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All Journal Jurnal Ilmu Dasar UNEJ e-Proceeding PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal farmasi UIN Alauddin Makassar E-JRM
Nuri Nuri
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Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Public Health

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INHIBITORY EFFECT OF NON-POLAR AND SEMI-POLAR FRACTIONS OF ETHANOLIC EXTRACT OF Guazuma ulmifolia Lamk. LEAVES ON RAT PREADIPOCYTES PROLIFERATION AND DIFFERENTIATION Nuri Nuri; Sukardiman Sukardiman; Bambang Prayogo
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Jati Belanda Leaves (G. ulmifolia Lamk.) has beenused traditionally to reduce obesity 1). G. ulmifoliaLamk. leaves extract contained alkaloids, tannins,saponins, flavonoids, terpenoids, glycosides, andsteroids 2). Phytochemical screening resultsconducted by Iswantini et al. showed that theflavonoids and tannins were detected high levels inthis extract 3). Flavonoids contained in the leaves ofG. ulmifolia Lamk. were catechin, kaempferolglycosides, procyanidin B-2, procyanidin B-5,procyanidin C-14).Obesity can occur when the body of excess adiposetissue (fat), particularly white adipose. Excess whiteadipose tissue (WAT) is considered as the maincause of obesity 5). The growth of adipose tissueoccurs due to the formation of new adipocytes andincrease in size of adipocytes, called adipogenesis.Adipogenesis involves the multiplication of cells(proliferation) and cell maturation (differentiation).The treatment which can affect the size and numberof adipocytes and signals expression are involved inthe inhibition or stimulation of specific adipokineshave been used to prove the bioactivity associatedwith antiobesity 6).Natural products that have a specific target in thispathway have the potential to prevent and treatobesity. Some polyphenols, including flavonoidshave anti-obesity effects and also specific effects onadipocytes 7). The presence of the flavonoids i.e.catechin, kaempferol, tilirosida, and prosianidin in G.ulmifolia Lamk leaves. may affect adipogenesis.This research will be conducted extraction andfractionation leaves of G. ulmifolia Lamk. Extracts,non-polar fractions and semi-polar fractions testedtheir effect on the proliferation and differentiationof Wistar rat preadiposit.
Chromatogram and Spectram Profiles Antimalarial Isolate from Dichloromethane Extract of Artocarpus champeden Spreng. Stem Bark Nuri Nuri
Jurnal ILMU DASAR Vol 8 No 2 (2007)
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Jember

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Abstract

The isolate which possessed antimalarial activity had been isolated from dichloromethane extract of Artocarpus champeden Spreng. Stem bark. The isolate inhibited Plasmodium falciparum growth in vitro by IC 0.024±0.011 μg/ml. Chromatogram and spectram of isolate analysis showed that it contained flavonol as a  major compound.
OPTIMASI ASAM TARTRAT DAN NATRIUM BIKARBONAT GRANUL EFFERVESCENT KOMBINASI EKSTRAK DAUN Guazuma ulmifolia Lam. DAN KELOPAK Hibiscus sabdariffa L. Dwi Nurahmanto; Dita Isnaini Prabawati; Bawon Triatmoko; Nuri Nuri
Jurnal Farmasi UIN Alauddin Makassar Vol 7 No 2 (2019): Jurnal Farmasi Volume 7 Nomor 2
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/jurfar.v7i2.11573

