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All Journal Jurnal Ekonomi Syariah Teori dan Terapan Dental Journal (Majalah Kedokteran Gigi) Journal of Dentomaxillofacial Science Jurnal Layanan Masyarakat (Journal of Public Service) Indonesian Journal of Dental Medicine
Yuliati
Department Of Oral Biology, Faculty Of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
Humanities Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Environmental Science Social Sciences Other

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Journal : Indonesian Journal of Dental Medicine

 1 
Epigallocatechin gallate Mucoadhesive Gingival Patch as Potential Biomaterial to Regulate Macrophage and Lymphocyte Cells in Periodontitis: A Review Sidarningsih Sidarningsih; Indeswati Diyatri; Reinaya Tifa Pratiwi; Jihan Hijriya Nabilla; Yuliati Yuliati; Rini Devijanti Ridwan
Indonesian Journal of Dental Medicine Vol. 5 No. 1 (2022): January - June
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v5i1.2022.32-36

Abstract

Background: Periodontitis is a periodontal disease that affects more than 743 million peopleworldwide and causes damage to the periodontal ligament and alveolar bone. One of the bacteriathat can cause periodontitis is Porphyromonas gingivalis (P.gingivalis). P. gingivalis has virulence factors that can damage the periodontal tissue. Treatment of periodontitis is in the form of non- surgical therapy such as scaling and root planning and some cases, doxycycline can be given as adjunctive therapy after scaling and root planing. Epigallocatechin gallate (EGCG) is one of the catechins found in green tea and has anti-bacterial properties. Purpose: The study aimed to describe the potency of the mucoadhesive gingival patch with EGCG green tea against the number of macrophage cells and lymphocyte cells during periodontitis through narrative review. Review: Mucoadhesive gingiva patch loaded with EGCG has the advantages such as maintaining drug bioavailability, non-invasive, and optimizing drug distribution. Using a mucoadhesive gingiva patch with EGCG can reduce macrophage and lymphocyte cells by inhibiting lipopolysaccharide, a virulence factor of P. gingivalis. Inhibited lipopolysaccharide will inhibit pro-inflammatory cytokines such as TNF-α and IL-6. Macrophage and lymphocyte cells will reduce due to the inhibition of pro inflammatory cytokines. Conclusion: Mucoadhesive gingiva patch with EGCG green tea potentially to decreased macrophage and lymphocyte cells in periodontitis.
The Effect of PDLSCs on Orthodontic Tooth Movement – A Review Yuliati Yuliati; Indah Listiana Kriswandini; Olivia Halim
Indonesian Journal of Dental Medicine Vol. 6 No. 2 (2023): July - December
Publisher : Faculty of Dental Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijdm.v6i2.2023.79-82

Abstract

Background: Stem cells have been widely used in various fields of the health sector, one of which is dental health. Teeth with malocclusion require orthodontic treatment to achieve good function and aesthetics. Orthodontic tooth movement (OTM) occurs due to a bone remodeling process, namely deposition in areas of tension and resorption in areas of pressure. Differentiated stem cells are thought to influence OTM through several different mechanisms. Purpose: This narrative review seeks to explain how stem cells affect the mobility of orthodontic teeth. Review(s): OTM is aided by inflammatory mediators that are produced as a result of the induction of stem cells in the periodontal ligament. These mediators control osteoclast and osteoblast differentiation and proliferation, as well as bone remodeling. Periodontal ligament stem cells (PDLSCs) are important local immune response modulators in the inflammatory milieu and have an impact on a range of immune cells. Conclusion: PDLSCs, which are included in mesenchymal stem cells (MSCs), play a role in OTM through various mechanisms that can cause acceleration in OTM.
Co-Authors Dania Maharani Dian W Damaiyanti Indah Listiana Kriswandini Indeswati Diyatri Ira Arundina Jenny Sunariani Jihan Hijriya Nabilla Latief Mooduto Noven Suprayogi, Noven Olivia Halim Pratiwi Soesilawati Reinaya Tifa Pratiwi Rini Devijanti Ridwan Sidarningsih Sidarningsih, Sidarningsih