma level. Keywords: HDL, aerobic exercise, intensity 
Pemberian Suplemen Branched Chain Amino Acids (BCAA) untuk Mengurangi Tingkat Kelelahan pada Mahasiswa Pendidikan Dokter Universitas Sebelas Maret Abdulhamid, Muhammad; Kiyatno, .; Hikmayani, Nur Hafidha
Nexus Biomedika Vol 2, No 2 (2013): Nexus Biomedika
Publisher : Nexus Biomedika

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Background: Fatigue is a condition characterized by a decrease in work efficiency and endurance. BCAA capsule contains of three kinds of essential amino acids, those were leucine 2275 mg, isoleucine 1137.5 mg, and valine 1137.5 mg, each of which plays an important role in protein synthesis and energy system for activity. This study aimed to examine the effect of supplement administration of BCAA to reduce fatigue levels in medical students of Sebelas Maret University (UNS). Methods: This was an experimental research with pretest-posttest group design. It was conducted at Faculty of Medicine UNS on December 13th, 2012. Subjects (n=40) were randomly selected from list of current medical students at preclinical level. Subjects who had been fasting for eight hours, then, were randomly arranged into two groups: (1) control group whose fatigue levels were measured twice in resting condition at10-minute interval, and (2) treatment group whose fatigue levels were measured before and 10 minutes after BCAA administration. Fatigue referred to decreasing concentration determined by reaction time to light stimuli. Pretest-postest fatigue levels for each group were analyzed using paired sample t-tests, whereas posttest fatigue levels between the two groups were analyzed using independent sample t-test. Data analysis were performed using SPSS 17.0 for Windows. Results: Mean fatigue levels of control group at first and second measurement, each, were 270.1±15.3 and 255.5±10.9 millisecond. While mean fatigue levels of treatment group at pretest and after BCAA administration were 268.9 ± 14.8 and 211.7±38.8 millisecond, consecutively. Analysis of paired sample t test of  pretest-postest fatique levels in both groups, each,  showed significant difference (p = 0.001 for control group and p < 0.001 for treatment group), while analysis of independent t test of posttest fatigue levels between the two groups showed that the posttest fatigue levels between the two groups also differed significantly (p <0.001). Conclusions: BCAA administration significantly reduced fatigue levels in medical students of UNS. Fatigue levels were significantly shorter in subjects administered BCAA supplement than those of control group who did not take BCAA supplement. Keywords: BCAA suplement, fatigue
Hubungan antara Yoga dengan Siklus Menstruasi Sari, Indah Purnama; Kiyatno, .; Hanim, Diffah
Nexus Biomedika Vol 3, No 3 (2014): Nexus Biomedika
Publisher : Nexus Biomedika

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Background: Disturbed menstrual cycle often causes anxiety women. Menstruation disturbance can affect daily activities, that can decrease productivity. Nutrition and physical activities can affect regularity of menstrual cycle. Yoga is a popular physical activity recently that can influence hormone reproduction. This study aims to investigate the relationship between Yoga and menstrual cycle. Method: This research was an observational analytic research with cross sectional approach. There were 63 subjects of research that were chosen using purposive sampling of women who took Yoga course in Ganeps Surakarta. Independent variable of this research was Yoga. While dependent variable of this research was menstrual cycle. Data collected by direct interview with a list of questions to respondent were analyzed using bivariate Chi-Square, Contingency coefficient, and Odds. Result: The result of  Chi-Square test showed there was significant correlation between Yoga and menstrual cycle (p = 0.000). Coefficient of contingency test showed that 43.5% women who took Yoga course had regular menstrual cycle (C = 0.43; and p =0.000). While Odds Ratio test showed that women who took Yoga course had possibility 9.86 times to have regular menstrual cycle (OR = 9.86; CI 95% 2.87 - 34.95; and p = 0.000). Result of Research: There is significant correlation between Yoga and menstrual cycle. Keywords: Yoga, menstrual cycle 
Co-Authors Aldila Akhadiyati Narwienda Diffah Hanim Laksono Trisnantoro Muhammad Abdulhamid Nur Hafidha Hikmayani Sinu Andhi Yusuf