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All Journal Folia Medica Indonesiana Journal of Agromedicine and Medical Sciences Global Medical and Health Communication Jurnal Media Gizi Indonesia (MGI) The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Health Notions Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Oto Rhino Laryngologica Indonesiana JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Jurnal Pengabdian Kesehatan Masyarakat
Mahrus A. Rahman
Departement Of Child Health, Dr. Soetomo General Hospital, Faculty Of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo No. 6-8, Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Indian Journal of Forensic Medicine

 1 
Pulmonary Artery Hypertension in Acyanotic Congenital Heart Disease Underwent Transcatheter Closure at Dr. Soetomo Hospital I Ketut Alit Utamayasa1 , Mahrus A Rahman1 , Taufiq Hidayat1 , Teddy Ontoseno1
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13572

Abstract

Background: Pulmonary artery hypertension (PAH) is common complication of congenital heart disease.Echocardiography before and after transcatheter closure procedure is needed for further evaluation.Objective: To evaluate the PAH before and after transcatheter closure procedure by echocardiography atDr. Soetomo Hospital.Methods: Medical record patients with acyanotic congenital heart disease with PAH and already donetranscatheter closure procedure in 2010 – 2014 were reviewed. Data taken were demographic, clinical,and echocardiography. Tricuspid regurgitation pressure gradient (TRPG) was evaluated. Statistical analysisusing t test comparative study; P<0.05 was considered significant.Results: There were 46 patients underwent transcatheter closure, ASD closure 22/46, VSD closure 16/46,PDA closure 8/46 patients. Ten patients with PAH (10/46), 4/10 ASD, 4/10 PDA and 2/10 VSD. Boys were6/10, median age was 60 (range 4-144 months). Median TRPG before procedure was 32.4 (range 25-43mmHg). Median TRPG after procedure was 21.5 (range 15-26.9 mmHg). There was significant decreased inPAH after transcatheter closure procedure (P=0.01).Conclusion: Transcatheter closure procedure in acyanotic congenital heart disease was important fordecreasing the pressure gradient of PAH.
Caracteristics, Diagnosis, Management and Output of Persistent Pulmonary Hypertension of the Newborn at Dr. Soetomo Hospital Mardiyan Aprianto1 , Mahrus A Rahman1 , Martono Tri Utomo1
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13587

Abstract

Background Persistent pulmonary hypertension of the new-born (PPHN) is a failure of lung circulation innew-born. However the data related the characteristics of clinical profile, diagnostic, management and theoutcome was still limited.Objective To investigated the characteristics, diagnostics, management and outcome from PPHN.MethodsRetrospective observational study. Neonates with PPHN from January 2015 to December 2019 wereidentified from medical record. After the data was excluded, the characteristics, diagnostic, management andthe outcome was collected. The statistical analysis to known the frequency and the chi-square test used toanalyse the association between the treatment and the outcomes (P < 0.05).Results 37 medical records enrolled the study, with the characteristics; 62.2% babies was boy, 70.3% withterm infant, 70.3% with normal birth weight, 24.3% with maternal history of eclampsia. 62.2% babiesborn by C-section, 21.9% with history of asphyxia and MAS. 78.4% with differences between pre- andpost-ductal saturation. From echocardiography result, 13.5% diagnosed as mild PPHN, 54.1% as moderatePPHN and 32.4% severe PPHN. From the management consisted of 5.4% with O2 nasal, 32.4% O2 CPAPand 62.2% O2 ventilator, 24.3% with sildenafil, 5.4% with combination sildenafil and illoprost, 5.4% withcombination sildenafil, illoprost, and surfactant, 2.7% with combination sildenafil, illoprost, surfactant,and inotropic, 24.3% with combination sildenafil, illoprost, and inotropic, and 37.8% with combinationsildenafil and inotropic. The outcomes was obtained 35.1% babies was died and 64.9% babies was cured,with oxygenation supplementation had significantly affecting the outcomes (P=0.02)Conclusion The characteristics of PPHN was dominated by baby boy, term infant and good birth weight,history of asphyxia and MAS, maternal history of eclampsia, C-section delivery and the differences betweenpre- and post-ductal saturation. The diagnosis commonly with moderate PPHN. The management with O2ventilator and combination sildenafil-inotropic. The outcome mostly the babies was cured.
Echocardiographic Study in Preterm Infant with Hemodynamic Significant Patent Ductus Arteriosus Sunny Mariana Samosir; Martono Tri Utomo; Mahrus A. Rahman; Risa Etika; Dina Angelika; Kartika Darma Handayani; Agus Harianto
Indian Journal of Forensic Medicine & Toxicology Vol. 16 No. 1 (2022): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v16i1.17650