Abstract

Guazuma ulmifolia Lam. dan Hibiscus sabdariffa L. secara empiris digunakan sebagai jamu untuk menurunkan kadar kolesterol dalam darah. Jamu yang mengandung ekstrak tersebut memiliki rasa yang pahit dan aroma yang tidak menyenangkan. Penelitian ini dibuat sediaan granul effervescent dari kombinasi ekstrak daun Guazuma ulmifolia Lam. dan ekstak Kelopak Bunga Hibiscus sabdariffa L. Formulasi dalam bentuk granul effervescent, terdiri dari sumber asam dan basa yaitu asam tartrat dan natrium bikarbonat. Granul effervescent dapat memperbaiki rasa dan aroma. Penelitian ini bertujuan untuk mengetahui formula optimum yang memiliki sifat fisik granul effervescent yang baik.  Penelitian ini dilakukan berdasarkan metode desain faktorial dengan dua faktor dan dua level yang menghasilkan empat formula yaitu formula (1), a, b, dan ab. Sifat fisik granul effervescent yang diuji adalah kelembaban dan waktu larut. Hasil menunjukkan bahwa peningkatan konsentrasi natrium bikarbonat dapat menurunkan kelembaban dan waktu larut. Sedangkan, peningkatan konsentrasi asam tartrat justru sebaliknya. Formula optimum yang diperoleh dalam penelitian ini mengandung asam tartrat 600 mg dan natrium bikarbonat 1209 mg. Formula tersebut memiliki komposisi yang sama seperti formula b.
Optimasi Formula Granul Effervescent Kombinasi Ekstrak Kelopak Bunga Hibiscus Sabdariffa L. dan Ekstrak Daun Guazuma Ulmifolia Lam. Dwi Nurahmanto; Marsalita Irine Prabandari; Bawon Triatmoko; Nuri Nuri
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 14 No. 02 Desember 2017
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (839.031 KB) | DOI: 10.30595/pharmacy.v14i2.2031

Abstract

Guazuma ulmifolia Lam. dan Hibiscus sabdariffa L. dapat digunakan untuk menurunkan kadar kolesterol dalam darah. Penelitian ini membuat sediaan granul effervescent dari kombinasi ekstrak daun Guazuma ulmifolia Lam. dan ekstak Kelopak Bunga Hibiscus sabdariffa L. Jamu yang mengandung ekstrak tersebut biasanya memiliki rasa yang pahit. Formulasi dalam bentuk effervescent, dengan asam sitrat dan natrium bikarbonat sebagai sumber asam dan basa, dapat memperbaiki sifat yang kurang menyenangkan tersebut. Penelitian ini bertujuan untuk mengetahui formula optimum yang memiliki sifat fisik granul effervescent yang baik. Penelitian ini dilakukan berdasarkan metode desain faktorial dengan dua faktor dan dua level yang menghasilkan empat formula yaitu formula (1), a, b, dan ab. Sifat fisik granul effervescent yang diuji adalah kelembaban dan waktu larut. Hasil menunjukkan bahwa peningkatan konsentrasi natrium bikarbonat dapat menurunkan kelembaban dan waktu larut. Sedangkan, peningkatan konsentrasi asam sitrat justru sebaliknya. Formula optimum yang diperoleh dalam penelitian ini mengandung asam sitrat 600 mg dan natrium bikarbonat 1440 mg. Formula tersebut memiliki komposisi yang sama seperti formula b.
PENGARUH MOTIVASI KERJA, LINGKUNGAN KERJA DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN (Studi Kasus Pada karyawan PT. Selecta Kota Wisata Batu) Nuri Nuri; Abdul Kodir Djaelani; Afi Rahmat Slamet
E-JRM : Elektronik Jurnal Riset Manajemen eJrm Vol. 8 No. 01 April 2019
Publisher : UNIVERSITAS ISLAM MALANG

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Abstract

ABSTRACT This study aims to determine how the influence of work motivation, work environment and work discipline variables on the performance of employees of PT. Selecta Batu Tourism City. Research is used by using explanatory methods with quantitative methods on employees of PT. Selecta Batu Tourism City. The sample used in this study amounted to 57 employees. The analytical method used in this study is using the SPSS program which consists of several instrument tests, normality tests, classic assumption tests, multiple linear regression analysis and hypothesis testing. The results of this study indicate that work motivation variables partially influence employee performance, work environment variables do not affect employee performance and work discipline variables do not affect employee performance. Keywords: Employee Performance, Work Motivation, Work Environment and Work Discipline
Co-Authors Abdul Kodir Djaelani Afi Rahmat Slamet Bambang Prayogo Bawon Triatmoko Dita Isnaini Prabawati Dwi Nurahmanto Dwi Nurahmanto Marsalita Irine Prabandari Sukardiman