Abstract

Background: Potential complications of hemodynamic significant patent ductus arteriosus (hsPDA) after birth include heart failure, need for respiratory support, renal disfunction, intraventricular hemorrhage, as well as long term altered growth and development. Nevertheless, clinical signs of patent ductus arteriosus (PDA) are not sensitive and specific enough. Therefore, echocardiography still remains the preferred method to evaluate the ductal patency in preterm infant. The present study aimed to evaluate the echocardiography characteristic in preterm infant with hsPDA.Methods: A cross-sectional study was conducted on preterm infants aged 3-7 days with 24-336/7 weeks of gestation. Data taken were demographic, clinical and echocardiography. Diagnosis of hsPDA was carried out by echocardiography; defined as >1.5mm diameter of ductus and >1.4 left pulmonal artery and aorta (La/Ao) ratio. The statistical analysis was undertaken using SPSS 21.0.Results: There were 11 out of 52 preterm infants diagnosed hsPDA. Mean birth weight was 1213±293 gram; Mean gestational age was 30.72±2.01 weeks. In hsPDA group, mean ductus diameter was 2.84±0.93 mm, mean La/Ao ratio was 1.56±0.26, and mean ejection fraction (EF) was 71.55±5.72%.Conclusion: Echocardiographic evaluation is important for addressing hsPDA in preterm infants.
Clinical Profile of Pediatric Patients with Acyanotic Congenital Heart Disease in Dr. Soetomo General Hospital Surabaya Kartika Hardiyani; Taufiq Hidayat; Alit Utamayasa; Mahrus Abdur Rahman; Teddy Ontoseno
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14306

Abstract

Congenital Heart Diseases (CHD) are classified as Acyanotic or Cyanotic CHD. Prevalence of CHDaccording to various studies is 8-10 per 1000 live births worldwide, 10% of cases became infant mortalityin developing countries. This research aims to study the characteristics and clinical presentations in childrenwith acyanotic CHD in Dr. Soetomo General Hospital. A retrospective observational study from children withacyanotic type of CHD from medical record outpatient clinic in the Division of Neonatology and PediatricWard at Dr. Soetomo General Hospital from June to December 2016. Age, sex, heart defect, comorbid andnutritional status were taken from the medical record. The most dominant clinical profile was female witha mean age of 4 years. Atrial Septal Defect was the most common type of left-to-right shunt, followed byVentricular Septal Defect, and Patent Ductus Arteriosus. Pulmonary Stenosis was the most common typeof obstructive lesion, followed by Aortic Stenosis. Complications of acyanotic CHD were dominated byrecurrent respiratory tract infections followed by growth and developmental disorder, and heart failure. Themost common nutritional status was moderate malnutrition.
Co-Authors Achmad Lefi Agus Harianto Alit Utamayasa Budiono budiono Chaq El Chaq Zamzam Multazam Cintya Dipta Dina Angelika Evisina Hanafiati Frans Fatchul Wahab Henry Wicaksono Heroe Soebroto I Dewa Gede Ugrasena Juliana Juliana Kartika Darma Handayani Kartika Hardiyani Martono Tri Utomo Mia Puspitasari Nabila Izzati Ni Wayan Thirthaningsih Nyilo Purnami Ovin Nada Saputri R Fatchul Wahabe Rina Elizabeth Rio Herdyanto Risa Etika, Risa Roedi Irawan Saraswati Dewi Sarmanu Sarmanu Saskia Ratna Desita Sunny Mariana Samosir Taufiq Hidayat Teddy Ontoseno Teddy Ontoseno Teddy Ontoseno Teddy Ontoseno Teddy Ontoseno Vinny Yoanna Viskasari P. Kalanjati Wiwin Retnowati Yan Efrata Sembiring Yudi Her Oktaviono, Yudi Her